BibTex RIS Cite

Akut Apandisit Ön Tanısı ile Opere Edilen Çocuk Olgularda Preoperatif Ultrasonografi Bulguları ve Beyaz Küre Sayısının Histopatolojik Tanı ile Karşılaştırılması

Year 2015, Volume: 9 Issue: 4, 231 - 234, 01.12.2015

Abstract

Amaç: Akut apandisit çocukluk çağının en sık karşılaşılan ve tanısal zorluk çekilen akut batın sebeplerinden biridir. Çalışmamızda çocuk yaş grubunda akut apandisit tanısında ultrasonografi sonuçları ve beyaz küre sayısı yüksekliğinin histopatolojik tanı ile ilişkisi ve tanısal doğruluğu değerlendirilmiştir.Gereç ve Yöntemler: Ocak 2013 ve Haziran 2014 tarihleri arasında akut apandisit ön tanısı ile apendektomi yapılan 20’si erkek, 17’si kız ve yaş ortalaması 13 olan 37 olgunun operasyon öncesi ultrasonografi ve beyaz küre düzeyleri retrospektif olarak değerlendirilmiştir. Histopatolojik tanı karşılaştırmada esas alınmıştır.Bulgular: Seçilen tüm hastaların preoperatif USG ve beyaz küre sonuçları histopatolojik sonuçlar altın standart kabul edilerek karşılaştırıldı. Buna göre USG için tanısal duyarlılık %70, seçicilik %43, doğruluk %70 bulunmuştur. Beyaz küre sayısı akut apandisit düşünülen hastalarda yüksek olup duyarlılık %82, seçicilik % 30, doğruluk %70 bulunmuştur. USG’nin akut apandisit olarak raporladığı hastaların histopatolojik incelemede akut apandisit olma olasılığı %84 bulunmuştur.Sonuç: Çocukluk çağı akut apandist olgularında tanı temel olarak anamnez, fizik muayene ve laboratuvar bulgularına dayanarak konur. İlave tetkik gerektiğinde iyonizan radyasyon içermeyen, nispeten ucuz, kolay ulaşılabilir ve tekrarlanabilir bir yöntem olan ultrasonografi ilk tercih edilmesi gereken radyolojik yöntemdir. USG ve beyaz küre sayısının yüksekliği ile histopatolojik tanı arasındaki anlamlı ilişki de bu tercihi doğrulamaktadır.

