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Application of Screening Tests in Diagnosis of Gestational Diabetes Mellitus

Year 2019, Volume: 13 Issue: 6, 489 - 491, 23.12.2019
https://doi.org/10.12956/tchd.628264

Abstract

Background: Gestational
Diabetes Mellitus (GDM) is defined as the glucose intolerance started or
diagnosed first at pregnancy. GDM screening tests are applied as single or
two-step tests. The aim of the present study is to evaluate the numbers and
positiveness ratios of single or two-step screening tests.

Materials and Methods:
The number of GDM screening test pregnant women applied to Ankara Numune
training and Research Hospital Biochemistry Clinic between years 2010-2014 were
evaluated from Hospital Laboratory Information System retrospectively, and
applied numbers of one and two step screening tests and positiveness ratios
were evalauted fort his 5 year period.

Results:
281 (18,5%) of the total 1514 tests were positive. 270 (96,1%) of this positive
results were obtained by one-step test and 11 (3,9%) of them were obtained by
two-step test. In year 2011, all screening tests were carried out by one-step
approach. In years 2012-2014, single step approach was appplied in increasing
ratios. GDM detection rate of sinle-step test was found to be higher than
two-step test.










Conclusion:
Single step approach can be the test of choice for GDM screening as it has a
higher detection rate and more comfortable fort he patient.

References

  • 1. Beckmann CRB, Ling FW, Smith RP, et al., editors. Obstetrics and Gynecology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005.
  • 2. Metzger BE, Buchanan TA, Coustan DR, de Leiva A, Dung-er DB, Hadden DR, et al. Summary and recommendations of the Fi;h International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care. 2007 Jul;30:251-260.
  • 3. American College of Obstetricians and Gynecologists Committee on Practice Bulletins—Obstetrics. ACOG Practice Bulletin, authors. Clinical management guidelines for obstetrician-gynecologists. Number 30, September 2001 (replaces Technical Bulletin Number 200, December 1994). Gestational diabetes. Obstet Gynecol. 2001;98:525–538.
  • 4. Diabetes Care; Proceedings of the 4th International Workshop-Conference on Gestational Diabetes Mellitus; 14–16 March 1997; Chicago, Illinois, USA. 1998. pp. B1–B167.
  • 5. Vitacolonna E, Succurro E, Lapolla A, Scavini M, Bonomo M, Di Cianni G, Di Benedetto A, Napoli A, Tumminia A, Festa C, Lencioni C, Torlone E, Sesti G, Mannino D, Purrello F. Guidelines for the screening and diagnosis of gestational diabetes in Italy from 2010 to 2019: critical issues and the potential for improvement. Acta Diabetol. 2019 Aug 8. doi: 10.1007/s00592-019-01397-4.
  • 6. Alves DS, de Moura Ferreira Gomes MC, de Araújo Novaes M.An Obstetric Application Architecture for Information, Diagnosis and Control of Diabetes in High Risk Pregnancy. Stud Health Technol Inform. 2019 Aug 21;264:778-782. doi: 10.3233/SHTI190329
  • 7. Albrecht SS, Kuklina EV, Bansil P, Jamieson DJ, Whiteman MK, Kourtis AP, et al. Diabetes trends among delivery hospitalizations in the U.S., 1994-2004. Diabetes Care 2010;33:768-773.
  • 8. Amanda “Bird” Hoffert Gilmartin, Serdar H Ural, ohn T Repke.Gestational Diabetes Mellitus. Rev Obstet Gynecol. 2008 Summer; 1(3): 129–134.
  • 9. International Association of Diabetes and Pregnancy Study Groups Consensus Panel, Metzger BE, Gabbe SG, Persson B,Buchanan TA, Catalano PA, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classi)cation of hyperglycemia in preg-nancy. Diabetes Care. 2010 Mar;33(3):676-682

Gestasyonel Diyabetes Mellitus Tanısında Tarama Testlerinin Uygulanma Oranı

Year 2019, Volume: 13 Issue: 6, 489 - 491, 23.12.2019
https://doi.org/10.12956/tchd.628264

Abstract

Amaç: Gestasyonel
Diyabetes Mellitus (GDM), ilk defa gebelikte başlayan veya teşhis edilen glukoz
intoleransıdır.. GDM tarama testleri tek veya iki aşamalı uygulanabilmektedir. Bu
çalışmanın amacı,
, tek ve iki aşamalı tarama test sayılarının ve
pozitiflik oranlarını karşılaştırmalı olarak değerlendirmektir.

