Abstract
D vitamini intoksikasyonu genellikle iyatrojenik olup uygunsuz dozda D vitamini alınmasına bağlıdır. 120 nmol/L’nin üzerinde serum 25 OHD düzeyleri D vitamini intoksikasyonu olarak kabul edilir. D vitamini intoksikasyonu son yıllarda daha çok bildirilmeye başlanmıştır. D vitamini intoksikasyonu ile ilişkili semptom ve bulgular serum kalsiyum seviyesi ile yakından ilişkilidir. Hiperkalseminin kardiak, renal, gastrointestinal ve nörolojik yan etkileri ile acil tedavisi gerekmektedir. Burada daha önce sağlıklı olan, bilinçsiz olarak aşırı doz D vitamini alımı ile ağır ve dirençli hiperkalsemi gelişen ve intravenöz pamidronat infüzyonu ile komplikasyon olmaksızın normokalsemi sağlanan13 aylık olgu sunulmuştur.
Keywords
References
- Şükrü H, Abdullah B, Ali Süha Ç, Behzat Ö. Günümüzde D vitamini yetersizliği ve nütrisyonel rikets. Çocuk Sağlığı ve Hastalıkları Dergisi 2003; 46:224-41.
- Awumey EM, Mitra DA, Hollis BW, Kumar R, Bell NH. Vitamin D metabolism is altered in AsianIndians in the Southern United States: A clinical research center study. J Clin Endocrinol Metab 1998;83:169-73.
- Kibar AE, Arhan E, Özaydın E, Kılıç G, Çakır B, Çetinkaya E, Köse G. İyatrojenik D vitamini intoksikasyonuna bağlı hiperkalsemi. Yeni Tıp Dergisi 2007; 24: 120-2.
- Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J ClinNutr 1999; 69: 842-56.
- Türkiye Çocuk Hast Derg/Turkish J Pediatr Dis / 2016; 4: 277-279
Abstract
Vitamin D intoxication (VDI) is usually iatrogenic and is due to the usage of improper doses of vitamin D. Serum 25OHD levels above 120 nmol/l are considered Vitamin D intoxication. Vitamin D intoxication has been reported more frequently in recent years. The symptoms and findings associated with VDI are closely related to serum calcium concentration. Emergency intervention is necessary because of the adverse effects of hypercalcemia on cardiac, neurologic, renal, and gastrointestinal functions.We present a previously healthy, 13-month-old infant with severe and resistant hypercalcemia due to unconscious overdose with vitamin D supplement and its successful treatment with intravenous infusion of pamidronate with no complications
Keywords
References
- Şükrü H, Abdullah B, Ali Süha Ç, Behzat Ö. Günümüzde D vitamini yetersizliği ve nütrisyonel rikets. Çocuk Sağlığı ve Hastalıkları Dergisi 2003; 46:224-41.
- Awumey EM, Mitra DA, Hollis BW, Kumar R, Bell NH. Vitamin D metabolism is altered in AsianIndians in the Southern United States: A clinical research center study. J Clin Endocrinol Metab 1998;83:169-73.
- Kibar AE, Arhan E, Özaydın E, Kılıç G, Çakır B, Çetinkaya E, Köse G. İyatrojenik D vitamini intoksikasyonuna bağlı hiperkalsemi. Yeni Tıp Dergisi 2007; 24: 120-2.
- Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J ClinNutr 1999; 69: 842-56.
- Türkiye Çocuk Hast Derg/Turkish J Pediatr Dis / 2016; 4: 277-279
Details
| Other ID | JA86NY62SY |
|---|---|
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 1, 2016 |
| Submission Date | December 1, 2016 |
| Published in Issue | Year 2016 Volume: 10 Issue: 4 |
The publication language of Turkish Journal of Pediatric Disease is English.
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