References

  • Poortman P, Lohle PN, Schoemaker CM, Oostvogel HJ, Tepen HJ, Zwinterman VA, et al. Comparison of CT and sonography in the diagnosis of acute appendicitis: A blinded prospective study. AJR Am J Roentgenology 2003;181:1355-9.
  • Campell JPM, Gunn AA. Plain abdominal radiographs and acute abdominal pain. Br J Surg 1988;75: 554-86.
  • Kniskern JH, Eskin EM, Fletcher HS. Increasing accuracy in the diagnosis of acute appendicitis with modern diagnostic techniques. Am Sur 1986;52:222-5
  • Axelrod DA, Sonnad SS, Hirschl RB. An economic evaluation of sonographic examination of children with suspected appendicitis. J Pediatr Surg 200;35:1236-41.
  • Siegel MJ. Acute appendicitis in childhood: The role of ultrasonund. Radiology 1992;185:341-2.
  • Lessin MS, Chan M, Catallozzi M, Gilchrist MF, Richards C, Manera L, et al. Selective use of ultrasonography for acute appendicitis in children. Am J Surg 1999;177:193-6.
  • Rice HE, Arbesman M, Martin DJ, Brown RL, Gollin G, Gilbert JC, et al. Does early ultrasonography affect management of pediatric appendicitis? A prospective analysis. J Pediatr Surg 1999;34:754- 8.
  • Rioux M. Sonographic detection of the normal abnormal appendix. AJR An J Roentgenol 1992;185:773-8.
  • Yamaner S. Apendiks hastalıkları. Değerli Ü, Bozfakıoğlu Y (eds), Cerrahi gastroenteroloji. 5. Baskı. İstanbul: Nobel Tıp Kitapevi, 2003:543-90.
  • Robbins SL, Kumar V, Ramzi SC. Ağız boşluğu ve gastrointestinal sistem. Temel Patoloji. Çevikbaş U (çev). 7. Baskı. İstanbul: Nobel Tıp Kitapevi, 2003:543-90.
  • Liu CD, McFadden DW. Surgery: Scientific principles and practice. 2. Greenfield LJ, et al. (eds). Philadelphia: Lippincott- Raven,1997:1246-61.
  • Ohmann C, Franke C, Yang Q. Clinical benefit of a diagnostic score for appendicitis: Results of a prospective interventional study. German Study Group of Acute Abdominal Pain. Arch Surg 1999;134:993-6.
  • Robert B. Appendicitis. In: Bondy KP, Faling JL, Frenkel EP (eds). The Merkc Manual. 15th ed. Pennsylvania: Merck Co., 1987: 757- 9.
  • Silvirman FN, Khun JP. The abdomen and gastrointestinal tract in pediatric X-ray diagnosis. Silvirman FN, Khun JP (eds). 9th ed. St. Louis, Missouri: Mosby-Year Book, 1993:1109-13.
  • Sivit CJ. Diagnosis of acute appendicitis in children: Spectrum of sonographic findings. AJR 1993;161:147-52.
  • Turan A, Kaplan S, Kütükçü E, Yiğitbaş E, Hatipoğlu S, Aygün E. Comprasion of operative and nonoperative managment of aucte appendicitis. Ulusal Travma Acil Cerrahi Derg 2009;15:459-62.
  • Gaitini D, Beck-Razi N, Mor-Yosef D, Fischer D, Ben Itzhak O, Krausz MM, et al. Diagnosing acute appendicitis in adult: accuracy of color Doppler sonography and MDCT compared with surgery and clinical foolow-up. AJR Am J Reontgenol 2008;190:1300-6.
  • Scoap Collaborative, Cuschier J, Florence M, Flum DR, Jurkovich GJ, Lin P, et al. Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcome Assessment Program. Ann Surg 2008;248:557-63.
  • Binnebösel M, Otto J, Stumpf M, Manhken AH, Gassler N, Schumpelick V, et al. Acute appendicitis. Modern diagnostic- surgical ultrasound. Chirurg 2009;80:579-87.
  • Memisoglu K, Karip B, Mestan M, Onur E. The value of preoperative diagnostic test in acute appendicitis, retrospective analysis of 196 patients. World Emerg Surg 2010;5:5.
  • Rosai and Ackerman’s Surgical Pathology. Rosa J (ed). 9th ed. Vol I: 2004:757-68.

The Comparison of Histopathological Diagnosis and Preoperative Ultrasonography and WBC Results of Cases Operated on with a Prediagnosis of Childhood Acute Appendicitis

Year 2015, Volume: 9 Issue: 4, 231 - 234, 01.12.2015

Abstract

Objective: Acute appendicitis is one of the reasons of acute abdomen that is very common in the childhood period and creates difficulty in diagnosis. In this study, the diagnostic accuracy and correlation between the histopathological diagnosis and the results of ultrasonography in childhood period acute appendicitis diagnosis and the WBC elevation rate were evaluated.Material and Methods: Between January 2013 and June 2014, preoperative ultrasonography and WBC (White Blood Cell) levels of 37 cases with a pre-diagnosis of acute appendicitis consisting of 20 males and 17 females with a mean age of 13 years and undergoing appendectomy were evaluated restrospectively. The histopathological diagnosis was the basis of the correlation.results: The results of pre-operative USG and WBC of the selected patients were compared taking the histopathological result as the gold standard. In this respect, the rates for USG were as follows: diagnostic sensitivity 78%, selectivity 43%, and accuracy 70%. WBC was high in the patients with a possibility of acute appendicitis. In these patients the rates were sensitivity 83%, selectivity 30%, accuracy 70%

