BibTex RIS Cite

Açıklanamayan Transaminaz Yüksekliği ve Atipik Çölyak Hastalığı: Olgu Sunumu

Year 2008, Volume: 2 Issue: 2, 33 - 38, 01.06.2008

Abstract

Çölyak hastalığı transaminaz yüksekliğinin önemli nedenlerinden birisidir. Açıklanamayan transaminaz yüksekliği olan hastaların % 9'unda çölyak hastalığı saptandığı bildirilmiştir. Başka bir bulgusu olmaksızın 6 aydır devam eden transaminaz yüksekliği nedeniyle tetkik edilirken çölyak hastalığı tanısı alan ve glutensiz diyet başlandıktan 6 ay sonra transaminaz yüksekliği normale dönen, bir çocuk hasta sunulmuştur.

References

  • Farre C, Esteve M, Curcoy A, Cabre E, Arranz E, Amat LL, Garcia- Tornel S. Hypertransaminasemia in pediatric coeliac disease and its prevalance as a diagnostic clue. Am J Gastroenterol 2002;97:3176-3181.
  • Ludvigsson JF, Elfström P, Broome U, Ekbom A, Montgomery SM. Celiac disease and risk of liver disease: a general population-based study. Clin Gastroenterol Hepatol 2007;5:63-69.
  • Kaukinen K, Hamle L, Collin P, Farkkıla M, Maki M, Vehmanen P, Partanen J, Höckerstedt K. Celiac disease in patients with severe liver disease: gluten free diet may reverse hepatic failure. Gastroenterology 2002;122:881-888.
  • Volta U, de Franceschi L, Molinaro N, Cassani F, Muratori L, Lenzi M, Bianchi FB, Czaja AJ. Frequency and significance antigliadin and antiendomysial antibodies in autoimmune hepatitis. Dig Dis Sci 1998;43:2190-2195.
  • Jacobsen MB, Fausa O, Elgjo K, Schrumpf E. Hepatic lesions in adult coeliac disease. Scand J Gastroenterol 1990;25:656-662.
  • Greco L, Auricchio S, Mayer M, Grimaldi M. Case-control study on nutritional risk factors in celiac disease. J Pediatr Gatroenterol Nutr 1988;7:395-399.
  • Peters U, Schneeweiss S, Trautwein EA, Erbersdobler HF. A case- control study of the effcet of infant feeding on coeliac disese. Ann Nutr Metab 2001;45:135-142.
  • Auricchio S, Follo D, de Ritis G, Giunta A, Marzorati D, Prampolini L, Ansaldi N, Levi P, Dall'olio D, Bossi A, et all. Does brestfeeding protect against the development of clinical symptoms of coeliac disease in children. J Pediatr Gastroenterol Nutr 1983;2:428-433.
  • Falth-Magnusson K, Franzen L, Jansson G, Laurin P, Stenhammar L. Infant feeding history shows distinct differences between Swedish celiac and reference children. Pediatr Allergy Immunol 1996;7:1-5.
  • Ascher H, Krantz I, Rydberg L, Nordin P, Kristiansson. Influence of infant feeding and gluten intake on coeliac disease. Arch Dis Child 1997;76:113-117.
  • Akobeng AK, Ramanan AV, Buchan I, Heller RF. Effect of breastfeeding on coeliac disease: a sytematic review and meta-analysis of observational study. Arch Dis Child 2006;91:39-43.
  • Novacek G, Miehsler W, Wrba F, Ferenci P, Penner E, Vogelsang H.
  • Arslan N, Büyükgebiz B, Öztürk Y, Özer E. The prevalance of liver function abnormalities in pediatric celiac disease patients and its relation with intestinal biopsy findings. Acta Gastroenterol Belg 2005;68:424-427.

