BibTex RIS Cite

Evaluation of Skin Test Results for Childhood Who have Asthma by Itself or with Allergic Rhinitis

Year 2017, Volume: 11 Issue: 3, 153 - 158, 01.08.2017

Abstract

Objective: Asthma is a chronic inflammatory disease caused by genetic and environmental factors. Skin tests show type 1 hypersensitivity reactions against various allergens. Allergic triggers and degree of sensitivity against a specific agent can be determined by skin tests. In this study; the skin test results in asthmatic children, the presence of allergic rhinitis based on family history, and evaluations depending on several factors have been considered.Material and Methods: Patients who had been diagnosed and monitored with asthma together with allergic rhinitis and had no any other disease were enrolled in to the study. A standard data form was completed for each patient. Pulmonary function tests were performed. Skin prick tests were also performed for each patient. Results were assessed depending on atopy in the family history and diagnostic groups of Asthma / Asthma and Allergic Rhinitis.results: In this study, 236 asthmatic patients in total who were 6-18 years old were included: 155 (65.7%) were male and the mean age was 7.9 (7.4-12.2) (IQR) years. The number of asthmatic patients was 163 while the number of patients who had both asthma and allergic rhinitis was 73. The frequency of sensitivity to at least one allergen was 42.6 % according to the result of the skin test. The maximum sensitivity was for pollens with a rate of 23.6%. Atopy frequency

References

  • Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31:143- 78.
  • Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H; ISAAC Phase Three Study Group. World wide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC PhasesOne and three repeat multi country cross-sectional surveys. Lancet 2006; 368:733-43.
  • Turktas I, Selcuk ZT, Kalyoncu AF. Prevalence of asthma-associated symptoms in Turkish children. Turk J Pediatr 2001;43:1-11.
  • Ones U, Akçay A, Tamay Z, Güler N, Zincir M. Rising trend of asthma prevalence among Turkish school children (ISAAC phases I and III). Allergy 2006;61:1448-53.
  • Çelik GE. Astım epidemiyolojisi ve risk faktörleri. Demirel YS (ed). Astım Tanım ve Tedavi 1. baskı Ankara: Bilimsel Tıp Yayınevi, 2004:9-37.
  • Eriksson J, Bjerg A, Lotvall J, Wennergren G, Ronmark E, Toren K, et al. Rhinitis phenotypes correlate with different symptom presentation and risk factor patterns of asthma. Respir Med 2011;105:1611-21.
  • Bergeron C, Hamid Q. Relationship between Asthma and rhinitis: Epidemiologic, pathophysiologc, and therapeutic aspects. Allergy Asthma Clin Immunol 2005;1:81-7.
  • Boulet LP, Boulay MÈ. Asthma-related comorbidities. Expert Rev Respir Med 2011;5:377-93.
  • Kalyoncu AF, Selçuk ZT, Enünlü T, Demir AU, Çöplü L, Şahin AA, et al. Prevalence of asthma and allergic diseases in primary school children in Ankara, Turkey: Two cross-sectional studies, five years apart. Pediatr Allergy Immunol 1999;10:261-5.
  • Cengizlier MR, Mısırlıoğlu ED. Evaluation of risk factors in patients diagnosed as bronchial asthma. Allergol Immunopathol (Madr) 2006; 34:4-9.
  • Sears MR, Burrows B, Flannery EM, Herbison GP, Holdaway MD. Atopy in childhood. I. Gender and allergen related risks for development of hay fever and asthma. Clin Exp Allergy 1993; 23:941-8.

Astımlı ve Astım-Alerjik Rinit Birlikteliği Olan Çocuklarda Deri Testi Sonuçlarının Değerlendirilmesi

