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Adenoid Hipertrofisi Bulunan Çocuklarda Semptomatoloji ve İmmünglobulin Düzeyleri

Year 2011, Volume: 5 Issue: 2, 69 - 74, 01.08.2011

Abstract

Giriş ve amaç: Çalışmanın amacı, adenoid hipertrofisi tespit edilen çocuklarda semptomların ve immünglobulin düzeylerinin belirlenmesi.Gereç ve yöntemler: Çalışmaya, 4-15 yaş arası adenoid hipertrofisi tespit edilen 25 hasta alındı. Adenoid hipertrofisini düşündüren semptomlar belirlendi ve her vakanın lateral yan kafa grafisi çekilerek adenoid/nazofarenks oranı yüzde olarak değerlendirildi. Hastaların serum immünglobulin düzeyleri belirlendi.Bulgular: 2 vakada uyku apnesi saptanırken 8 vakada seröz otit veya sık otit geçirme öyküsü vardı. Tüm vakalarda gece ağzı açık uyuma ve sık üst solunum yolu enfeksiyonu geçirme öyküsü saptandı. 12 vakada immünglobulin düzeylerinde düşüklük tespit edilirken 3 vakanın IgE değerlerinde yükseklik saptandı.Sonuçlar: Adenoid hipertrofisi tespit edilen vakaların, olası bir immünglobulin düşüklüğü nedeniyle tedavi öncesinde serum değerleri kontrol edilmeli ve tedavi planı buna göre düzenlenmelidir.

References

  • Brandtzaeg P. Immunology of tonsils and adenoids: everything the ENT surgeon needs to know. Int J Pediatr Otorhinolaryngol 2003;67:69-76.
  • van den Akker EH, Sanders EA, van Staaij BK, Rijkers GT, Rovers MM, Hoes AW, et al. Long-term effects of pediatric adenotonsi- ilectomy on serum immunoglobulin levels: results of randomized controlled trial. Ann Allergy Asthma Immunol 2006;97(2):251-6.
  • Berlucchi M, Salsi D, Valetti L, Parrinello G, Nicolai P. The role of mometasone furoate aqueous nasal spray in the treatment of adenoi- dal hypertrophy in the pediatric age group: preliminary results of a prospective, randomized study. Pediatrics 2007; 119(6);1392-7.
  • Cengel S, Akyol MU. The role of topical nasal steroids in the treat- ment of children with otitis media with effusion and/or adenoid hypertrophy. Int J Pediatr Otorhinolaryngol 2006;70(4):639–45.
  • İkincioğulları A, Doğu F, İkincioğulları A, Eğin Y, Babacan E. Is immune system influenced by adenotonsillectomy in children? Int J Pediatr Otorhinolaryngol 2000; 66(3):251-7.
  • Bock A, Popp W, Herkner KR. Tonsillectomy and the immune sys- tem: a long term follow up comparison between tonsillectomized and nontonsillectomized children. Eur Arch Otorhinolaryngol 1994; 251(7): 423-7.
  • F Redondo, F Ventura, D Guerrero Gilabert, P Reina Garcia, D Lopez Aguada. Serum immunoglobuline levels in tonsillecto- mized patients: an unsolved mystery. Acta Otorhinolaryngol Esp 2000;51(5):403-6.
  • Tezcan I, Berkel AI, Ersoy F, Sanal O. Serum immunoglobulin levels with turbidimetric method in healthy Turkish children and adults. Turkish J Pediatr Dis 1996;39: 649-56.
  • Friday GA Jr, Paradise JL, Rabin BS, Colborn DK, Taylor FH. Serum immunoglobulin changes in relation to tonsil and adenoid surgery. Ann Allergy 1992; 69(3):225-30.
  • Moreno PM, Sanchez M, Sainz M, Gutierrez F. Changes in im- munological response in tonsillectomized children. II. Decreased cellular response. Clin Otolaryngol Allied Sci 1992;17(5):380-2.
  • Böck A, Popp W, Herkner KR. Tonsillectomy and the immune sys- tem: a long-term follow up comparison between tonsillectomized and non-tonsillectomized children. Eur Arch Otorhinolaryngol 1994;251(7):423-7.
  • Modrzyński M, Mierzwiński J, Zawisza E. The occurrence of food allergy and bacteria allergy in chiidren with tonsilar hypertrophy. Przegl Lek 2004;61(12):1330-3.
  • Demain JG, Goetz DW. Pediatric adenoidal hypertrophy and nasal airway obstruction: reduction with aqueous nasal beclomethasone. Pediatrics 1995;95(3):355–64.
  • Zhang L, Mendoza-Sassi R, César JA, Chadha NK. Intranasal cor- ticosteroids for nasal airway obstruction in children with moder- ate to severe adenoidal hypertrophy. Cochrane Database Syst Rev 2008;16(3):6286.

