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Çocukluk Çağında Alerjik Hastalıklarda Uyku Bozukluklarının Değerlendirilmesi

Year 2024, Volume: 18 Issue: 6, 342 - 347, 18.11.2024
https://doi.org/10.12956/tchd.1471192

Abstract

Amaç: Uyku, fiziksel ve ruhsal sağlıkta ve refahta birçok kritik rol oynayan insan yaşamının hayati bir bileşenidir. Literatürde alerjik hastalık tanısı alan çocuklarla, özellikle de okul öncesi çağdaki çocuklarla ilgili çok az çalışma sunulmuştur. Çalışmamızın amacı alerjik hastalığı olan çocuklarda uykku bozukluklarının değerlendirilmesiydi.

Gereç ve Yöntemler: Bu retrospektif çalışma, 1 Ocak-20 Mart tarihleri arasında Hastanemiz Çocuk İmmunoloji ve Alerji Polikliniği’nde alerjik rinit, astım ve/veya atopik dermatit tanısı konulan hastalar arasında gerçekleştirildi. Poliklinik ziyareti sırasında araştırmacı tarafından ebeveynlere ‘ Çocuklar için Uyku Bozuklukları Ölçeği (SDSC) uygulanmıştır.

Bulgular: Bu çalışmaya 145 hasta dahil edildi. Beş (%3.4) hastada klinik olarak anlamlı SDSC skoru saptandı. Alerjik hastalık semptomu olan ve olmayan hastaların uyku bozukluğu ölçeği toplam puan ortalamaları arasında istatistiksel olarak anlamlı farklılık olduğu saptandı. Alerjik hastalık belirtileri olan hastalar arasında SDSC (değişmeyecek) toplam puan ortalaması ile burun tıkanıklığı, öksürük ve aktivite kısıtlılığı olan hastalar arasında istatistiksel olarak anlamlı fark olduğu saptandı. Oral antihistaminik tedavi kullanan hastaların ortalama skorları daha yüksek olma eğilimindeydi.

Sonuç: Bu çalışmada 145 hastanın 5’inde (%3.4) klinik olarak anlamlı SDSC (değişmeyecek) skoru saptandı. Alerjik hastalık belirtileri olan hastaların çocuk uyku bozukluğu ölçeği ortalama puanın daha yüksek olduğu görüldü. Burun tıkanıklığı, öksürük ve hareket kısıtlılığı olan hastaların ortalama SDSC (değişmeyecek) puanı daha yüksek olma eğilimindeydi.

