Trace Element Analysis of Some Medicinal and Aromatic Plant Species by ICP-MS

Year 2023, , 21 - 29, 27.03.2023

Ebubekir İzol , İsa Çiçek , Lütfi Behçet , Enes Kaya , Abbas Tarhan

https://doi.org/10.46810/tdfd.1113610

Cited By: 4

Abstract

In this study, analysis of trace elements (Al, V, Cr, Ni, Cu, Zn, As, Ag, Cd, Sn, Hg, Pb) of taxa, such as Alkanna trichophila Hub.-Mor. var. trichophila, Anchusa azurea Mill. var. azurea ( Boraginaceae ), Achillea biebersteinii Afan., Centaurea iberica Trev. ex Sprengel (Asteraceae), Ajuga vestita Boiss.(Endemic), Teucrium polium L. ( Lamiaceae ) by ICP-MS technique, collected in Çermik district of Turkey's Diyarbakır province and used for folk or medicinal purposes, was conducted quantitatively and qualitatively using the ICP-MS technique. As a result of the analysis, Sn, Hg, Pb elements in all six plant taxa could not be determined since they were below the lod value. It is essential for consumers that these three toxic elements are not specified in plant species. The highest concentration was determined in element Al (26.04-193.5 mg/kg). With this study, some metal characterisations and concentrations of medicinal plants were determined.

