Abstract
Kortikosteroidler, glomerüler nefropatilerde ve böbrek transplantasyonunda yaygın olarak kullanılmaktadır. Steroidlerin uzun süreli kullanımına bağlı olarak ciddi yan etkiler görülmektedir. Diyabetik ketoasidoztablosu nadiren bildirilmektedir. Burada, Fokal Segmental Glomeruloskleroz nedeniyle yüksek doz steroid kullanırken diyabetik ketoasidozis gelişen ve steroid dozu azaltıldığında kan şekeri düzelen hasta sunulmuştur.
References
- 1. YoshiW. EM, Buczkowski AK. Sim SM, Elliott TG, Scudaınore CH, Lcvin A, Tıldesley HD, Landsberg DN. Post-transplant diabetic ketoacidosis-ıı. possible coruıequcnce of immunosuppression with calcineurininhibitingagents. Tn.nsp1Iııt2000; 13: 69-72.
- 2. Kcshııvarz R, Mousavi M, Hassan C. Diabetic ketoacidosis in a child on FK506 immunosuppression arter a liver transplıınt. Pediatr Emerg Can: 2002; 18: 22-24.
- 3. Erııoy A, Ersoy C, Tekce H, YAVa.Scııoglu 1, Dilek K. Dia.betic ketoacidosis following devclopment of de nova diabetes in tenal transplant recipient associated with tııcrolimus. Transplıınt Proc 2004;36: 1407-1410.
- 4. Toyonaga T, Kondo T,Miyamura N, Selrigami T, Sonoda K, Kodama S, Shinıkami A. Shİ1'otani T, Anki E. Sudden onset of diabetes with ketoacidosis in a patlent treated with FK506/tacrolimus. Diabetes fu:s Clin Ptact2002; 56:13-18.
- 5. www.mdcoruıult.com (Cyclosporine, tacrolimus adverse reactions. MDConsult,Drugs).
- 6. O~ Kaya.alp. Tıbbi Farmakoloji Rasyonel Tedavi Yönünden. Ankara: Hacettepe-Taş Kitapçılık, 11. Baskı, 2005: 1000-1100.
- 7. Bernatd Schimmeı BP, Parke.r KL. Adenocoıticottopic hormone.In:Phannacologic basis of therapeutic. Hardınan JG, limited LE, 9tb. ed NewYork,Mc GmwHill İne, 1996; 1459-1486.
- 8. David-Neto E, Lemos FC, Fa.del LM, Agena F, Sata MY, Coccuza. C, Percira LM, de Castto MC, Lando VS, Nahas WC, Ianhcz LE. The dynamics of glucose metabolism under calcineurin inhibitors in the first year aftcr renal transplantatlon in nonobcsc patients. Transplııntatlon 2007; 84: 50-55.
- 9. Dundar B, Eren E, Oktern F, Dundar N, Tunc B, Canatan n Hyperosmolar non-ketotlc sytıdrome in a child associated with 1-ıı.sparaginase and prednisolone. Pediatt lnt 2007; 49: 256-257.
- 10. Yang JY, Cui XL, He XJ Non-ketotlc hyperosmolar coma complicatlng steroid trea.tment in dıildhood nephrosis. Pediatr Nephrol 1995;9:621-622.
- 11. Yoshioka K, Sa.ta T, Okada N, Ishii T, Imanishi M, Tanaka S, Kim T, Sugimoto T, Fujii S. Post-transplant diabetes with anti-glut:atnic acid decarboxykse antibody during tacrolimus therapy. Dia.bet.es Res Oin Ptact1998;42: 85-89.
- 12. Agarwall DK, Jeloka T, Sharma AP, Sharma RK. Steroid induccd diabetes mellitus prescntingas diabctic ketoacidosis. Indian J.Ncphrol 2002; 12: 122-123.
- 13. Iw.unoto T, Kagawa Y, Naito Y, Kuzuhııra S, Kojima M. Steroid induced diabetes mellituıı anıl re.la.ted risk fiı.ctors in patients with neurologic discases. Phatmacothctapy 2004; 24: 508-514.
- 14. Banac S, PcrsiC M, Cvijovic K. Steroid diabetes in childrcn with Crohn disease. ActaMed Croatica2002; 56: 35-38.
- 15. SpearML,Rceves G, Pearlman SA. Diabetic lretoacidosis after steroid administtation for bronchopulmonuydysplasia J Peı:inatol 1993; 13: 232-234.