Gereç
ve yöntem:
Çalışmada 2010-2014 yılları arasında Ankara
Numune Eğitim ve Araştırma Hastanesi Tıbbi Biyokimya Kliniği’ne GDM tarama
testi için başvuran gebelere yapılan Oral Glukoz Tolerans Testi (OGTT) sayıları
HBYS üzerinden taranmış,  İki aşamalı
tarama testi (50g ve 100g) ile tek aşamalı (75g) tarama protokollerinin yıllara
göre değişen sayıları ve pozitiflik oranları 5 yıllık süreçte retrospektif
olarak incelenmiştir.

Bulgular: Yapılan
toplam 1514 testin 281’i (%18,5) pozitiftir. Pozitif sonuçların 270’i (%96,1)
tek aşamalı, 11’i (%3,9) iki aşamalı test ile elde edilmiştir.  2011 yılında tüm tarama testleri tek aşamalı
olarak yapılmıştır. 2012-2014 yıllarında tek aşamalı test giderek artan
oranlarla uygulanmıştır. Tek aşamalı testin GDM tespit oranları iki aşamalı
teste göre daha yüksek bulunmuştur.







Sonuç: Gebelerde
GDM’yi yüksek oranda saptaması ve hasta açısından daha rahat olması nedeniyle
tek aşamalı tarama testi tercih edilmelidir.

References

  • 1. Beckmann CRB, Ling FW, Smith RP, et al., editors. Obstetrics and Gynecology. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005.
  • 2. Metzger BE, Buchanan TA, Coustan DR, de Leiva A, Dung-er DB, Hadden DR, et al. Summary and recommendations of the Fi;h International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care. 2007 Jul;30:251-260.
  • 3. American College of Obstetricians and Gynecologists Committee on Practice Bulletins—Obstetrics. ACOG Practice Bulletin, authors. Clinical management guidelines for obstetrician-gynecologists. Number 30, September 2001 (replaces Technical Bulletin Number 200, December 1994). Gestational diabetes. Obstet Gynecol. 2001;98:525–538.
  • 4. Diabetes Care; Proceedings of the 4th International Workshop-Conference on Gestational Diabetes Mellitus; 14–16 March 1997; Chicago, Illinois, USA. 1998. pp. B1–B167.
  • 5. Vitacolonna E, Succurro E, Lapolla A, Scavini M, Bonomo M, Di Cianni G, Di Benedetto A, Napoli A, Tumminia A, Festa C, Lencioni C, Torlone E, Sesti G, Mannino D, Purrello F. Guidelines for the screening and diagnosis of gestational diabetes in Italy from 2010 to 2019: critical issues and the potential for improvement. Acta Diabetol. 2019 Aug 8. doi: 10.1007/s00592-019-01397-4.
  • 6. Alves DS, de Moura Ferreira Gomes MC, de Araújo Novaes M.An Obstetric Application Architecture for Information, Diagnosis and Control of Diabetes in High Risk Pregnancy. Stud Health Technol Inform. 2019 Aug 21;264:778-782. doi: 10.3233/SHTI190329
  • 7. Albrecht SS, Kuklina EV, Bansil P, Jamieson DJ, Whiteman MK, Kourtis AP, et al. Diabetes trends among delivery hospitalizations in the U.S., 1994-2004. Diabetes Care 2010;33:768-773.
  • 8. Amanda “Bird” Hoffert Gilmartin, Serdar H Ural, ohn T Repke.Gestational Diabetes Mellitus. Rev Obstet Gynecol. 2008 Summer; 1(3): 129–134.
  • 9. International Association of Diabetes and Pregnancy Study Groups Consensus Panel, Metzger BE, Gabbe SG, Persson B,Buchanan TA, Catalano PA, et al. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classi)cation of hyperglycemia in preg-nancy. Diabetes Care. 2010 Mar;33(3):676-682
There are 9 citations in total.

Details

Primary Language Turkish
Subjects ​Internal Diseases
Journal Section ORIGINAL ARTICLES
Authors

Çiğdem Yücel 0000-0003-2647-440X

Andaç Onur This is me 0000-0003-2950-2680

Sebla Ertuğrul This is me 0000-0001-6150-5385

Müjgan Ercan 0000-0002-9291-4197

Murat Kızılgün This is me 0000-0001-5551-4058

Turan Turhan 0000-0002-7316-1273

Publication Date December 23, 2019
Submission Date October 2, 2019
Published in Issue Year 2019 Volume: 13 Issue: 6

Cite

Vancouver Yücel Ç, Onur A, Ertuğrul S, Ercan M, Kızılgün M, Turhan T. Gestasyonel Diyabetes Mellitus Tanısında Tarama Testlerinin Uygulanma Oranı. Türkiye Çocuk Hast Derg. 2019;13(6):489-91.


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