Abstract
Hiperparatiroidizm çocukluk çağında çok nadir görülen bir hastalıktır. Genellikle bulantı, kusma, kabızlık, irritabilite, letarji, başağrısı, poliüri ve polidipsi gibi özgül olmayan semptomlarla başvurulmakta ve bu nedenle tanı konulması gecikebilmektedir. Tanı klinik inceleme ve laboratuvar bulguları ile konulur. Görüntüleme yöntemleri ile paratiroid hiperplazisi ve adenomu ayrımı yapılmaktadır. Hipokalsiürik hiperkalsemi ile karışabileceğinden idrar kalsiyum düzeylerine bakılması ayırıcı tanıda önemlidir. Paratiroid adenomunun kesin tedavisi adenomun çıkartılmasıdır. Ayrıca, kemik tutulumu ve uç organ hasarı yönünden dikkatli olunmalıdır. Burada, acil servise bulantı ve kusma yakınması ile başvuran, hiperparatiroidiye bağlı hiperkalsemi tespit edilen ve paratiroid sintigrafisi ile tiroid lojunun sağ alt kesiminde tek paratiroid adenomu saptanan 12 yaşındaki erkek olgu sunulmuştur.
References
- Kollars J, Zarroug AE, Heerden JV, Lteif A, Stavlo P, et al. Primary hyperparathyroidism in pediatric patients. Pediatrics 2005;115:974.
- George J, Acharya SV, Bandgar TR, Menon PS, Shah NS. Primary hyperparathyroidism in children and adolescents. Indian J Pediatr 2010;77:175-8.
- Lietman SA, Germain-Lee EL, Levine MA. Hypercalcemia in children and adolescents. Curr Opin Pediatr 2010;22:508-15.
- Simsek E, Arikan Y, Dallar Y, Akkus MA. Prolonged hungry bone syndrome in a 10-year-old child with parathyroid adenoma. Indian Pediatr 2009;46:178-80.
- Atabek ME, Pirgon O, Sert A, Esen HH. Extensive brown tumors caused by parathyroid adenoma in an adolescent patient. Eur J Pediatr 2008;167:117-9.
- Brachet C, Boros E, Tenoutasse S, Lissens W, Andry G, et al. Association of parathyroid adenoma and familial hypocalciuric hypercalcaemia in a teenager. Eur J Endocrinol 2009;161:207-10.
- Egan AM, Ryan J, Aziz MA, O’Dwyer TP, Byrne MM. Primary hyperparathyroidism in a patient with familial hypocalciuric hypercalcaemia due to a novel mutation in the calcium-sensing receptor gene. J Bone Miner Metab 2013;31:477-80.
- Li CC, Yang C, Wang S, Zhang J, Kong XR, et al. A 10-year retrospective study of primary hyperparathyroidism in children. Exp Clin Endocrinol Diabetes 2012;120:229-33.
- Benaderet AD, Burton AM, Clifton-Bligh R, Ashraf AP. Primary hyperparathyroidism with low intact pth levels in a 14-year-old girl. J Clin Endocrinol Metab 2011;96:2325-9.
- Dijkstra B, Healy C, Kelly LM, Mcdermott EW, Hill ADK, et al. Parathyroid localisation-current practice. J R Coll Surg Edinb 2002:47:599-607.
Abstract
Hyperparathyroidism is very rare disorder in childhood. Patients usually present with non-specifi c symptoms such as nausea, vomiting, constipation, irritability, lethargy, headache, polyuria and polydipsia, and the diagnosis can therefore be delayed. Diagnosis is made by clinical examination and laboratory fi ndings. Parathyroid hyperplasia and adenomas can be differentiated with imaging methods. Hypocalciuric hypercalcemia may have similar fi ndings and investigating urine calcium levels is important for the differential diagnosis. Defi nitive treatment of a parathyroid adenoma is removal of the adenoma. End organ damage such as bone changes and nephrocalcinosis should be kept in mind. We discuss a 12-year-old boy who had hypercalcemia due to hyperparathyroidism. He presented at our emergency department because of nausea and vomiting and was diagnosed with a solitary parathyroid adenoma located on the lower right side of the thyroid gland by using parathyroid scintigraphy
References
- Kollars J, Zarroug AE, Heerden JV, Lteif A, Stavlo P, et al. Primary hyperparathyroidism in pediatric patients. Pediatrics 2005;115:974.
- George J, Acharya SV, Bandgar TR, Menon PS, Shah NS. Primary hyperparathyroidism in children and adolescents. Indian J Pediatr 2010;77:175-8.
- Lietman SA, Germain-Lee EL, Levine MA. Hypercalcemia in children and adolescents. Curr Opin Pediatr 2010;22:508-15.
- Simsek E, Arikan Y, Dallar Y, Akkus MA. Prolonged hungry bone syndrome in a 10-year-old child with parathyroid adenoma. Indian Pediatr 2009;46:178-80.
- Atabek ME, Pirgon O, Sert A, Esen HH. Extensive brown tumors caused by parathyroid adenoma in an adolescent patient. Eur J Pediatr 2008;167:117-9.
- Brachet C, Boros E, Tenoutasse S, Lissens W, Andry G, et al. Association of parathyroid adenoma and familial hypocalciuric hypercalcaemia in a teenager. Eur J Endocrinol 2009;161:207-10.
- Egan AM, Ryan J, Aziz MA, O’Dwyer TP, Byrne MM. Primary hyperparathyroidism in a patient with familial hypocalciuric hypercalcaemia due to a novel mutation in the calcium-sensing receptor gene. J Bone Miner Metab 2013;31:477-80.
- Li CC, Yang C, Wang S, Zhang J, Kong XR, et al. A 10-year retrospective study of primary hyperparathyroidism in children. Exp Clin Endocrinol Diabetes 2012;120:229-33.
- Benaderet AD, Burton AM, Clifton-Bligh R, Ashraf AP. Primary hyperparathyroidism with low intact pth levels in a 14-year-old girl. J Clin Endocrinol Metab 2011;96:2325-9.
- Dijkstra B, Healy C, Kelly LM, Mcdermott EW, Hill ADK, et al. Parathyroid localisation-current practice. J R Coll Surg Edinb 2002:47:599-607.
Details
| Other ID | JA49FT82GH |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 1, 2015 |
| Submission Date | April 1, 2015 |
| Published in Issue | Year 2015 Volume: 9 Issue: 1 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
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