Abstract
Çocukluk döneminde B12 vitamin eksikliği nadir görülür ve hastalar genellikle özgül olmayan hematolojik veya nörolojik bulgularla hastaneye başvururlar. B12 vitamini eksikliği sıklıkla yetersiz alım sonucu oluşmaktadır. Gelişmekte olan ülkelerde, sosyoekonomik düzeyi düşük olan annelerde B12 vitamin eksikliği yüksek oranda gelişir. Anne sütündeki B12 vitamin eksikliği ilk 2 yılda semptomlara neden olmaktadır.B12 vitamini eksikliğinin tedavisi, iyi klinik yanıt alınması ve kalıcı nörolojik hasarların önlenmesi nedeniyle önemlidir. Burada pansitopeni etiyolojisi araştırılırken B12 vitamini eksikliği tanısı alan bir olgu sunulmuştur.
References
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- Onal H, Adal E, Oner T, Onal Z, Aydın A. Gelişmekte olan ülkelerde önemli bir sorun: Annede ve yenidoğanda B12 vitamini eksikliği. Türk Ped Arş 2010;45:242-5.
- Lerner NB. 448.2 Vitamin B12 (Cobalamin) Defi ciency. In Kliegman R, Stanton B, et al. (eds). Nelson Textbook of Pediatrics. 19th ed. Philadelphia:Elsevier, 2011: 1655.
- Bay A, Oner AF, Nalbantoglu O, Demirtas M, Acıkgöz M. Megaloblastik anemili 45 olgunun klinik ve hematolojik yönden değerlendirilmesi. Van Tıp Dergisi 2006;13:46-8.
- Incecik F, Herguner MO, Altunbasak S, Leblebisatan G. Neurologic fi ndings of nutritional vitamin B12 defi ciency in children. Turk J Pediatr 2010; 52:17-21.
- Honzik T, Adamovicova M, Smolka V, Magner M, Hruba E, Zeman J. Clinical presentation and metabolic consequences in 40 breastfed infant with nutritional vitamin B12 defi ciency- What have we learned? Eur J Paediatr Neurol 2010;14:488-95.
- Oner T. Sağlıklı yenidoğanlarda ve annelerinde vitamin B12 eksikliğinin sıklığı. (Uzmanlık Tezi). İstanbul: T.C. Sağlık Bakanlığı Bakırköy Kadın Doğum ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2008.
- Koc A, Kocyigit A, Soran M, Demir N, Sevinc E, Erel O, et al. High frequency of maternal vitamin B12 defi ciency as an important cause of infantile vitamin B12 defi ciency in Sanliurfa province of Turkey. Eur J Nut 2006;45: 291-7.
- Halicioglu O, Sutcuoglu S, Koc F, Ozturk C, Albudak E, Colak A, et al. Vitamin B12 an folate statuses are associated with diet in pregnant women, but not with anthropometric measurement in term newborns. J Matern Fetal Neonatal Med 2012; 25:1618-21.
- Baytan B, Ozdemir O, Erdemir G, Gunes AM. Çocukluk çağında vitamin B12 eksikliği klinik bulgular ve tedavi. Uludağ Üniversitesi Tıp Fakültesi Dergisi 2007;33: 61-4.
Abstract
Vitamin B12 defi ciency with non-specifi c signs is uncommon in childhood. It often develops as a result of inadequate intake. Mothers with low socioeconomic status may develop vitamin B12 defi ciency. It should be kept in mind that this defi ciency has higher incidence rates in infants at birth and during feeding with only breast milk. Lack of vitamin B12 in breast milk may cause symptoms in the fi rst 2 years of age. Treatment of vitamin B12 defi ciency is important as it ensures a good clinical response and prevention of permanent neurological damage. We present a case diagnosed with vitamin B12 defi ciency
Keywords
References
- Taskesen M, Yaramıs A, Katar S, Pirinccioglu AG, Soker M. Neurological presentations of nutritional vitamin B12 defi ciency in 42 breastfed infants in Southeast Turkey. Turk J Med Sci 2011;41:1091-6.
- Onal H, Adal E, Oner T, Onal Z, Aydın A. Gelişmekte olan ülkelerde önemli bir sorun: Annede ve yenidoğanda B12 vitamini eksikliği. Türk Ped Arş 2010;45:242-5.
- Lerner NB. 448.2 Vitamin B12 (Cobalamin) Defi ciency. In Kliegman R, Stanton B, et al. (eds). Nelson Textbook of Pediatrics. 19th ed. Philadelphia:Elsevier, 2011: 1655.
- Bay A, Oner AF, Nalbantoglu O, Demirtas M, Acıkgöz M. Megaloblastik anemili 45 olgunun klinik ve hematolojik yönden değerlendirilmesi. Van Tıp Dergisi 2006;13:46-8.
- Incecik F, Herguner MO, Altunbasak S, Leblebisatan G. Neurologic fi ndings of nutritional vitamin B12 defi ciency in children. Turk J Pediatr 2010; 52:17-21.
- Honzik T, Adamovicova M, Smolka V, Magner M, Hruba E, Zeman J. Clinical presentation and metabolic consequences in 40 breastfed infant with nutritional vitamin B12 defi ciency- What have we learned? Eur J Paediatr Neurol 2010;14:488-95.
- Oner T. Sağlıklı yenidoğanlarda ve annelerinde vitamin B12 eksikliğinin sıklığı. (Uzmanlık Tezi). İstanbul: T.C. Sağlık Bakanlığı Bakırköy Kadın Doğum ve Çocuk Hastalıkları Eğitim ve Araştırma Hastanesi, 2008.
- Koc A, Kocyigit A, Soran M, Demir N, Sevinc E, Erel O, et al. High frequency of maternal vitamin B12 defi ciency as an important cause of infantile vitamin B12 defi ciency in Sanliurfa province of Turkey. Eur J Nut 2006;45: 291-7.
- Halicioglu O, Sutcuoglu S, Koc F, Ozturk C, Albudak E, Colak A, et al. Vitamin B12 an folate statuses are associated with diet in pregnant women, but not with anthropometric measurement in term newborns. J Matern Fetal Neonatal Med 2012; 25:1618-21.
- Baytan B, Ozdemir O, Erdemir G, Gunes AM. Çocukluk çağında vitamin B12 eksikliği klinik bulgular ve tedavi. Uludağ Üniversitesi Tıp Fakültesi Dergisi 2007;33: 61-4.
Details
| Other ID | JA54FP95NU |
|---|---|
| Journal Section | Research Article |
| Authors | |
| Publication Date | April 1, 2016 |
| Submission Date | April 1, 2016 |
| Published in Issue | Year 2016 Volume: 10 Issue: 1 |
The publication language of Turkish Journal of Pediatric Disease is English.
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