Objective: The index of cardio-electrophysiological balance (iCEB) is a new non-invasive marker that can be used to predict malignant ventricular arrhythmias. Pediatric studies on iCEB are limited in number. Our study aimed to determine the range of its values in different age groups among school-age children.
Material and Methods: The study included patients aged 5-17 admitted to Gülhane Training and Research Hospital Pediatric Cardiology Outpatient Clinic between March 2020 and March 2022 without a history of chronic disease, cardiac disease, arrhythmia, or cardiac surgery. Participants were categorised into ages 5-8, 9-12, and 13-17. The iCEB and iCEBc values were calculated and compared between groups.
Results: The total number of 1303 cases were categorised into the 5-8 (n=270), 9-12 (n=389), and 13-17 (n=644) age groups. The mean iCEB and iCEBc values for all age groups were 4.39±0.53 and 5.16±0.53, respectively. Any difference was not detected among age groups of 5-8, 9-12, and 13-17 years in terms of iCEB and iCEBc values (4.42±0.56, 4.39±0.53 and 4.39±0.52 vs. 5.19±0.56, 5.15±0.55 and 5.16±0.52, respectively). However, a significant difference was found between male (n=699) and female (n=604) patients in terms of mean iCEB (4.23±0.52 vs. 4.59±0.47) and iCEBc (4.98±0.53 vs. 5.38±0.46) values (p <0.001).
Conclusion: iCEB and iCEBc values in school-age children did not differ according to age groups. However, these values differed between boys and girls. This study is the first to reveal normal ranges of iCEB and iCEBc values in school-age children.
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Amaç: Kardiyo-elektrofizyolojik denge indeksi (iCEB), malign ventriküler aritmileri tahmin etmede kullanılabilecek yeni, invazif olmayan bir belirteçtir. iCEB ile ilgili pediatrik çalışmalar sayıca sınırlıdır. Çalışmamız okul çağındaki çocuklarda farklı yaş gruplarındaki iCEB değerlerinin aralığını belirlemeyi amaçladı.
Gereç ve Yöntemler: Gülhane Eğitim ve Araştırma Hastanesi Çocuk Kardiyoloji Polikliniğine Mart 2020-Mart 2022 tarihleri arasında başvuran, kronik hastalık, kalp hastalığı, aritmi ve kalp cerrahisi öyküsü olmayan 5-17 yaş arası hastalar çalışmaya dahil edildi. Katılımcılar 5-8, 9-12 ve 13-17 yaş gruplarına ayrıldı. iCEB ve iCEBc değerleri hesaplandı ve gruplar arasında karşılaştırıldı.
Bulgular: Toplam 1303 vaka 5-8 (n=270), 9-12 (n=389) ve 13-17 (n=644) yaş gruplarına ayrıldı. Tüm yaş grupları için ortalama iCEB ve iCEBc değerleri sırasıyla 4.39±0.53 ve 5.16±0.53’di. iCEB ve iCEBc değerleri açısından 5-8, 9-12 ve 13-17 yaş grupları arasında farklılık saptanmadı (4.42±0.56, 4,.39±0.53 ve 4.39±0.52 vs. 5.19±0.56, 5.15±0.55 ve 5.16±0.52). Ancak erkek (n=699) ve kadın (n=604) hastalar arasında ortalama iCEB (4.23±0.52 vs. 4.59±0.47) ve iCEBc (4.98±0.53 vs. 5.38±0.46) değerleri açısından anlamlı fark bulundu (p <0.001).
Sonuç: Okul çağındaki çocuklarda iCEB ve iCEBc değerleri yaş gruplarına göre farklılık göstermedi. Ancak bu değerler kız ve erkek çocuklar arasında farklılık göstermektedir. Bu çalışma, okul çağındaki çocuklarda iCEB ve iCEBc değerlerinin normal aralıklarını ortaya koyan ilk çalışmadır.
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Primary Language | English |
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Subjects | Clinical Sciences (Other) |
Journal Section | ORIGINAL ARTICLES |
Authors | |
Project Number | - |
Early Pub Date | June 10, 2024 |
Publication Date | November 18, 2024 |
Submission Date | March 15, 2024 |
Acceptance Date | May 7, 2024 |
Published in Issue | Year 2024 Volume: 18 Issue: 6 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 6 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
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