Abstract
Amaç: Kawasaki Hastalığı (KH) tanısı ile izlenen olgularımızın tipik ve atipik klinik özelliklerinin tespit edilmesi amaçlanmıştır.
Gereç ve Yöntemler: Ekim 2014 - Mayıs 2017 tarihleri arasında KH tanısıyla izlenen hastalar çalışmaya dahil edilmiştir.
Hastaların tanısı American Heart Association (AHA) tanı kriterlerine göre konulmuştur.
Bulgular: Çalışmamıza KH tanılı 19 hasta dahil edildi. Ortalama yaş 33±20 aydı. 16 hasta (%84) erkek, 3 hasta (%16)
kızdı. Hastalığın en sık görüldüğü mevsim kış (n=6, % 31.5) ve sonbahar (n=6,%31.5)’di. Ateşe eşlik eden en sık şikayet
17 (%89) hastada görülen döküntüydü. Hastaların 2’inde pürülan konjunktivit, 2’inde ise süpüratif lenfadenopati gibi
atipik bulgular gözlendi. Özellikle inkomplet olgularda tanı için önemli olan destekleyici laboratuvar bulgularından trombositoz
hastaların %100’ünde 11.5±2.4. günde tespit edildi. Koroner arter tutulum oranı yüksek olup hastaların %47’inde
pozitifti. İntravenöz immünglobulin (IVIG) ve asetil salisilik asit (ASA) tedavisi ile koroner tutulumlarda gerileme gözlenirken
bir hastamızda başlangıçta koroner tutulum olmamasına rağmen 2 yıl sonra anevrizma oluşumu tespit edildi.
Sonuç: Ülkemizde KH’ında koroner arter tutulumu literatüre göre daha sık görülmektedir. KH pürülan konjunktivit, süpüratif
lenfadenit gibi ayırıcı tanıda zorluk oluşturan atipik bulgular görülebilmektedir. Böyle hastalarda da etkin tedavi için
eklenecek klinik ve destekleyici laboratuvar bulgularına dikkat edilmelidir. Hastalardaki bu farklılıkların aydınlatılabilmesi
için genetik ve etiyolojik çalışmalara önem verilmelidir. Hastaların izlemi yeni oluşacak anevrizmaların tespiti açısından
oldukça önemlidir.
Keywords
References
- 1. McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, et al. Diagnosis, treatment, and long-term management of kawasaki disease: A scientific statement for health professionals from the american heart association. Circulation 2017;135: e927-e999.
- 2. Lloyd AJ, Walker C, Wilkinson M. Kawasaki disease: Is it caused by an infectious agent? Br J Biomed Sci 2001;58:112-28.
- 3. Takahashi M, Newburger JW. Kawasaki Disease, In: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, (eds). Moss and Adams' Heart Disease in Infants, Children, and Adolescents Including the Fetus and Young Adult. 7th ed. Philedelphia: Lippincott Williams & Wilkins 2008; 1242-56.
- 4. Furusho K, Kamiya T, Nakano H, Kiyosawa N, Shinomiya K, Hayashidera T, et al. High-dose intravenous gammaglobulin for Kawasaki disease. Lancet 1984; 2: 1055-8.
- 5. Newburger J. Kawasaki Disease, In: Andersen RH, Baker EJ, Penny D, Redington AN, Michael LR, Wernowsky G (eds). Paediatric Cardiology. 3rd ed. Philedelphia: Churchill Livingstone Elsevier 2010; 1067-78.
- 6. Burns JC, Glodé MP. Kawasaki syndrome. Lancet 2004; 364: 533- 44.
Abstract
References
- 1. McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, et al. Diagnosis, treatment, and long-term management of kawasaki disease: A scientific statement for health professionals from the american heart association. Circulation 2017;135: e927-e999.
- 2. Lloyd AJ, Walker C, Wilkinson M. Kawasaki disease: Is it caused by an infectious agent? Br J Biomed Sci 2001;58:112-28.
- 3. Takahashi M, Newburger JW. Kawasaki Disease, In: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, (eds). Moss and Adams' Heart Disease in Infants, Children, and Adolescents Including the Fetus and Young Adult. 7th ed. Philedelphia: Lippincott Williams & Wilkins 2008; 1242-56.
- 4. Furusho K, Kamiya T, Nakano H, Kiyosawa N, Shinomiya K, Hayashidera T, et al. High-dose intravenous gammaglobulin for Kawasaki disease. Lancet 1984; 2: 1055-8.
- 5. Newburger J. Kawasaki Disease, In: Andersen RH, Baker EJ, Penny D, Redington AN, Michael LR, Wernowsky G (eds). Paediatric Cardiology. 3rd ed. Philedelphia: Churchill Livingstone Elsevier 2010; 1067-78.
- 6. Burns JC, Glodé MP. Kawasaki syndrome. Lancet 2004; 364: 533- 44.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | ORIGINAL ARTICLES |
| Authors | |
| Publication Date | December 30, 2018 |
| Submission Date | August 3, 2017 |
| Published in Issue | Year 2018 Volume: 12 Issue: 4 |
Cited By
Kawasaki Disease: 10-year Single-center Experience: Analysis of Clinical and Laboratory Findings with Treatment Approaches
Bakirkoy Tip Dergisi / Medical Journal of Bakirkoy
https://doi.org/10.4274/BMJ.galenos.2023.2023.1-5
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