Hyperleukocytosis is seen in 5-20% of childhood leukemia cases and it is a poor prognostic factor. Leukapheresis is an effective emergency treatment method by reducing the number of blasts and control of neurological symptoms. Here we report a pediatric patient whose physical status was ASA IVE. He was diagnosed as acute leukemia and had neurologic deterioration together with late recovery from anesthesia after central venous catheterization. Morbidity and mortality of central venous catheterization, which is necessary for leukapheresis treatment, is high. Therefore, all the risks of the disorder and the central catheterization procedure should be described in detail to the family by clinician and the anesthesiologist during preoperative evaluation. We suggest using local anesthesia during this procedure in suitable cases and avoiding sedation or general anesthesia. When there is disorientation, we must remember that this can be a sign of a cerebrovascular event
Hiperlölositoz, çocukluk çağı lösemilerinin %5-20’sinde görülen, prognozu kötü etkileyen bir risk faktörüdür. Lökoferez bu hasta grubunda, blast sayısını etkin bir şekilde azaltarak nörolojik semptomların kontrolünü sağlayan, etkili, acil bir tedavi yöntemidir. Biz bu olgu sunumunda, hiperlökositoz nedeniyle lökoferez planlanan, ASA IVE, çocuk hastada santral venöz kateterizasyon sırasında gelişen nörolojik dezoryantasyon ve geç derlenmeyi tartışmayı planladık. Lökoferez için uygulanacak santral venöz kateterizasyon morbidite ve mortalitesi yüksek bir girişimdir. İşlemden önce, hastayı takip eden klinisyen ve anestezistin, hastalığın ve santral girişimin tüm risklerini aileye ayrıntılı anlatması gerektiği, işlem sırasında mümkün olan olgularda sadece lokal anestezi uygulanması, sedasyon ve genel anesteziden kaçınılması, hastanın bilinç durumunda bozulma olduğunda serebrovasküler olayların akla getirilerek hızla tanı ve tedavi için değerlendirilmesi gerektiği kanaatindeyiz.
Other ID | JA69AM42RS |
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Journal Section | Case Report |
Authors | |
Publication Date | April 1, 2017 |
Submission Date | April 1, 2017 |
Published in Issue | Year 2017 Volume: 11 Issue: 1 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.