References

  • Consensus Conference Panel; Watson NF, Badr MS, Belenky G, Bliwise DL, Buxton OM, et al. Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the recommended amount of sleep for a healthy adult: methodology and discussion. Sleep 2015;38:1161–83.
  • Banks S, Dinges DF. Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med 2007;3:519–28.
  • Buyyse DJ. Sleep health: can we define it? Does it matter? Sleep 2014;37:9-17.
  • Bathory E, Tomopoulos S. Sleep regulation, Physiology and Development, Sleep duration and patterns, sleep hygiene in infants, toddlers, and preschool-age children. Curr Probl Pediatr Adolesc Health Care 2017;47:29-42.
  • Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch 2012;463:121-37.
  • Thabet F, Tabarki B. Common sleep disorders in children: assessment and treatment. Neurosciences (Riyadh) 2023;28:85-90.
  • Owens J. Classification and epidemiology of childhood sleep disorders. Prim Care 2008;35:533–46.
  • Carter KA, Hathaway NE, Lettieri CF. Common sleep disorders in children. Am Fam Physician 2014;89:368-77.
  • Valero A, Quirce S, Dávila I, Delgado J, Domínguez-Ortega J. Allergic respiratory disease: Different allergens, different symptoms. Allergy 2017;72:1306–16.
  • Lamnisos D, Moustaki M, Kolokotroni O, Koksoy H, Faiz M, Arifoğlu K, et al. Prevalence of asthma and allergies in children from the Greek-Cypriot and Turkish-Cypriot communities in Cyprus: a bi- communal cross-sectional study. BMC Public Health 2013:13:585.
  • Koinis-Mitchell D, Craig T, Esteban CA, Klein RB. Sleep and allergic disease: A summary of the literature and future directions for research. J Allergy Clin Immunol 2012;130:1275-81.
  • Tamm S, Cervenka S, Forsberg A, Estelius J, Grunewald J, Gyllfors P, et al. Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: a [11C]PBR28 PET study. Brain Behav Immun 2018;68:146–57.
  • Ma Y, Tang J, Wen Y, Hu Y, Liang J, Jiang L, et al. Associations of sleep problems with asthma and allergic rhinitis among Chinese preschoolers. Sci Rep 2022;12:8102.
  • Wang X, Gao X, Yang W, Wang X, Li S, Jiang F, et al. Sleep disorders and allergic diseases in Chinese toddlers. Sleep Med 2017; 37:174–9.
  • Romeo DM, Bruni O, Brogna C, et al. Application of the sleep disturbance scale for children (SDSC) in preschool age. Eur J Paediatr Neurol 2013;17:374-82.
  • Bousquet J, Schünemann HJ, Togias A, et al. Next-generation Allergic Rhinitis and Its impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assesment, Development and Evaluation (GRADE) and real-world evidence. J Allergy Clin Immunol 2020;145:70-80.e3.
  • Kanwar AJ, Dhar S, Kaur S. Evaluation of minor clinical features of atopic dermatitis. Pediatr Dermatol 1991;8 :114-6.
  • Bruni O, Ottaviano S, Guidetti V, Romoli M, Innocenzi M, Cortesi F, et al. The sleep disturbance scale for children (SDSC) construction and validation of an instrument to evaluate sleep disturbances in childhood and adolescence. J Sleep Res 1996;5:251-61.
  • Ağadayı E, Çelik N, Ayhan Başer D. Turkish Validity and Reliability of the Sleep Disturbance Scale for Children. J Turk Sleep Med 2020;2:65-72.
  • Romeo DM, Cordaro G, Macchione E, Venezia I, Brogna C, Mercunri E, et al. Application of the sleep disturbance scalefor children (SDSC) in infants and toddlers (6-36 months). Sleep Med 2021;81:62-8.
  • Sherrey J, Biggs S, Dorrian J, Martin J, Gold M, Kennedy D, et al. Allergic disease, sleep problems, and psychological distress in children recruited from the general community. Ann Allergy Asthma Immunol 2022;129:366-72.
  • Koinis-Mitchell D, Kopel SJ, Boergers J, Ramos K, LeBourgeois M, McQuaid EL, et al. Asthma, Allergic rhinitis, and sleep problems in urban children. J Clin Sleep Med 2015;11:101-10.
  • Liu X, Hong C, Liu Z, Fan L, Yin M, Chen Y, et al. Association of sleep disorders with asthma: a meta-analysis. BMJ Open Respir Res 2023;10:e001661.
  • Chugh IM, Khanna P, Shah A. Nocturnal symptoms and sleep disturbances in clinically stable asthmatic children. Asian Pac J Allergy Immunol 2006;24:135-42.
  • Furtado PR, Maciel ACC, Barbosa RRT, Silva AAM, Freitas DA, et al. Association between quality of life, severity of asthma, sleep disorders and exercise capacity in children with asthma: across-sectional study. Braz J Phys Ther 2019;23:12-8.
  • Loekmanwidjaja J, Carneiro ACF, Nishinaka MLC, Munhoes DA, Benezoli G, Wandalsen GF, et al. Sleep disorders in children with moderate to severe persistent allergic rhinitis. Braz J Otorhinolaryngol 2018;84:178-84.
  • Bawany F, Northcott CA, Beck LA, Pigeon WR. Sleep disturbances and atopicdermatitis: Relationships, methods for assessment, and therapies. J Allergy Clin Immunol Pract 2021;9:1488-500.
  • Ramirez FD, Chen S, Langan SM, Prather AA, McCulloch CE, Kidd SA, et al. Association of atopic dermatitis with sleep quality in children. JAMA Pediatr 2019;173:e190025.