UNEXPLAINED ELEVATION OF SERUM TRANSAMINASE LEVEL AND ATYPICAL CELIAC DISEASE: A CASE REPORT

Year 2008, Volume: 2 Issue: 2, 33 - 38, 01.06.2008

Abstract

Celiac disease is an important cause of hypertransaminasemia. Celiac disease has been reported in 9 % of patients with unexplained hypertransaminasemia. We report a child who presented with elevated serum transaminase activity, and diagnosed as celiac disease after exclusion of other causes of chronic hypretransaminasemia. Hypertransaminasemia improved after 6 months of gluten free diet

References

  • Farre C, Esteve M, Curcoy A, Cabre E, Arranz E, Amat LL, Garcia- Tornel S. Hypertransaminasemia in pediatric coeliac disease and its prevalance as a diagnostic clue. Am J Gastroenterol 2002;97:3176-3181.
  • Ludvigsson JF, Elfström P, Broome U, Ekbom A, Montgomery SM. Celiac disease and risk of liver disease: a general population-based study. Clin Gastroenterol Hepatol 2007;5:63-69.
  • Kaukinen K, Hamle L, Collin P, Farkkıla M, Maki M, Vehmanen P, Partanen J, Höckerstedt K. Celiac disease in patients with severe liver disease: gluten free diet may reverse hepatic failure. Gastroenterology 2002;122:881-888.
  • Volta U, de Franceschi L, Molinaro N, Cassani F, Muratori L, Lenzi M, Bianchi FB, Czaja AJ. Frequency and significance antigliadin and antiendomysial antibodies in autoimmune hepatitis. Dig Dis Sci 1998;43:2190-2195.
  • Jacobsen MB, Fausa O, Elgjo K, Schrumpf E. Hepatic lesions in adult coeliac disease. Scand J Gastroenterol 1990;25:656-662.
  • Greco L, Auricchio S, Mayer M, Grimaldi M. Case-control study on nutritional risk factors in celiac disease. J Pediatr Gatroenterol Nutr 1988;7:395-399.
  • Peters U, Schneeweiss S, Trautwein EA, Erbersdobler HF. A case- control study of the effcet of infant feeding on coeliac disese. Ann Nutr Metab 2001;45:135-142.
  • Auricchio S, Follo D, de Ritis G, Giunta A, Marzorati D, Prampolini L, Ansaldi N, Levi P, Dall'olio D, Bossi A, et all. Does brestfeeding protect against the development of clinical symptoms of coeliac disease in children. J Pediatr Gastroenterol Nutr 1983;2:428-433.
  • Falth-Magnusson K, Franzen L, Jansson G, Laurin P, Stenhammar L. Infant feeding history shows distinct differences between Swedish celiac and reference children. Pediatr Allergy Immunol 1996;7:1-5.
  • Ascher H, Krantz I, Rydberg L, Nordin P, Kristiansson. Influence of infant feeding and gluten intake on coeliac disease. Arch Dis Child 1997;76:113-117.
  • Akobeng AK, Ramanan AV, Buchan I, Heller RF. Effect of breastfeeding on coeliac disease: a sytematic review and meta-analysis of observational study. Arch Dis Child 2006;91:39-43.
  • Novacek G, Miehsler W, Wrba F, Ferenci P, Penner E, Vogelsang H.
  • Arslan N, Büyükgebiz B, Öztürk Y, Özer E. The prevalance of liver function abnormalities in pediatric celiac disease patients and its relation with intestinal biopsy findings. Acta Gastroenterol Belg 2005;68:424-427.
There are 13 citations in total.

Details

Other ID JA54VN39BR
Journal Section Research Article
Authors

Zarife Kuloğlu This is me

Ceyda Tuna Kırsaçlıoğlu This is me

Aydan Kansu This is me

Arzu Ensari This is me

Nurten Girgin This is me

Publication Date June 1, 2008
Submission Date June 1, 2008
Published in Issue Year 2008 Volume: 2 Issue: 2

Cite

Vancouver Kuloğlu Z, Kırsaçlıoğlu CT, Kansu A, Ensari A, Girgin N. UNEXPLAINED ELEVATION OF SERUM TRANSAMINASE LEVEL AND ATYPICAL CELIAC DISEASE: A CASE REPORT. Türkiye Çocuk Hast Derg. 2008;2(2):33-8.


The publication language of Turkish Journal of Pediatric Disease is English.


Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.


The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.