References

  • Poortman P, Lohle PN, Schoemaker CM, Oostvogel HJ, Tepen HJ, Zwinterman VA, et al. Comparison of CT and sonography in the diagnosis of acute appendicitis: A blinded prospective study. AJR Am J Roentgenology 2003;181:1355-9.
  • Campell JPM, Gunn AA. Plain abdominal radiographs and acute abdominal pain. Br J Surg 1988;75: 554-86.
  • Kniskern JH, Eskin EM, Fletcher HS. Increasing accuracy in the diagnosis of acute appendicitis with modern diagnostic techniques. Am Sur 1986;52:222-5
  • Axelrod DA, Sonnad SS, Hirschl RB. An economic evaluation of sonographic examination of children with suspected appendicitis. J Pediatr Surg 200;35:1236-41.
  • Siegel MJ. Acute appendicitis in childhood: The role of ultrasonund. Radiology 1992;185:341-2.
  • Lessin MS, Chan M, Catallozzi M, Gilchrist MF, Richards C, Manera L, et al. Selective use of ultrasonography for acute appendicitis in children. Am J Surg 1999;177:193-6.
  • Rice HE, Arbesman M, Martin DJ, Brown RL, Gollin G, Gilbert JC, et al. Does early ultrasonography affect management of pediatric appendicitis? A prospective analysis. J Pediatr Surg 1999;34:754- 8.
  • Rioux M. Sonographic detection of the normal abnormal appendix. AJR An J Roentgenol 1992;185:773-8.
  • Yamaner S. Apendiks hastalıkları. Değerli Ü, Bozfakıoğlu Y (eds), Cerrahi gastroenteroloji. 5. Baskı. İstanbul: Nobel Tıp Kitapevi, 2003:543-90.
  • Robbins SL, Kumar V, Ramzi SC. Ağız boşluğu ve gastrointestinal sistem. Temel Patoloji. Çevikbaş U (çev). 7. Baskı. İstanbul: Nobel Tıp Kitapevi, 2003:543-90.
  • Liu CD, McFadden DW. Surgery: Scientific principles and practice. 2. Greenfield LJ, et al. (eds). Philadelphia: Lippincott- Raven,1997:1246-61.
  • Ohmann C, Franke C, Yang Q. Clinical benefit of a diagnostic score for appendicitis: Results of a prospective interventional study. German Study Group of Acute Abdominal Pain. Arch Surg 1999;134:993-6.
  • Robert B. Appendicitis. In: Bondy KP, Faling JL, Frenkel EP (eds). The Merkc Manual. 15th ed. Pennsylvania: Merck Co., 1987: 757- 9.
  • Silvirman FN, Khun JP. The abdomen and gastrointestinal tract in pediatric X-ray diagnosis. Silvirman FN, Khun JP (eds). 9th ed. St. Louis, Missouri: Mosby-Year Book, 1993:1109-13.
  • Sivit CJ. Diagnosis of acute appendicitis in children: Spectrum of sonographic findings. AJR 1993;161:147-52.
  • Turan A, Kaplan S, Kütükçü E, Yiğitbaş E, Hatipoğlu S, Aygün E. Comprasion of operative and nonoperative managment of aucte appendicitis. Ulusal Travma Acil Cerrahi Derg 2009;15:459-62.
  • Gaitini D, Beck-Razi N, Mor-Yosef D, Fischer D, Ben Itzhak O, Krausz MM, et al. Diagnosing acute appendicitis in adult: accuracy of color Doppler sonography and MDCT compared with surgery and clinical foolow-up. AJR Am J Reontgenol 2008;190:1300-6.
  • Scoap Collaborative, Cuschier J, Florence M, Flum DR, Jurkovich GJ, Lin P, et al. Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcome Assessment Program. Ann Surg 2008;248:557-63.
  • Binnebösel M, Otto J, Stumpf M, Manhken AH, Gassler N, Schumpelick V, et al. Acute appendicitis. Modern diagnostic- surgical ultrasound. Chirurg 2009;80:579-87.
  • Memisoglu K, Karip B, Mestan M, Onur E. The value of preoperative diagnostic test in acute appendicitis, retrospective analysis of 196 patients. World Emerg Surg 2010;5:5.
  • Rosai and Ackerman’s Surgical Pathology. Rosa J (ed). 9th ed. Vol I: 2004:757-68.
There are 21 citations in total.

Details

Other ID JA46FR32RP
Journal Section Research Article
Authors

Murathan Köksal This is me

Aslı Demir Şam This is me

Ferda Köksal This is me

Halil İbrahim Altan Özdemir This is me

Bilal Çelikbaş This is me

Bayram Gökhan Özcan This is me

Publication Date December 1, 2015
Submission Date December 1, 2015
Published in Issue Year 2015 Volume: 9 Issue: 4

Cite

Vancouver Köksal M, Şam AD, Köksal F, Özdemir HİA, Çelikbaş B, Özcan BG. The Comparison of Histopathological Diagnosis and Preoperative Ultrasonography and WBC Results of Cases Operated on with a Prediagnosis of Childhood Acute Appendicitis. Türkiye Çocuk Hast Derg. 2015;9(4):231-4.


The publication language of Turkish Journal of Pediatric Disease is English.


Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.


The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.