Evaluation of Sleep Disorders in Allergic Diseases in Childhood

Year 2024, Volume: 18 Issue: 6, 342 - 347, 18.11.2024
https://doi.org/10.12956/tchd.1471192

Abstract

Objective: Sleep is a vital component of human life that serves many critical roles in physical and mental health, and well-being. There were few studies on children, diagnosed with allergic diseases, especially preschool children. The aim of our study mas to evaluate sleep disorders in children with allergic diseases.

Material and Methods: This retrospective study was conducted in Dr. Burhan Nalbantoğlu Hospital Child Immunology and Allergy outpatient clinic between January 1 and March 20, 2024, patients included who were diagnosed with allergic rhinitis, asthma and/or atopic dermatitis.The ‘Sleep Disturbance Scale for children (SDSC) was applied to the parents by the researcher during the outpatient clinic visit.

Results: In this study, 145 patients were involved. Five (3.4%) patients had clinically significant SDSC score. There was a statistically significant difference in the Children’s Sleep Disturbance Scale mean score between having and not having symptoms of allergic diseases. Patients diagnosed wheezy child tended to have higher mean score of SHY. Among patients having symptoms of allergic diseases, there was statistically significant difference in the SDSC mean score between having nose congestion, cough, and activity limitation and not having these symptoms. Patients using oral antihistaminic treatment tended to have higher total mean scores of SDSC.

Conclusion: In this study, out of 145 patients, 5 (3.4%) patients had clinically significant SDSC score. Patients having symptom of allergic diseases tended to have higher total mean score of childrens’ sleep disturbance scale. Patients diagnosed wheezy child tended to have higher mean score of SHY. Patients having nose congestion, cough, and activity limitation tended to have higher total mean score of SDSC.