Abstract
Corticosteroids are commonly used drugs in the treatment of glomerular diseases and renal posttransplantation management. However, long-term use of systemic corticosteroids have substantial
side effects. The association of diabetic ketoacidosis with the use of systemic corticosteroids is
infrequently reported. We report a complication of diabetic ketoacidosis, associated with the use
of high dose corticosteroid for the treatment of focal segmental glomerulosclerosis; which
improved afterthe cessation of steroid therapy.
References
- 1. YoshiW. EM, Buczkowski AK. Sim SM, Elliott TG, Scudaınore CH, Lcvin A, Tıldesley HD, Landsberg DN. Post-transplant diabetic ketoacidosis-ıı. possible coruıequcnce of immunosuppression with calcineurininhibitingagents. Tn.nsp1Iııt2000; 13: 69-72.
- 2. Kcshııvarz R, Mousavi M, Hassan C. Diabetic ketoacidosis in a child on FK506 immunosuppression arter a liver transplıınt. Pediatr Emerg Can: 2002; 18: 22-24.
- 3. Erııoy A, Ersoy C, Tekce H, YAVa.Scııoglu 1, Dilek K. Dia.betic ketoacidosis following devclopment of de nova diabetes in tenal transplant recipient associated with tııcrolimus. Transplıınt Proc 2004;36: 1407-1410.
- 4. Toyonaga T, Kondo T,Miyamura N, Selrigami T, Sonoda K, Kodama S, Shinıkami A. Shİ1'otani T, Anki E. Sudden onset of diabetes with ketoacidosis in a patlent treated with FK506/tacrolimus. Diabetes fu:s Clin Ptact2002; 56:13-18.
- 5. www.mdcoruıult.com (Cyclosporine, tacrolimus adverse reactions. MDConsult,Drugs).
- 6. O~ Kaya.alp. Tıbbi Farmakoloji Rasyonel Tedavi Yönünden. Ankara: Hacettepe-Taş Kitapçılık, 11. Baskı, 2005: 1000-1100.
- 7. Bernatd Schimmeı BP, Parke.r KL. Adenocoıticottopic hormone.In:Phannacologic basis of therapeutic. Hardınan JG, limited LE, 9tb. ed NewYork,Mc GmwHill İne, 1996; 1459-1486.
- 8. David-Neto E, Lemos FC, Fa.del LM, Agena F, Sata MY, Coccuza. C, Percira LM, de Castto MC, Lando VS, Nahas WC, Ianhcz LE. The dynamics of glucose metabolism under calcineurin inhibitors in the first year aftcr renal transplantatlon in nonobcsc patients. Transplııntatlon 2007; 84: 50-55.
- 9. Dundar B, Eren E, Oktern F, Dundar N, Tunc B, Canatan n Hyperosmolar non-ketotlc sytıdrome in a child associated with 1-ıı.sparaginase and prednisolone. Pediatt lnt 2007; 49: 256-257.
- 10. Yang JY, Cui XL, He XJ Non-ketotlc hyperosmolar coma complicatlng steroid trea.tment in dıildhood nephrosis. Pediatr Nephrol 1995;9:621-622.
- 11. Yoshioka K, Sa.ta T, Okada N, Ishii T, Imanishi M, Tanaka S, Kim T, Sugimoto T, Fujii S. Post-transplant diabetes with anti-glut:atnic acid decarboxykse antibody during tacrolimus therapy. Dia.bet.es Res Oin Ptact1998;42: 85-89.
- 12. Agarwall DK, Jeloka T, Sharma AP, Sharma RK. Steroid induccd diabetes mellitus prescntingas diabctic ketoacidosis. Indian J.Ncphrol 2002; 12: 122-123.
- 13. Iw.unoto T, Kagawa Y, Naito Y, Kuzuhııra S, Kojima M. Steroid induced diabetes mellituıı anıl re.la.ted risk fiı.ctors in patients with neurologic discases. Phatmacothctapy 2004; 24: 508-514.
- 14. Banac S, PcrsiC M, Cvijovic K. Steroid diabetes in childrcn with Crohn disease. ActaMed Croatica2002; 56: 35-38.
- 15. SpearML,Rceves G, Pearlman SA. Diabetic lretoacidosis after steroid administtation for bronchopulmonuydysplasia J Peı:inatol 1993; 13: 232-234.
Details
| Other ID | JA34DY47TC |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | April 1, 2008 |
| Submission Date | April 1, 2008 |
| Published in Issue | Year 2008 Volume: 2 Issue: 3 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.