Evaluation Of Etiological Causes of Hematuria in Children

Year 2020, Volume: 14 Issue: 6, 480 - 487, 30.11.2020

Mehmet Emre Arı , Sare Gülfem Özlü , Gülay Demircin , Aysun Çaltık Yılmaz , Özlem Aydoğ , Mehmet Bülbül

https://doi.org/10.12956/tchd.597567

Abstract

Background:
Hematuria is an important and common
sign of urinary system diseases in children. Careful assessment is needed for
definitive diagnosis and appropriate management. In this study we aimed to
investigate the demographic and clinical characteristics of patients who were
admitted to our pediatric nephrology clinic with hematuria and to determine the
features that will guide the diagnosis.

Methods:
Medical charts of 370 patients who
were referred to our clinic in a period of four years with gross or microscopic
hematuria were evaluated retrospectively. Demographical data, clinical and
laboratory findings, imaging modalities and diagnosis of the patients were
investigated.

Findings: Of the patients 195 (52.7 %) were boys and 175 (47.3%) were
girls and the majority of the patients were in the age group of 6-10 years. Major
presenting feature was red colored urine (64.1 %). Non-glomerular causes were
found to be significantly higher among patients with macroscopic hematuria (p=0.002).
Acute poststreptococcal glomerulonephritis formed the majority of  glomerular hematuria and urinary system
infections formed the majority of non-glomerular hematuria causes respectively.

Conclusions: This study suggests that a careful
history, detailed physical examination and clinical evaluation may elucidate
the etiology in the majority of the patients with hematuria. Advanced imaging
modalities and renal biopsy are indicated only in selected cases.

Keywords

children, hematuria, etiology

Çocukluk Çağı Hematüri Olgularında Etiyolojik Nedenlerin İncelenmesi

Abstract

Amaç: Hematüri çocuklarda üriner sistem hastalıklarının önemli bir bulgusudur. Altta yatan ciddi hastalıkların belirtisi olabileceğinden ayırıcı tanı için dikkatli bir değerlendirme ve iyi bir klinik yaklaşım gerektirmektedir. Bu çalışmada pediatrik nefroloji kliniğimize hematüri nedeni ile başvuran hastaların demografik ve klinik özelliklerinin incelenmesi ve tanıya yol gösterecek özelliklerin belirlenmesi amaçlandı.

Hastalar ve Yöntem: Bu çalışma, kliniğimizde makroskopik ve/veya mikroskopik hematüri nedeniyle izlenmiş olan 370 hastanın dosyası retrospektif olarak değerlendirilerek gerçekleştirildi. Hastaların demografik verileri,l aboratuar sonuçları ve klinik bulguları, görüntüleme tetkikleri ve nihai tanıları araştırıldı.
Bulgular: Hastaların 195’i (%52.7) erkek,  175 (%47.7)’si kızdı ve çoğunluğu 6-10 yaş grubunda yer almaktaydı. Hastaların 234 ‘ü (%63.2) makroskopik hematüri ile başvururken , 44’ünde (%15.3) glomerüler hematüri saptandı. Makroskopik hematüri grubunda non-glomerular nedenler anlamlı olarak yüksek bulundu. Glomerüler hematüri nedenleri arasında ülkemizde halen yaygın olarak saptanan akut poststreptokokkal glomerülonefrit (APSGN), non glomerüler nedenlerden de üriner sistem enfeksiyonu en yüksek oranda görülen hastalıkları oluşturmaktaydı. 
Tartışma: Bu çalışma dikkatli bir öykü, ayrıntılı fizik muayene ve klinik değerlendirme ile hematüri ile başvuran hastaların büyük çoğunluğunda etiyolojinin aydınlatılabileceğini göstermektedir. İleri görüntüleme tetkikleri ve renal biyopsi sadece seçilmiş vakalarda endikedir.

Keywords

Çocukluk Çağı, Etiyoloji, Hematüri

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