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Celiac Disease? Should We Screen Children with Functional Constipation for

Year 2016, Volume: 10 Issue: 4, 249 - 252, 01.12.2016

Abstract

Objective: Diagnostic tests may be needed to exclude organic disease in children with constipation. Constipation may be the presenting symptom of celiac disease. We aimed to determine the characteristics of defecation and the prevalence of celiac disease in children with functional constipation. Material and Methods: The medical records of 150 children diagnosed with functional constipation according to Rome III criteria were evaluated retrospectively. Results: One-hundred and fifty children [74 girls (49.3%)], with a mean age of 6.5 ± 4.2 years, had a history of constipation for a median duration of 24 months. The mean presentation age of constipation was 3.6 ± 3.7 years. Children with painful defecation were younger than the others (3.1 ± 3.4 years, vs. 5 ± 4.3 years, respectively, p= 0.018). Children with large and firm stools (7.7 ± 4.3 years) were older than children with pebble stone like stools (5.2 ± 4.2 years) and children with both large and pebble stone like stools (5 ± 3.5 years) (p = 0.002, p = 0,003, respectively). Painful defecation, rectal bleeding and encopresis were more frequent in children with stool holding behaviour (p = 0.034, p = 0.001, p = 0.001, respectively). History of urinary tract infection was more frequent in older children and girls (36 girls, 67.9%) (p = 0.008, p = 0.001, respectively). One (0.65%) patient who had tissue transglutaminase IgA positivity was diagnosed as celiac disease with small bowel biopsy.Conclusion: Celiac disease was not found more frequent in children with functional constipation

References

  • Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, et al. Childhood functional gastrointestinal disorders: Child/adolescent. Gastroenterology 2006;130:1527-37.
  • Morais MB, Maffei HV. Constipation. J Pediatr (Rio J) 2000;76 Suppl 1:S147-S56.

Fonksiyonel Kabızlığı Olan Çocuklarda Çölyak Hastalığı Taramalı mıyız?

Year 2016, Volume: 10 Issue: 4, 249 - 252, 01.12.2016

Abstract

Amaç: Kabızlık yakınması ile getirilen çocuklarda organik nedenlerin dışlanması için tanısal testlere ihtiyaç duyulabilir. Kabızlık çölyak hastalığının ilk bulgusu olabilir. Çalışmada fonksiyonel kabızlık tanısı alan çocuklarda dışkılama özelliklerinin ve çölyak hastalığı sıklığının belirlenmesi amaçlandı.Gereç ve Yöntemler: Roma III ölçütlerine göre fonksiyonel kabızlığı olan 150 çocuk dosya taraması ile geriye dönük olarak değerlendirildi.Bulgular: Ortalama 6,5 ± 4,2 (1-17) yaşında olan, 150 çocuğun [74 kız (% 49.3)], ortanca 24 (1-198) aydır kabızlığı vardı. Ortalama kabızlık başlangıç yaşı 3,6 ± 3,7 yıldı. Ağrılı dışkılaması olanlar (ortalama 3.1 ± 3.4 yıl), diğerlerinden (ortalama 5 ± 4.3 yıl) daha küçüktü (p= 0.018). Büyük ve sert dışkılaması olanlar (ortalama 7.7 ± 4.3 yıl), çakıl taşı benzeri küçük ve sert yapanlara (ortalama 5.2 ± 4.2 yıl) ve her iki tipte de dışkılaması olanlara (ortalama 5 ± 3.5 yıl) göre daha büyüktü (sırasıyla p = 0.002, p = 0.003). Dışkı tutma davranışı olanlarda, ağrılı dışkılama, kanama ve dışkı kaçırma sıklığı daha yüksekti (sırasıyla p = 0.034, p = 0.001, p = 0.001). İdrar yolu enfeksiyonu öyküsü büyük çocuklarda ve kızlarda (36 kız, %67.9) daha sıktı (sırasıyla p = 0.008, p = 0.001). Olguların 1’inde (% 0.65) doku transglutaminaz IgA (+) olup ince bağırsak biyopsisi ile çölyak hastalığı tanısı aldı.Sonuç: Fonksiyonel kabızlığı olan çocuklarda çölyak hastalığı sıklığı yüksek bulunmamıştır.

References

  • Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, et al. Childhood functional gastrointestinal disorders: Child/adolescent. Gastroenterology 2006;130:1527-37.
  • Morais MB, Maffei HV. Constipation. J Pediatr (Rio J) 2000;76 Suppl 1:S147-S56.
There are 2 citations in total.

Details

Other ID JA78DK79SV
Journal Section Research Article
Authors

Ceyda Tuna Kırsaçlıoğlu This is me

Zarife Kuloğlu This is me

Gonca Üstündağ This is me

Arzu Ensari This is me

Aydan Kansu This is me

Publication Date December 1, 2016
Submission Date December 1, 2016
Published in Issue Year 2016 Volume: 10 Issue: 4

Cite

Vancouver Kırsaçlıoğlu CT, Kuloğlu Z, Üstündağ G, Ensari A, Kansu A. Celiac Disease? Should We Screen Children with Functional Constipation for. Türkiye Çocuk Hast Derg. 2016;10(4):249-52.


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