Keywords

ICP-MS, Çermik, trace element analysis, plants, minerals

References

• [1] Essawi, T., and M. Srour. “Screening of Some Palestinian Medicinal Plants for Antibacterial Activity.” Journal of Ethnopharmacology. 2000; 70 (3): 343–349. doi:10.1016/S0378-8741(99)00187-7.
• [2] WHO Expert Committee on Biological Standardization. WHO Technical Report Series 927. Fifty-Fourth Report. Annex1 WHO Guidelines on Nonclinical Evaluation of Vaccines; 2005.
• [3] Özbek, Z. Investigation of the Applicability of Limit Values for Heavy Metals in Soil. Master Thesis, 9(1): 76–99; 2010.
• [4] Yener, İ. “Trace Element Analysis in Some Plants Species by Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES).” 2019; doi:10.21597/jist.
• [5] Alloway, Brian J. “Heavy Metals and Metalloids as Micronutrients for Plants and Animals.” In. 2013; 195–209. Springer, Dordrecht. doi:10.1007/978-94-007-4470-7_7.
• [6] İzol, E., H. Temel, M.A. Yilmaz, I. Yener, O.T. Olmez, E. Kaplaner, et al. A Detailed Chemical and Biological Investigation of Twelve Allium Species from Eastern Anatolia with Chemometric Studies. Chemistry & Biodiversity. 2021; 18, no. 1 (January 8): e2000560. doi:10.1002/cbdv.202000560.
• [7] İzol, E. and İnik, O. Current Analysis Methods of Heavy Metals in Soil. European Journal of Science and Technology. 2022; (36), 116-120. Doi: 10.31590/ejosat.1111496.
• [8] Önder, S. Investigation of Heavy Metal Pollution in Agricultural Fields Irrigated with Wastewater. Master Thesis, 66; 2012.
• [9] Baba, B. Quantitative Determination of Arsenic (As) in Hot Springs of Biga Peninsula (Çanakkale) by Voltammetry and Inductively Coupled Plasma-Mass Spectrometer (Icp-Ms) Techniques. Master Thesis; 2007.
• [10] Çiçek, İ. Ethnobotanical Characteristics of Çermik District and Its Villages (Diyarbakır). Bingol University Institute of Science and Technology, Master Thesis; 2019.
• [11] Özturk, M., and H. Özcelik. Useful plants of Eastern Anatolia. Semih Offset Printing Facilities, Ankara; 1991.
• [12] Özçelik, H., G. Ay, and M.Öztürk. Some economically important plants of Eastern and Southeastern Anatolia. X. National Biology Congress, Proceedings, 18–20 July, Erzurum; 1990. p. 1-10.
• [13] Gümüş, İ. Local names and uses of some useful plants growing in Ağrı region. Turkish Journal of Botany, 18: 107-112; 1994. [14] Işık, S., A. Gonuz, Ü. Arslan, and M. Ozturk. Ethnobotanical Characteristics of Some Species in Afyon (Turkey). Journal of Herb Systematic Botany. 1995; 2 (1): 161-166.
• [15] Honda G, E. Yeşilada, M. Tabata, E. Sezik, T. Fujita, Y. Takeda, et al. Traditionalmedicine in Turkey VI. folk medicinei in west Anatolia: Afyon, Kütahya, Denizli, Muğla, Aydın provinces. Journal of Ethnopharmacology. 1996; 53: 75-87.
• [16] Yeşilada, E., G. Honda, E. Sezik, M. Tabata, T. Fujita, T. Tanaka, et al. Traditional Medicine in Turkey. V. Folk Medicine in the Inner Taurus Mountains. Journal of Ethnopharmacology. 1995; 46, no. 3 (June 5): 133–152.doi:10.1016/0378-8741(95)01241-5.
• [17] Çakılcıoğlu, U. Türkoğlu and İ. M. Kursat. Ethnobotanical features of Harput (Elazig) and its surroundings. Eastern Anatolia Region Studies (Daum) Journal. 2007; 5(2): 22-28 .
• [18] Yapıcı, İ.Ü., H. Hoşgören, and Ö. Saya. Ethnobotanical Features of Kurtalan (Siirt) District. Journal of Dicle University Ziya Gökalp Faculty of Education. 2009; Vol. 12.
• [19] Deniz, L., A. Serteser, and M. Kargioglu. Local Names and Ethnobotanical Characteristics of Some Plants in Uşak University and Its Neighborhood. AKU Journal of Science and Technology. 2010; 10, no. 01: 57–72.
• [20] Melikoğlu, G., S. Kurtoğlu, and Ş. Culture.. Herbs Traditionally Used in Asthma Treatment in Turkey. Marmara Pharmaceutical Journal. 2015; 19, no. 1: 1–11.
• [21] Altundağ E. Public Use of Natural Plants of Iğdır Province (Eastern Anatolia Region). Istanbul University Institute of Health Sciences, PhD Thesis; 2009.
• [22] Güldaş, N. Determination of Usage Areas of Some Plants with Ethnobotanical Value in Adiyaman Province. Fırat University, Institute of Science and Technology. Master's Thesis; 2009.
• [23] Tetik, F. A Research on Plants with Ethnobotanical Value of Malatya Province. Fırat University Institute of Science and Technology, Master Thesis; 2011.
