Abstract
Iron deficiency is a common nutritional disorder worldwide and in our country, rarely associated with extreme thrombocytosis. It can also change in laboratory values such as low hemoglobin, low mean corpuscular volume (MCV). We describe here a case of extreme thrombocytosis in a healthy 4.5 year-old boy. He had reactive thrombocytosis due to iron defiency anemia. We ruled out other causes of anemia such as hemolysis, infection, absorption problems. We did not screen for malignancy due to rapid response to iron treatment.
With this case report, we wanted to focus on the relationship between iron deficiency anemia and thrombocytosis.
Keywords
References
- 1- Lanzkowsky P. Lanzkowsky’s Manual of Pediatric Hematology and Oncology, 6th Ed. San Die-go, CA: Elsevier. 2016
- 2-Dan K. Thrombocytosis in iron deficiency anemia. Internal Medicine 2005; 44(10):1025–1026.
- 3-Nathan and Oski’s Hematology and Oncology of Infancy and Childhood, 8th Ed. Philadelphia, PA: Elsevier 2015.
- 4- Kliegman R, Geme JS. Nelson textbook of pediatrics. 21st Ed. Philadelphia, PA: Elsevier; 2019
- 5- Toprak SK, Tek İ, Karakuş S, Gök N, Kurşun N. Does reactive thrombocytosis observed in iron deficiency anemia affect plasma viscosity? Turk J Hematol 2012; 29: 248-253.
- 6- De Lama Caro-Patón G, García-Salido A, Iglesias-Bouzas MI, Guillén M, Canedo-Villaroya E, Martínez-Romera I et al. Extreme reactive thrombocytosis in a healthy 6 year-old child. An Pediatr (Barc). 2014;81:318-321.
- 7- Beri S, Khan A, Hussain N, Gosalakkal J. Severe anemia causing cerebral venous sinus thrombosis in an infant. J Pediatr Neurosci. 2012;7(1):30–32.
- 8- Machen L, Abbasian J. Cerebral venous sinus thrombosis and iron deficiency anemia presenting as bilateral disc edema in a child. Can J Ophthalmol 2019;54:e108–e111
- 9- Maguire JL, deVeber G, Parkin PC. Association between iron-deficiency anemia and stroke in young children. Pediatrics 2007; 120 (5) 1053-1057.
- 10- Chang Y, Hung SH, Ling W, Lin HC, Li HC, Chung SD. Association between ischemic stroke and iron-deficiency anemia: A population-based study. PLoS One. 2017; 12(1): e0170872.
- 11- Subramaniam N, Mundkur S, Kini P, Bhaskaranand N, Aroor S. Clinicohematological Study of Thrombocytosis in Children. ISRN Hematol. 2014 Jan 29;2014:389257.
- 12-Oğuz MM, Açoglu EA. Trombositoz saptanan çocuklarda klinik ve hematolojik profilin değerlendirilmesi. Turk J Clin Lab 2019; 1: 79-84.
- 13-Sandoval C. Thrombocytosis in children with iron deficiency anemia: Series of 42 children. J Pediatr Hematol Oncol 2002;24:593.
Abstract
Dünyada ve ülkemizde sık görülen demir eksikliği anemisi hemoglobinde, ortalama eritrosit hacminde (MCV) düşüklük, trombositlerde artış gibi kan tablosunda farklı değişiklikler yapar. Nadiren trombosit düzeyinin 1.000.000/mm3’ ün üzerine çıktığı ekstrem trombositoz da gelişebilir.
Burada demir eksikliği anemisine bağlı ekstrem trombositozu olan bir olgu sunulmaktadır. Bilinen hastalığı olmayan, takipsiz, 4.5 yaşındaki erkek olgunun etiyolojisinde hemoliz, emilim kusuru, kan kaybı, enfeksiyon gibi diğer anemi nedenleri dışlanmıştır. Mevcut trombositozu ve anemisi demir tedavisine hızlıca yanıt vermiş, malignite taramasına gerek duyulmamıştır.
Bu olgu sunumu ile çocukluk çağında sık görülen trombositoz ve demir eksikliği anemisi bulgularının birlikteliğinin hatırlatılması amaçlanmıştır
Keywords
References
- 1- Lanzkowsky P. Lanzkowsky’s Manual of Pediatric Hematology and Oncology, 6th Ed. San Die-go, CA: Elsevier. 2016
- 2-Dan K. Thrombocytosis in iron deficiency anemia. Internal Medicine 2005; 44(10):1025–1026.
- 3-Nathan and Oski’s Hematology and Oncology of Infancy and Childhood, 8th Ed. Philadelphia, PA: Elsevier 2015.
- 4- Kliegman R, Geme JS. Nelson textbook of pediatrics. 21st Ed. Philadelphia, PA: Elsevier; 2019
- 5- Toprak SK, Tek İ, Karakuş S, Gök N, Kurşun N. Does reactive thrombocytosis observed in iron deficiency anemia affect plasma viscosity? Turk J Hematol 2012; 29: 248-253.
- 6- De Lama Caro-Patón G, García-Salido A, Iglesias-Bouzas MI, Guillén M, Canedo-Villaroya E, Martínez-Romera I et al. Extreme reactive thrombocytosis in a healthy 6 year-old child. An Pediatr (Barc). 2014;81:318-321.
- 7- Beri S, Khan A, Hussain N, Gosalakkal J. Severe anemia causing cerebral venous sinus thrombosis in an infant. J Pediatr Neurosci. 2012;7(1):30–32.
- 8- Machen L, Abbasian J. Cerebral venous sinus thrombosis and iron deficiency anemia presenting as bilateral disc edema in a child. Can J Ophthalmol 2019;54:e108–e111
- 9- Maguire JL, deVeber G, Parkin PC. Association between iron-deficiency anemia and stroke in young children. Pediatrics 2007; 120 (5) 1053-1057.
- 10- Chang Y, Hung SH, Ling W, Lin HC, Li HC, Chung SD. Association between ischemic stroke and iron-deficiency anemia: A population-based study. PLoS One. 2017; 12(1): e0170872.
- 11- Subramaniam N, Mundkur S, Kini P, Bhaskaranand N, Aroor S. Clinicohematological Study of Thrombocytosis in Children. ISRN Hematol. 2014 Jan 29;2014:389257.
- 12-Oğuz MM, Açoglu EA. Trombositoz saptanan çocuklarda klinik ve hematolojik profilin değerlendirilmesi. Turk J Clin Lab 2019; 1: 79-84.
- 13-Sandoval C. Thrombocytosis in children with iron deficiency anemia: Series of 42 children. J Pediatr Hematol Oncol 2002;24:593.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Internal Diseases |
| Journal Section | CASE REPORTS |
| Authors | |
| Publication Date | May 25, 2021 |
| Submission Date | May 13, 2020 |
| Published in Issue | Year 2021 Volume: 15 Issue: 3 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.