Abstract
Peliosis hepatis karaciğerin değişik etiyolojik faktörler ve farklı patogenetik mekanizmalara bağlı olarak gelişen nadir bir vasküler hastalığıdır. Kemik iliği yetmezliği sendromlarında sıklıkla kullanılan androjenler nadiren peliosis hepatise neden olabilirler. Biz Fanconi aplastik anemi tanısı ile 4 yıldır androjen kullanan ve peliosis hepatis gelişen bir olguyu sunduk.
Keywords
References
- Velazquez I, Alter BP. Androgen and liver tumors: Fanconi’s anemia and non-Fanconi’s conditions. Am J Hematol 2004; 77:257-267
- Cavalcanti R, Pol S, Carton F, Campos H, Degott C, Driss F, Legendre C, Kreis H. Impact and evolution of peliosis hepatis in renal transplant recipients. Transplantation 1994; 58:315-316.
- Ahsan N, Holman MJ, Riley TR, Abendroth CS, Langhoff EG, Yang HC. Peloisis hepatis due to Bartonella henselae in transplantation: a hemato- hepato - renal syndrome. Transplantation 1998;65:1000-1003.
- Nadell J, Kosek J. Peliosis hepatis. Twelve cases associated with oral androgen therapy. Arch Pathol Lab Med 1977;101:405-410.
- Arnold GL, Kaplan MM. Peliosis heoatis due to oxymetholone - a clinically benign disorder. Am J Gastroenterol, 1979; 71:213-216.
- Tsirigotis P, Sella T, Shapira MY, Bitan M, Bloom A, Kiselgoff D, Levin M, Libster D, Abdul Hai A, Gesundheit B, Or R, Slavin S, Resnick I. Peliosis hepatis following treatment with androgen-steroids in patients with bone marrow failure syndromes. Haematologica. 2007;92:106-110.
- Vignaux O, Legmann P, de Pinieux G, Chaussade S, Spaulding C, Couturier D, Bonnin A. Hemorrhagic necrosis due to peliosis hepatis: imaging findings and pathological correlation. Eur Radiol 1999;9:454-456.
- Jacquermin E, Pariente D, Fabre M, Huault G, Valayer J, Bernard O. Peliosis hepatis with initial presentation as acute hepatic failure and intraperitoneal hemorrhage in children. J Hepatol 1999; 30:1146-1150.
- Warfel KA, Ellis GH. Peliosis of the spleen. Report of a case and review of the literature. Arch Pathol Lab Med 1982;106:99-100.
- Gouya H, Vignaux O, Legmann P, de Pigneux G, Bonnin A. Peliosis hepatis: triphasic helical CT and dynamic MRI findings. Abdom Imaging 2001; 26:507–509.
Abstract
Peliosis hepatis (PH) is an uncommon vascular disorder of the liver that may be caused by several etiologic agents and different pathogenetic mechanisms. Androgens which are widely used in the treatment of bone marrow failure syndromes can cause hepatic peliosis in rare cases. We describe a case of Fanconi aplastic anaemia in which PH developed after 4 years of treatment with androgens
Keywords
References
- Velazquez I, Alter BP. Androgen and liver tumors: Fanconi’s anemia and non-Fanconi’s conditions. Am J Hematol 2004; 77:257-267
- Cavalcanti R, Pol S, Carton F, Campos H, Degott C, Driss F, Legendre C, Kreis H. Impact and evolution of peliosis hepatis in renal transplant recipients. Transplantation 1994; 58:315-316.
- Ahsan N, Holman MJ, Riley TR, Abendroth CS, Langhoff EG, Yang HC. Peloisis hepatis due to Bartonella henselae in transplantation: a hemato- hepato - renal syndrome. Transplantation 1998;65:1000-1003.
- Nadell J, Kosek J. Peliosis hepatis. Twelve cases associated with oral androgen therapy. Arch Pathol Lab Med 1977;101:405-410.
- Arnold GL, Kaplan MM. Peliosis heoatis due to oxymetholone - a clinically benign disorder. Am J Gastroenterol, 1979; 71:213-216.
- Tsirigotis P, Sella T, Shapira MY, Bitan M, Bloom A, Kiselgoff D, Levin M, Libster D, Abdul Hai A, Gesundheit B, Or R, Slavin S, Resnick I. Peliosis hepatis following treatment with androgen-steroids in patients with bone marrow failure syndromes. Haematologica. 2007;92:106-110.
- Vignaux O, Legmann P, de Pinieux G, Chaussade S, Spaulding C, Couturier D, Bonnin A. Hemorrhagic necrosis due to peliosis hepatis: imaging findings and pathological correlation. Eur Radiol 1999;9:454-456.
- Jacquermin E, Pariente D, Fabre M, Huault G, Valayer J, Bernard O. Peliosis hepatis with initial presentation as acute hepatic failure and intraperitoneal hemorrhage in children. J Hepatol 1999; 30:1146-1150.
- Warfel KA, Ellis GH. Peliosis of the spleen. Report of a case and review of the literature. Arch Pathol Lab Med 1982;106:99-100.
- Gouya H, Vignaux O, Legmann P, de Pigneux G, Bonnin A. Peliosis hepatis: triphasic helical CT and dynamic MRI findings. Abdom Imaging 2001; 26:507–509.
Details
| Other ID | JA49ZA42VP |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | June 1, 2010 |
| Submission Date | June 1, 2010 |
| Published in Issue | Year 2010 Volume: 4 Issue: 3 |
The publication language of Turkish Journal of Pediatric Disease is English.
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