Research Article

The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases

Volume: 16 Number: 1 March 25, 2025
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The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases

Abstract

Aim: This study aims to assess the diagnostic accuracy of multi-slice computed tomography (CT) colonography in detecting colorectal lesions. Material and Methods: 22 patients with confirmed or clinically suspected colorectal pathology underwent multi-slice CT colonography followed by conventional colonoscopy on the same day. The diagnostic findings of multi-slice CT colonography were compared with those obtained from conventional colonoscopy. Results: Of 22 patients who underwent CT colonography, 10 (45%) were evaluated as normal. Bowel wall thickening was observed in 4 patients (18%), while polypoid lesions were detected in 8 (36%). Among the 9 polypoid lesions identified through conventional colonoscopy, 8 were also detected by CT colonography. The overall sensitivity of CT colonography for polypoid lesions, regardless of size, was 89%. Sensitivity was 50% for lesions smaller than 1 cm and 100% for lesions larger than 1 cm. When polypoid lesions were evaluated according to their histology, the sensitivity of CT Colonography was found to be 50% in tubular adenoma, 100% in tubulovillous adenoma, and 100% in adenocarcinoma. Conclusion: The sensitivity of CT colonography for detecting colorectal polypoid lesions was found to be 89%. These results indicate that CT colonography is a valuable diagnostic modality for comprehensive evaluation of the colon. CT colonography represents a viable alternative to traditional colorectal cancer screening methods due to its high sensitivity for detecting colorectal lesions, coupled with its relatively safe and minimally invasive nature.

Keywords

Ethical Statement

This thesis study was conducted with the permission of the Radiology Department of Social Security Institution Dışkapı Ankara Training Hospital (ethical approval date: 18.07.2022 no: 08)

References

  1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–49.
  2. Duan B, Zhao Y, Bai J, Wang J, Duan X, Luo X, et al. Colorectal Cancer: An Overview. In: Morgado-Diaz JA, editor. Gastrointestinal Cancers [Internet]. Brisbane (AU): Exon Publications; 2022 Sep 30. Chapter 1.
  3. Chung DJ, Huh KC, Choi WJ, Kim JK. CT colonography using 16-MDCT in the evaluation of colorectal cancer. AJR Am J Roentgenol. 2005;184(1):98–103.
  4. Sha J, Chen J, Lv X, Liu S, Chen R, Zhang Z. Computed tomography colonography versus colonoscopy for detection of colorectal cancer: a diagnostic performance study. BMC Med Imaging. 2020;20(1):51.
  5. Zygulska AL, Pierzchalski P. Novel Diagnostic Biomarkers in Colorectal Cancer. Int J Mol Sci. 2022;23(2):852.
  6. Gupta S. Screening for Colorectal Cancer. Hematol Oncol Clin North Am. 2022;36(3):393-414.
  7. Spada C, Hassan C, Bellini D, Burling D, Cappello G, Carretero C,et al. Imaging alternatives to colonoscopy: CT colonography and colon capsule. European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline - Update 2020. Eur Radiol. 2021;31(5):2967-2982.
  8. Kadari M, Subhan M, Saji Parel N, Krishna PV, Gupta A, Uthayaseelan K, et al. CT Colonography and Colorectal Carcinoma: Current Trends and Emerging Developments. Cureus. 2022;14(5): e24916.

Details

Primary Language

English

Subjects

Radiology and Organ Imaging

Journal Section

Research Article

Publication Date

March 25, 2025

Submission Date

January 2, 2025

Acceptance Date

January 28, 2025

Published in Issue

Year 2025 Volume: 16 Number: 1

APA
Süer Doğan, İ., Çakmakçı Midia, E., Songür, Y., & Hekimoğlu, B. (2025). The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases. Turkish Journal of Clinics and Laboratory, 16(1), 27-33. https://doi.org/10.18663/tjcl.1603140
AMA
1.Süer Doğan İ, Çakmakçı Midia E, Songür Y, Hekimoğlu B. The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases. TJCL. 2025;16(1):27-33. doi:10.18663/tjcl.1603140
Chicago
Süer Doğan, İhsaniye, Esin Çakmakçı Midia, Yıldıran Songür, and Baki Hekimoğlu. 2025. “The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases”. Turkish Journal of Clinics and Laboratory 16 (1): 27-33. https://doi.org/10.18663/tjcl.1603140.
EndNote
Süer Doğan İ, Çakmakçı Midia E, Songür Y, Hekimoğlu B (March 1, 2025) The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases. Turkish Journal of Clinics and Laboratory 16 1 27–33.
IEEE
[1]İ. Süer Doğan, E. Çakmakçı Midia, Y. Songür, and B. Hekimoğlu, “The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases”, TJCL, vol. 16, no. 1, pp. 27–33, Mar. 2025, doi: 10.18663/tjcl.1603140.
ISNAD
Süer Doğan, İhsaniye - Çakmakçı Midia, Esin - Songür, Yıldıran - Hekimoğlu, Baki. “The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases”. Turkish Journal of Clinics and Laboratory 16/1 (March 1, 2025): 27-33. https://doi.org/10.18663/tjcl.1603140.
JAMA
1.Süer Doğan İ, Çakmakçı Midia E, Songür Y, Hekimoğlu B. The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases. TJCL. 2025;16:27–33.
MLA
Süer Doğan, İhsaniye, et al. “The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases”. Turkish Journal of Clinics and Laboratory, vol. 16, no. 1, Mar. 2025, pp. 27-33, doi:10.18663/tjcl.1603140.
Vancouver
1.İhsaniye Süer Doğan, Esin Çakmakçı Midia, Yıldıran Songür, Baki Hekimoğlu. The Diagnostic Value of Virtual Colonoscopy in Colonic Diseases. TJCL. 2025 Mar. 1;16(1):27-33. doi:10.18663/tjcl.1603140