Abstract
Protein kaybettiren enteropati (PKE) serum proteinlerinin gastrointestinal sistemden kaybı ve hipoproteinemi gelişimi ile karakterize bir tablodur. Ödem, asit, malnütrisyon plevral ve perikardiyal efüzyon ile komplike hale gelebilir. Nadir görülmekle birlikte bir çok durum PKE’ye neden olabilir. PKE nedenleri eroziv- noneroziv gastrointestinal hastalıklar, santral venöz basınç artışı ile karakterize hastalıklar ve mezenterik lenfatik obstrüksiyon gelişimi ile karakterize olanlar olarak gruplanabilir. PKE tanısı, hipoproteinemi ile başvuran bir hastada malnütrisyon, proteinüri ve bozulmuş protein sentezi ile giden hastalıklar dışlandıktan sonra konulmalıdır. Tedavi, diyet modifikasyonunu da içeren destek tedaviden oluşur. Bu yazıda, farklı nedenlerle anazarka tarzı ödem ile başvuran ve farklı etiyolojilerle protein kaybettiren enteropati tanısı alan iki sütçocuğu sunulmuştur.
Keywords
References
- Uzuner O, Ziessman HA. Protein-losing enteropathy detected by Tc-99m-MDP abdominal scintigraphy. Pediatr Radiol 2008;38: 1122-4.
- Umar SB. DiBaise JK. Protein-losing Enteropathy: Case IIlustrati- ons and Clinical Review. Am J Gastroenterol 2010;105:43-9.
- Takeda H, Ishihama K, Fukui T, Fujishima S, Orii T, Nakazawa Y, et al. Signifi cance of rapid turnover proteins in protein-losing gastroenteropathy. Hepatogastroenterol 2003;50:1963-5.
- Waldmann TA, Steinfeld JL, Dutcher TF, Davidson JD, Gordon RS Jr. The role of the gastrointestinal system in “idiopathic hypoproteinemia”. Gastroenterology 1961;41:197-207.
- Braamskamp MJ, Dolman KM, Tabbers MM. Clinical practice. Protein-losing enteropathy in children. Eur J Pediatr 2010;169: 1179-85.
Abstract
Protein-losing enteropathy (PLE) is characterized by the development of hypoproteinemia and the loss of serum proteins from the gastrointestinal system. It can be complicated with edema, acid, malnutrition, and pleural and pericardial effusion. PLE is rare but has many causes. The reasons can be grouped as erosive and non-erosive gastrointestinal diseases, diseases characterized by central venous pressure increase, and diseases characterized by the development of mesenteric lymphatic obstruction. A PLE diagnosis should be made for the patient who presents with hypoproteinemia after excluding other disorders causing malnutrition, proteinuria and impaired protein synthesis. Treatment consists of a supportive treatment that includes dietary modifi cation. This paper presents two infants who developed anasarca-type edema following different causes and were diagnosed with protein-losing enteropathy due to different etiologies
Keywords
References
- Uzuner O, Ziessman HA. Protein-losing enteropathy detected by Tc-99m-MDP abdominal scintigraphy. Pediatr Radiol 2008;38: 1122-4.
- Umar SB. DiBaise JK. Protein-losing Enteropathy: Case IIlustrati- ons and Clinical Review. Am J Gastroenterol 2010;105:43-9.
- Takeda H, Ishihama K, Fukui T, Fujishima S, Orii T, Nakazawa Y, et al. Signifi cance of rapid turnover proteins in protein-losing gastroenteropathy. Hepatogastroenterol 2003;50:1963-5.
- Waldmann TA, Steinfeld JL, Dutcher TF, Davidson JD, Gordon RS Jr. The role of the gastrointestinal system in “idiopathic hypoproteinemia”. Gastroenterology 1961;41:197-207.
- Braamskamp MJ, Dolman KM, Tabbers MM. Clinical practice. Protein-losing enteropathy in children. Eur J Pediatr 2010;169: 1179-85.
Details
| Other ID | JA99YC66BZ |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 1, 2015 |
| Submission Date | April 1, 2015 |
| Published in Issue | Year 2015 Volume: 9 Issue: 1 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
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