Investigation of Biochemical Parameters in Cattle with Postpartum Hypophosphatemia

Abstract

Transition period, which encompasses the ±21 day process from calving, is an important period for dairy cattle that requires significant metabolic adaptations. One of the most important causes of diseases during this period is known to be disturbances in mineral metabolism. Even in clinically healthy dairy cows, hypophosphatemia is reported to be over 50% on the day of calving and 10-15% during the first two weeks postpartum. In the presented study, it is aimed to evaluate the changes in metabolic profile parameters in dairy cattle developing hypophosphatemia. In the study, the group of 25 dairy cows with hypophosphatemia in the fresh period formed the experimental group, while the control group consisted of 10 dairy cows determined to be healthy in general clinical examination and biochemical analyses. When examining the metabolic profile parameters, in the hypophosphatemia group, compared to the control group, calcium (p<0.037), potassium (p<0.013), albumin (p<0.002), and ALT (p<0.031) levels were found to be low, while the NEFA (p<0.001) concentration was found to be high. It has been shown that serum phosphorus concentrations may decrease at the beginning of lactation and that this condition may affect the metabolic status of the animals.

Keywords

• Dairy cattle
• Hypophosphatemia
• Biochemical analysis

Postpartum Dönem Hipofosfatemi Şekillenen Sığırlarda Biyokimyasal Parametrelerin Araştırılması

Abstract

Geçiş dönemi buzağılama gününde ±21 günlük süreci kapsayan önemli metabolik adaptasyonlar gerektiren sütçü sığırlar için önemli bir periyottur. Bu dönemdeki hastalıkların en önemli sebeplerinden biri mineral metabolizmasındaki bozulmalar olarak bilinmektedir. Klinik olarak sağlıklı süt ineklerinde bile buzağılama gününde %50’nin üzerinde, postpartum ilk iki haftada %10-15 oranında hipofosfatemi bildirilmektedir. Sunulan çalışmada hipofosfatemi gelişen sütçü sığırlarda metabolik profil parametrelerinin değişimlerinin değerlendirilmesi amaçlanmaktadır. Çalışmada fresh döneminde bulunan 25 adet sütçü sığır hipofosfatemi grubunu, genel klinik muayenede ve biyokimyasal analizlerde sağlıklı olduğu belirlenen 10 sütçü sığır kontrol grubunu oluşturdu. Metabolik profil parametreleri incelendiğinde hipofosfatemi grubunda kontrol grubuna kıyasla kalsiyum (p<0.037), potasyum (p<0.013), albümin (p<0.002), ALT (p<0.031) düzeyleri düşük, NEFA (p<0.001) konsantrasyonu ise yüksek bulundu. Laktasyonun başlangıcında serum fosfor konsantrasyonlarının azalabileceği ve bu durumun hayvanların metabolik durumunu etkileyebileceği gösterildi.

Keywords

• Sütçü sığır
• Hipofosfatemi
• Biyokimyasal analiz

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