References

  • Consensus Conference Panel; Watson NF, Badr MS, Belenky G, Bliwise DL, Buxton OM, et al. Joint Consensus Statement of the American Academy of Sleep Medicine and Sleep Research Society on the recommended amount of sleep for a healthy adult: methodology and discussion. Sleep 2015;38:1161–83.
  • Banks S, Dinges DF. Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med 2007;3:519–28.
  • Buyyse DJ. Sleep health: can we define it? Does it matter? Sleep 2014;37:9-17.
  • Bathory E, Tomopoulos S. Sleep regulation, Physiology and Development, Sleep duration and patterns, sleep hygiene in infants, toddlers, and preschool-age children. Curr Probl Pediatr Adolesc Health Care 2017;47:29-42.
  • Besedovsky L, Lange T, Born J. Sleep and immune function. Pflugers Arch 2012;463:121-37.
  • Thabet F, Tabarki B. Common sleep disorders in children: assessment and treatment. Neurosciences (Riyadh) 2023;28:85-90.
  • Owens J. Classification and epidemiology of childhood sleep disorders. Prim Care 2008;35:533–46.
  • Carter KA, Hathaway NE, Lettieri CF. Common sleep disorders in children. Am Fam Physician 2014;89:368-77.
  • Valero A, Quirce S, Dávila I, Delgado J, Domínguez-Ortega J. Allergic respiratory disease: Different allergens, different symptoms. Allergy 2017;72:1306–16.
  • Lamnisos D, Moustaki M, Kolokotroni O, Koksoy H, Faiz M, Arifoğlu K, et al. Prevalence of asthma and allergies in children from the Greek-Cypriot and Turkish-Cypriot communities in Cyprus: a bi- communal cross-sectional study. BMC Public Health 2013:13:585.
  • Koinis-Mitchell D, Craig T, Esteban CA, Klein RB. Sleep and allergic disease: A summary of the literature and future directions for research. J Allergy Clin Immunol 2012;130:1275-81.
  • Tamm S, Cervenka S, Forsberg A, Estelius J, Grunewald J, Gyllfors P, et al. Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: a [11C]PBR28 PET study. Brain Behav Immun 2018;68:146–57.
  • Ma Y, Tang J, Wen Y, Hu Y, Liang J, Jiang L, et al. Associations of sleep problems with asthma and allergic rhinitis among Chinese preschoolers. Sci Rep 2022;12:8102.
  • Wang X, Gao X, Yang W, Wang X, Li S, Jiang F, et al. Sleep disorders and allergic diseases in Chinese toddlers. Sleep Med 2017; 37:174–9.
  • Romeo DM, Bruni O, Brogna C, et al. Application of the sleep disturbance scale for children (SDSC) in preschool age. Eur J Paediatr Neurol 2013;17:374-82.
  • Bousquet J, Schünemann HJ, Togias A, et al. Next-generation Allergic Rhinitis and Its impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assesment, Development and Evaluation (GRADE) and real-world evidence. J Allergy Clin Immunol 2020;145:70-80.e3.
  • Kanwar AJ, Dhar S, Kaur S. Evaluation of minor clinical features of atopic dermatitis. Pediatr Dermatol 1991;8 :114-6.
  • Bruni O, Ottaviano S, Guidetti V, Romoli M, Innocenzi M, Cortesi F, et al. The sleep disturbance scale for children (SDSC) construction and validation of an instrument to evaluate sleep disturbances in childhood and adolescence. J Sleep Res 1996;5:251-61.
  • Ağadayı E, Çelik N, Ayhan Başer D. Turkish Validity and Reliability of the Sleep Disturbance Scale for Children. J Turk Sleep Med 2020;2:65-72.
  • Romeo DM, Cordaro G, Macchione E, Venezia I, Brogna C, Mercunri E, et al. Application of the sleep disturbance scalefor children (SDSC) in infants and toddlers (6-36 months). Sleep Med 2021;81:62-8.
  • Sherrey J, Biggs S, Dorrian J, Martin J, Gold M, Kennedy D, et al. Allergic disease, sleep problems, and psychological distress in children recruited from the general community. Ann Allergy Asthma Immunol 2022;129:366-72.
  • Koinis-Mitchell D, Kopel SJ, Boergers J, Ramos K, LeBourgeois M, McQuaid EL, et al. Asthma, Allergic rhinitis, and sleep problems in urban children. J Clin Sleep Med 2015;11:101-10.
  • Liu X, Hong C, Liu Z, Fan L, Yin M, Chen Y, et al. Association of sleep disorders with asthma: a meta-analysis. BMJ Open Respir Res 2023;10:e001661.
  • Chugh IM, Khanna P, Shah A. Nocturnal symptoms and sleep disturbances in clinically stable asthmatic children. Asian Pac J Allergy Immunol 2006;24:135-42.
  • Furtado PR, Maciel ACC, Barbosa RRT, Silva AAM, Freitas DA, et al. Association between quality of life, severity of asthma, sleep disorders and exercise capacity in children with asthma: across-sectional study. Braz J Phys Ther 2019;23:12-8.
  • Loekmanwidjaja J, Carneiro ACF, Nishinaka MLC, Munhoes DA, Benezoli G, Wandalsen GF, et al. Sleep disorders in children with moderate to severe persistent allergic rhinitis. Braz J Otorhinolaryngol 2018;84:178-84.
  • Bawany F, Northcott CA, Beck LA, Pigeon WR. Sleep disturbances and atopicdermatitis: Relationships, methods for assessment, and therapies. J Allergy Clin Immunol Pract 2021;9:1488-500.
  • Ramirez FD, Chen S, Langan SM, Prather AA, McCulloch CE, Kidd SA, et al. Association of atopic dermatitis with sleep quality in children. JAMA Pediatr 2019;173:e190025.
There are 28 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section ORIGINAL ARTICLES
Authors

Azize Pınar Metbulut 0000-0001-8823-5960

Early Pub Date July 30, 2024
Publication Date November 18, 2024
Submission Date April 19, 2024
Acceptance Date June 4, 2024
Published in Issue Year 2024 Volume: 18 Issue: 6

Cite

Vancouver Metbulut AP. Evaluation of Sleep Disorders in Allergic Diseases in Childhood. Türkiye Çocuk Hast Derg. 2024;18(6):342-7.


The publication language of Turkish Journal of Pediatric Disease is English.


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