• [24] Polat, R., S. Selvi, U. Çakılcıoğlu, and M. Açar. Ethnobotanical investigation of wild plants sold in Bingöl neighborhood markets. Biological Diversity and Conservation. 2012; 5(3): 155-161.
• [25] Yiğit SŞ. Plants Sold in Gaziantep Province Herbalists and Ethnobotanical Characteristics. Gaziantep University Department of Biology, Master's Thesis; 2014.
• [26] Doğan, A. Ethnobotanical researches in Pertek (Tunceli) region. M.U. Institute of Health Sciences, Ph.D. Thesis; 2014.
• [27] Tonbul,S., and Y. Altan. Some plants used by the people for various purposes in the Elazig region. Fırat University Journal (Social Sciences). 1989; 3(2): 267-278.
• [28] Ayanoğlu, F., A. Mert, D.A. Kaya. Detection and Collection of Some Important Medicinal and Fragrant Plants Used by the People in the Hatay Region. Mustafa Kemal University, Journal of the Faculty of Agriculture. 1999; 4(1-2): 101-116.
• [29] Özçelik, H. and C. Balabanlı.. Medicinal and aromatic plants of Burdur province. I. Burdur Symposium, Burdur; 2005. p. 1127-1136
• [30] Çakılcıoğlu, U. Türkoğlu and İ. M. Kursat. Ethnobotanical features of Harput (Elazig) and its surroundings. Eastern Anatolia Region Studies (Daum) Journal. 2007; 5(2): 22-28 .
• [31] Çimen, O.D. Ethnobotanical studies on folk remedies used in Konya. Gazi University Institute of Health Sciences, Master's thesis; 2007.
• [32] Yeşil, Y. An ethnobotanical research in Kürecik (Akçadağ/Malatya) subdivision. Istanbul University Institute of Health Sciences, Master Thesis, p. 275; 2007.
• [33] Doğan G., and E. Bağcı. Plants used by the people in some settlements of Elazığ based on their traditional ecological knowledge and their ethnobotanical features. Firat Univ. Journal of Science. 2011; 23(2): 77-86
• [34] Kaval, İ. Ethnobotanical Characteristics of Geçitli (Hakkari) and Its Surroundings Yüzüncü Yıl University, Institute of Science and Technology, Master Thesis, p. 279; 2011.
• [35] Mükemre, M. Ethnobotanical Characteristics of Konalga, Sırmalı, Dokuzdam Villages (Çatak-Van) and Their Surroundings. Yüzüncü Yıl University Graduate School of Natural and Applied Sciences, Department of Biology, Master's Thesis, 53(9): 1689–1699; 2013.
• [36] Yazıcıoğlu, A., and E.Tuzlacı. Folk medicinal plants of Trabzon (Turkey). Fitoterapia, 67(4): 307-318; 1996.
• [37] Baytop, T. Herbal Treatment in Turkey; Past And Today. Nobel Medical Bookstores Ltd. Sti, p. 480 Istanbul; 1999.
• [38] Tuzlacı, E. For Healing - herbal folk remedies of Turkey. Alfa Publications, Istanbul; 2006.
• [39] Kıran, Ö. Medicinal plants in the flora of Kozan region and their use in folk medicine. Department of Deontology and History of Medicine Çukurova University Institute of Health Sciences, M.Sc., p. 66; 2006.
• [40] İzol, E., E. Kaya, and D. Karahan. Investigation of Some Metals in Honey Samples Produced in Different Regions of Bingöl Province by ICP-MS. Mellifera. 2021; 21, no. 1: 1–17.
• [41] Osw, P.S., and F.H.S. Hussain. EAJSE Inductively Coupled Plasma-Optical Emission Spectrometric Determination of Some Elements from Anchusa Azurea Mill . Collected in Iraqi Kurdistan Region. 2020; 6, no. 2: 21–30.
• [42] Dissanayake, C. B., and R. Chandrajith. “Sri Lanka-Madagascar Gondwana Linkage: Evidence for a Pan-African Mineral Belt.” Journal of Geology. 1999;107 (2): 223–235.
• [43] Cherian, M.G., and M. Nordberg. Cellular Adaptation in Metal Toxicology and Metallothionein. Toxicology. 1983; 28, no. 1–2 (September 1): 1–15. Elsevier: 1–15. doi:10.1016/0300-483X(83)90101-4.
• [44] Evangelou, Angelos M. “Vanadium in Cancer Treatment.” Critical Reviews in Oncology/Hematology. 2002;42 (3): 249–265. doi:10.1016/S1040-8428(01)00221-9.
• [45] Potortì, A.G., V. Lo Turco, and G. Di Bella. Chemometric Analysis of Elements Content in Algerian Spices and Aromatic Herbs. 2021; LWT 138 (March): 110643. doi:10.1016/j.lwt.2020.110643.
• [46] WHO. World Health Organization guidelines for assessing quality of herbal medicines with reference to contaminants and residues. Department of Technical Cooperation for Essential Drugs and Traditional Medicine. Geneva: World Health Organization; 2007.