THE SYMPTOMS IN CHILDREN WITH ADENOIDAL HYPERTROPHY AND IMMUNOGLOBULIN LEVELS

Year 2011, Volume: 5 Issue: 2, 69 - 74, 01.08.2011

Abstract

Introduction and aim: The aim of the study is to determine the serum immunuglobulin levels and symptoms in the patients with adenoidal hypertrophy.Materials and methods: The study was included 25 patients between 4-15 ages who were detected adenoidal hypertrophy. The symtoms associated with adenoidal hypertrophy were determinated and the lateral head radiography was obtained from each patient to calculate the adenoid/nasopharyngeal ratio. The immunoglobulin levels of the patients were analyzed Results: Sleep apnea was confirmed in 2 cases, while histories of serous otitis or recurrent otitis were determined in 8 patients. The histories of open-mouth sleeping and recurrent upper-airway infectious were obtained in all patients. Decreased serum immonoglobulin levels were detected in 12 patients while elevated IgE levels were determined in 3 patients. Conclusion: In the cases that adenoidal hypertrophy was detected, because of the probable immunoglobulin lowness, serum immunoglobulin levels must be evaluated before the treatment and than the treatment strategies should be prepared

References

  • Brandtzaeg P. Immunology of tonsils and adenoids: everything the ENT surgeon needs to know. Int J Pediatr Otorhinolaryngol 2003;67:69-76.
  • van den Akker EH, Sanders EA, van Staaij BK, Rijkers GT, Rovers MM, Hoes AW, et al. Long-term effects of pediatric adenotonsi- ilectomy on serum immunoglobulin levels: results of randomized controlled trial. Ann Allergy Asthma Immunol 2006;97(2):251-6.
  • Berlucchi M, Salsi D, Valetti L, Parrinello G, Nicolai P. The role of mometasone furoate aqueous nasal spray in the treatment of adenoi- dal hypertrophy in the pediatric age group: preliminary results of a prospective, randomized study. Pediatrics 2007; 119(6);1392-7.
  • Cengel S, Akyol MU. The role of topical nasal steroids in the treat- ment of children with otitis media with effusion and/or adenoid hypertrophy. Int J Pediatr Otorhinolaryngol 2006;70(4):639–45.
  • İkincioğulları A, Doğu F, İkincioğulları A, Eğin Y, Babacan E. Is immune system influenced by adenotonsillectomy in children? Int J Pediatr Otorhinolaryngol 2000; 66(3):251-7.
  • Bock A, Popp W, Herkner KR. Tonsillectomy and the immune sys- tem: a long term follow up comparison between tonsillectomized and nontonsillectomized children. Eur Arch Otorhinolaryngol 1994; 251(7): 423-7.
  • F Redondo, F Ventura, D Guerrero Gilabert, P Reina Garcia, D Lopez Aguada. Serum immunoglobuline levels in tonsillecto- mized patients: an unsolved mystery. Acta Otorhinolaryngol Esp 2000;51(5):403-6.
  • Tezcan I, Berkel AI, Ersoy F, Sanal O. Serum immunoglobulin levels with turbidimetric method in healthy Turkish children and adults. Turkish J Pediatr Dis 1996;39: 649-56.
  • Friday GA Jr, Paradise JL, Rabin BS, Colborn DK, Taylor FH. Serum immunoglobulin changes in relation to tonsil and adenoid surgery. Ann Allergy 1992; 69(3):225-30.
  • Moreno PM, Sanchez M, Sainz M, Gutierrez F. Changes in im- munological response in tonsillectomized children. II. Decreased cellular response. Clin Otolaryngol Allied Sci 1992;17(5):380-2.
  • Böck A, Popp W, Herkner KR. Tonsillectomy and the immune sys- tem: a long-term follow up comparison between tonsillectomized and non-tonsillectomized children. Eur Arch Otorhinolaryngol 1994;251(7):423-7.
  • Modrzyński M, Mierzwiński J, Zawisza E. The occurrence of food allergy and bacteria allergy in chiidren with tonsilar hypertrophy. Przegl Lek 2004;61(12):1330-3.
  • Demain JG, Goetz DW. Pediatric adenoidal hypertrophy and nasal airway obstruction: reduction with aqueous nasal beclomethasone. Pediatrics 1995;95(3):355–64.
  • Zhang L, Mendoza-Sassi R, César JA, Chadha NK. Intranasal cor- ticosteroids for nasal airway obstruction in children with moder- ate to severe adenoidal hypertrophy. Cochrane Database Syst Rev 2008;16(3):6286.
There are 14 citations in total.

Details

Other ID JA96EF72FH
Journal Section Research Article
Authors

Hayrullah Alp This is me

Publication Date August 1, 2011
Submission Date August 1, 2011
Published in Issue Year 2011 Volume: 5 Issue: 2

Cite

Vancouver Alp H. THE SYMPTOMS IN CHILDREN WITH ADENOIDAL HYPERTROPHY AND IMMUNOGLOBULIN LEVELS. Türkiye Çocuk Hast Derg. 2011;5(2):69-74.


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