Abstract
Iron deficiency is a common nutritional disorder worldwide and in our country, rarely associated with extreme thrombocytosis. It can also change in laboratory values such as low hemoglobin, low mean corpuscular volume (MCV). We describe here a case of extreme thrombocytosis in a healthy 4.5 year-old boy. He had reactive thrombocytosis due to iron defiency anemia. We ruled out other causes of anemia such as hemolysis, infection, absorption problems. We did not screen for malignancy due to rapid response to iron treatment.
With this case report, we wanted to focus on the relationship between iron deficiency anemia and thrombocytosis.
Keywords
References
- 1- Lanzkowsky P. Lanzkowsky’s Manual of Pediatric Hematology and Oncology, 6th Ed. San Die-go, CA: Elsevier. 2016
- 2-Dan K. Thrombocytosis in iron deficiency anemia. Internal Medicine 2005; 44(10):1025–1026.
- 3-Nathan and Oski’s Hematology and Oncology of Infancy and Childhood, 8th Ed. Philadelphia, PA: Elsevier 2015.
- 4- Kliegman R, Geme JS. Nelson textbook of pediatrics. 21st Ed. Philadelphia, PA: Elsevier; 2019
- 5- Toprak SK, Tek İ, Karakuş S, Gök N, Kurşun N. Does reactive thrombocytosis observed in iron deficiency anemia affect plasma viscosity? Turk J Hematol 2012; 29: 248-253.
- 6- De Lama Caro-Patón G, García-Salido A, Iglesias-Bouzas MI, Guillén M, Canedo-Villaroya E, Martínez-Romera I et al. Extreme reactive thrombocytosis in a healthy 6 year-old child. An Pediatr (Barc). 2014;81:318-321.
- 7- Beri S, Khan A, Hussain N, Gosalakkal J. Severe anemia causing cerebral venous sinus thrombosis in an infant. J Pediatr Neurosci. 2012;7(1):30–32.
- 8- Machen L, Abbasian J. Cerebral venous sinus thrombosis and iron deficiency anemia presenting as bilateral disc edema in a child. Can J Ophthalmol 2019;54:e108–e111
- 9- Maguire JL, deVeber G, Parkin PC. Association between iron-deficiency anemia and stroke in young children. Pediatrics 2007; 120 (5) 1053-1057.
- 10- Chang Y, Hung SH, Ling W, Lin HC, Li HC, Chung SD. Association between ischemic stroke and iron-deficiency anemia: A population-based study. PLoS One. 2017; 12(1): e0170872.
- 11- Subramaniam N, Mundkur S, Kini P, Bhaskaranand N, Aroor S. Clinicohematological Study of Thrombocytosis in Children. ISRN Hematol. 2014 Jan 29;2014:389257.
- 12-Oğuz MM, Açoglu EA. Trombositoz saptanan çocuklarda klinik ve hematolojik profilin değerlendirilmesi. Turk J Clin Lab 2019; 1: 79-84.
- 13-Sandoval C. Thrombocytosis in children with iron deficiency anemia: Series of 42 children. J Pediatr Hematol Oncol 2002;24:593.
Abstract
Dünyada ve ülkemizde sık görülen demir eksikliği anemisi hemoglobinde, ortalama eritrosit hacminde (MCV) düşüklük, trombositlerde artış gibi kan tablosunda farklı değişiklikler yapar. Nadiren trombosit düzeyinin 1.000.000/mm3’ ün üzerine çıktığı ekstrem trombositoz da gelişebilir.
Burada demir eksikliği anemisine bağlı ekstrem trombositozu olan bir olgu sunulmaktadır. Bilinen hastalığı olmayan, takipsiz, 4.5 yaşındaki erkek olgunun etiyolojisinde hemoliz, emilim kusuru, kan kaybı, enfeksiyon gibi diğer anemi nedenleri dışlanmıştır. Mevcut trombositozu ve anemisi demir tedavisine hızlıca yanıt vermiş, malignite taramasına gerek duyulmamıştır.
Bu olgu sunumu ile çocukluk çağında sık görülen trombositoz ve demir eksikliği anemisi bulgularının birlikteliğinin hatırlatılması amaçlanmıştır
Keywords
References
- 1- Lanzkowsky P. Lanzkowsky’s Manual of Pediatric Hematology and Oncology, 6th Ed. San Die-go, CA: Elsevier. 2016
- 2-Dan K. Thrombocytosis in iron deficiency anemia. Internal Medicine 2005; 44(10):1025–1026.
- 3-Nathan and Oski’s Hematology and Oncology of Infancy and Childhood, 8th Ed. Philadelphia, PA: Elsevier 2015.
- 4- Kliegman R, Geme JS. Nelson textbook of pediatrics. 21st Ed. Philadelphia, PA: Elsevier; 2019
- 5- Toprak SK, Tek İ, Karakuş S, Gök N, Kurşun N. Does reactive thrombocytosis observed in iron deficiency anemia affect plasma viscosity? Turk J Hematol 2012; 29: 248-253.
- 6- De Lama Caro-Patón G, García-Salido A, Iglesias-Bouzas MI, Guillén M, Canedo-Villaroya E, Martínez-Romera I et al. Extreme reactive thrombocytosis in a healthy 6 year-old child. An Pediatr (Barc). 2014;81:318-321.
- 7- Beri S, Khan A, Hussain N, Gosalakkal J. Severe anemia causing cerebral venous sinus thrombosis in an infant. J Pediatr Neurosci. 2012;7(1):30–32.
- 8- Machen L, Abbasian J. Cerebral venous sinus thrombosis and iron deficiency anemia presenting as bilateral disc edema in a child. Can J Ophthalmol 2019;54:e108–e111
- 9- Maguire JL, deVeber G, Parkin PC. Association between iron-deficiency anemia and stroke in young children. Pediatrics 2007; 120 (5) 1053-1057.
- 10- Chang Y, Hung SH, Ling W, Lin HC, Li HC, Chung SD. Association between ischemic stroke and iron-deficiency anemia: A population-based study. PLoS One. 2017; 12(1): e0170872.
- 11- Subramaniam N, Mundkur S, Kini P, Bhaskaranand N, Aroor S. Clinicohematological Study of Thrombocytosis in Children. ISRN Hematol. 2014 Jan 29;2014:389257.
- 12-Oğuz MM, Açoglu EA. Trombositoz saptanan çocuklarda klinik ve hematolojik profilin değerlendirilmesi. Turk J Clin Lab 2019; 1: 79-84.
- 13-Sandoval C. Thrombocytosis in children with iron deficiency anemia: Series of 42 children. J Pediatr Hematol Oncol 2002;24:593.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | CASE REPORTS |
| Authors | |
| Publication Date | May 25, 2021 |
| Submission Date | May 13, 2020 |
| Published in Issue | Year 2021 Volume: 15 Issue: 3 |
The publication language of Turkish Journal of Pediatric Disease is English.
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