• [47] Pereira, João B., and Kelly G.F. Dantas. “Evaluation of Inorganic Elements in Cat’s Claw Teas Using ICP OES and GF AAS.” Food Chemistry. 2016; 196 (April). Elsevier Ltd: 331–337. doi:10.1016/j.foodchem.2015.09.057.
• [48] Ebdon L., L. Pitts, R. Cornelis, H.Crews, OFX. Donard. Trace Element Speciation for Environment, Food and Health, Royal Society of Chemistry. 2001; p: 300.
• [49] Vitali, D., I. Vedrina Dragojević, and B. Šebečić. “Bioaccessibility of Ca, Mg, Mn and Cu from Whole Grain Tea-Biscuits: Impact of Proteins, Phytic Acid and Polyphenols.” Food Chemistry. 2008;110 (1). Food Chem: 62–68. doi:10.1016/j.foodchem.2008.01.056.
• [50] Brun, L. A., J. Maillet, P. Hinsinger, and M. Pépin. “Evaluation of Copper Availability to Plants in Copper-Contaminated Vineyard Soils.” Environmental Pollution. 2001; 111 (2). Elsevier Ltd: 293–302. doi:10.1016/S0269-7491(00)00067-1.
• [51] Akguc, N., I. I. Ozyigit, U. Yasar, Z. Leblebici, and C. Yarci. “Use of Pyracantha Coccinea Roem. as a Possible Biomonitor for the Selected Heavy Metals.” International Journal of Environmental Science and Technology. 2010; 7 (3): 427–434. doi:10.1007/BF03326152.
• [52] Taha, K. K., Mona I. Shmou, Maisoon H. Osman, and M. H. Shayoub. “Soil-Plant Transfer and Accumulation Factors for Trace Elements at the Blue and White Niles.” 2013.
• [53] Matos-Reyes, M. N., M. L. Cervera, R. C. Campos, and M. de la Guardia. “Total Content of As, Sb, Se, Te and Bi in Spanish Vegetables, Cereals and Pulses and Estimation of the Contribution of These Foods to the Mediterranean Daily Intake of Trace Elements.” Food Chemistry. 2010; 122 (1). Elsevier Ltd: 188–194. doi:10.1016/j.foodchem.2010.02.052.
• [54] Varhan Oral, E., Ö. Tokul-Ölmez, İ. Yener, M. Firat, Z. Tunay, P. Terzioğlu, et al. Trace Elemental Analysis of Allium Species by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) wit0h Multivariate Chemometrics. Analytical Letters. 2019; 52, no. 2: 320–336. doi:10.1080/00032719.2018.1460376.
• [55] Choudhury, R Paul, and A N Garg. “Variation in Essential, Trace and Toxic Elemental Contents in Murraya Koenigii-A Spice and Medicinal Herb from Different Indian States.”; 2021. Accessed May 15. doi:10.1016/j.foodchem.2007.02.013.
• [56] Saglam, C. Heavy Metal Accumulation in the Edible Parts of Some Cultivated Plants and Media Samples from a Volcanic Region in Southern Turkey. Ekoloji; 2013. 22(86): 1-8.
• [57] Dubale, A.A., B.S. Chandravanshi, and K.F. Gebremariam. Levels of Major and Trace Metals in the Leaves and Infusions of Croton Macrostachyus. Bulletin of the Chemical Society of Ethiopia. 2015; 29, no. 1 (January 18): 11–26. doi:10.4314/bcse.v29i1.2.
• [58] Soydemir, E. Determination of Mercury in 2.5 PM Air Particles by Solid Sampling High Resolution Electrothermal Atomic Absorption Spectrophotometer. Istanbul Technical University Institute of Science and Technology, Master Thesis, 5-7. 2013.
• [59] Caglarirmak N., AZ. Hepcimen. Effect of Heavy Metal Soil Pollution on Food Chain and Human Health. Review Paper, Academic Food. 2010; 8 (2): 31-35.
• [60] WHO (World Health Organization). Depleted Uranium: Sources, Exposure and Health Effects—Executive Summary; 2001.
• [61] Terzioǧlu, P., S. Yücel, and M. Öztürk. Application of Box-Behnken Design for Modeling of Lead Adsorption onto Unmodified and NaCl-Modified Zeolite NaA Obtained from Biosilica. Water Science and Technology. 2017; 75, no. 2 (January 1): 358–365. doi:10.2166/wst.2016.526.
• [62] Kumar Sharma, R., M. Agrawal, and F. Marshall. Heavy Metal Contamination of Soil and Vegetables in Suburban Areas of Varanasi, India. Ecotoxicology and Environmental Safety. 2007;66, no. 2 (February): 258–266. doi:10.1016/j.ecoenv.2005.11.007.
• [63] Ražić, S., A. Onjia, and B. Potkonjak. Trace Elements Analysis of Echinacea Purpurea - Herbal Medicinal. Journal of Pharmaceutical and Biomedical Analysis. 2003;33, no. 4 (November 24): 845–850.doi:10.1016/S0731-7085(03)00338-8.
• [64] Chauhan, R.P., and A. Kumar. Soil to Plant Transfer of Alpha Activity in Potato Plants: Impact of Phosphate Fertilizers. Journal of Environmental Health Science and Engineering. 2015;13, no. 1 (December 16): 45 doi:10.1186/s40201-015-0200-4