Year 2017, Volume: 11 Issue: 3, 153 - 158, 01.08.2017

Abstract

Amaç: Astım genetik ve çevresel faktörlerin etkisiyle ortaya çıkan kronik inflamatuvar bir hastalıktır. Deri testi, çeşitli alerjenlere karşı olan Tip 1 aşırı duyarlılık reaksiyonunu göstermektedir. Deri testleri ile alerjik tetikleyiciler ve spesifik bir ajana karşı hassasiyetin derecesi saptanabilir. Çalışmada; astımlı çocuklarda yapılan deri testi sonuçları; aile öyküsü, eşlik eden alerjik rinit varlığı ve çeşitli faktörlere bağlı sonuçların değerlendirilmesi amaçlanmıştır.Gereç ve Yöntemler: Çalışmaya, 6-18 yaş grubunda kliniğimizde astım tanısı ile takip edilen eşlik eden alerjik rinit dışında kronik hastalığı olmayan hastalar alındı. Her hastaya standart veri toplama formu dolduruldu. Solunum fonksiyon testi yapıldı. Her hastaya deri testi uygulandı. Sonuçlar ailede atopi öyküsü ve tanı gruplarına (Astım/ Astım+ Alerjik Rinit) göre değerlendirildi.Bulgular: Çalışmaya toplam 236 astımlı hasta dahil edildi. Olguların 155’i (%65.7) erkek ve yaş ortalaması 7.9 (7.4-12.2) (IQR) yıldı. Astımlı hasta sayısı 163 iken; 73 hastada hem astım hem alerjik rinit mevcuttu. Deri testi sonuçlarına göre en az bir alerjene karşı duyarlılık sıklığı %42.6 bulundu. En fazla duyarlılık %23.6 ile genel polen duyarlılığıydı. Tanı gruplarına göre astımlı hastalarda atopi sıklığı %39 iken eşlik eden alerjik rinit varlığında bu oran %52.1 bulundu (p=0.061). Ailede atopi öyküsü olan grupta alerjen duyarlılığı %39.8 iken öykü vermeyen grupta %44.3 (p=0.496) bulundu.Sonuç: Çocukluk çağı astımında alerjen duyarlılığı önemli rol oynamaktadır. Astım tanısı konulan her hastada alerjen duyarlılığı araştırılmalıdır. Deri testi yapılan her hastanın sosyodemografik özellikleri, aile öyküsü, eşlik eden diğer alerjik hastalıklar açısından dikkatle sorgulanması gerekmektedir. Çalışmamızda en çok genel polen duyarlılığı bulunması bölgemizde daha önce yapılan çalışmalarla benzerlik göstermektedir. Astım ve alerjik rinit birlikteliği olan grupta alerjen duyarlılığı sıklığı beklenildiği gibi daha fazla bulunmuştur. Aile öyküsü olan grupta daha fazla alerjen duyarlılığı olması beklenirken bizim çalışmamızda alerjen duyarlılığının daha düşük olduğu tespit edilmiştir

References

  • Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31:143- 78.
  • Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H; ISAAC Phase Three Study Group. World wide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC PhasesOne and three repeat multi country cross-sectional surveys. Lancet 2006; 368:733-43.
  • Turktas I, Selcuk ZT, Kalyoncu AF. Prevalence of asthma-associated symptoms in Turkish children. Turk J Pediatr 2001;43:1-11.
  • Ones U, Akçay A, Tamay Z, Güler N, Zincir M. Rising trend of asthma prevalence among Turkish school children (ISAAC phases I and III). Allergy 2006;61:1448-53.
  • Çelik GE. Astım epidemiyolojisi ve risk faktörleri. Demirel YS (ed). Astım Tanım ve Tedavi 1. baskı Ankara: Bilimsel Tıp Yayınevi, 2004:9-37.
  • Eriksson J, Bjerg A, Lotvall J, Wennergren G, Ronmark E, Toren K, et al. Rhinitis phenotypes correlate with different symptom presentation and risk factor patterns of asthma. Respir Med 2011;105:1611-21.
  • Bergeron C, Hamid Q. Relationship between Asthma and rhinitis: Epidemiologic, pathophysiologc, and therapeutic aspects. Allergy Asthma Clin Immunol 2005;1:81-7.
  • Boulet LP, Boulay MÈ. Asthma-related comorbidities. Expert Rev Respir Med 2011;5:377-93.
  • Kalyoncu AF, Selçuk ZT, Enünlü T, Demir AU, Çöplü L, Şahin AA, et al. Prevalence of asthma and allergic diseases in primary school children in Ankara, Turkey: Two cross-sectional studies, five years apart. Pediatr Allergy Immunol 1999;10:261-5.
  • Cengizlier MR, Mısırlıoğlu ED. Evaluation of risk factors in patients diagnosed as bronchial asthma. Allergol Immunopathol (Madr) 2006; 34:4-9.
  • Sears MR, Burrows B, Flannery EM, Herbison GP, Holdaway MD. Atopy in childhood. I. Gender and allergen related risks for development of hay fever and asthma. Clin Exp Allergy 1993; 23:941-8.
There are 11 citations in total.

Details

Other ID JA72RK28FN
Journal Section Research Article
Authors

Sultan Ay This is me

Ersoy Civelek This is me

Elif Kınık Kaya This is me

Hakan Güvenir This is me

Emine Dibek Misirlioglu This is me

Müge Toyran This is me

Betül Büyüktiryaki This is me

Tayfur Giniş This is me

Can Naci Kocabaş This is me

Publication Date August 1, 2017
Submission Date August 1, 2017
Published in Issue Year 2017 Volume: 11 Issue: 3

Cite

Vancouver Ay S, Civelek E, Kaya EK, Güvenir H, Misirlioglu ED, Toyran M, Büyüktiryaki B, Giniş T, Kocabaş CN. Evaluation of Skin Test Results for Childhood Who have Asthma by Itself or with Allergic Rhinitis. Türkiye Çocuk Hast Derg. 2017;11(3):153-8.


The publication language of Turkish Journal of Pediatric Disease is English.


Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.


The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.