Research Article
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Early catastrophic proximal junctional fracture after spinal instrumentation in geriatric patients

Year 2025, Volume: 16 Issue: 3, 586 - 592, 30.09.2025
https://doi.org/10.18663/tjcl.1783563

Abstract

Aim: The purpose of this investigation was to evaluate the effectiveness of pedicle screw fixation and bilateral hooks in the prevention of proximal junctional kyphosis (PJK) and proximal junctional proximal junctional insufficiency/failure (PJI) among high-risk elderly patients.
Material and Methods: This retrospective study included 56 high-risk elderly patients who underwent long-segment spinal instrumentation and fusion between 2021 and 2024. Group A consisted of 26 patients who received pedicle screw fixation, while Group B comprised 30 patients who underwent bilateral hook placement during surgery. The primary outcomes were the development of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF). Preoperative and postoperative assessments, including the Visual Analog Scale (VAS), the Oswestry Disability Index (ODI) for functional status, and the 36-Item Short Form Health Survey (SF-36) for quality of life, were retrieved from patient medical records.
Results: PJK occurred in 26.9% of the pedicle screw group (Group A) compared with 6.7% in the bilateral-hook group (Group B), while PJF rates were 19.2% and 3.3%, respectively (p < 0.05). Neurologic deficits developed in 11.5% in Group A and 3.3% in Group B (p = 0.044). Significant improvements were observed in postoperative VAS, ODI, and SF-36 scores in both groups, with Group B showing better outcomes (p < 0.001). Age over 70 years (OR 1.68–2.24), T-score ≤ −2.5 (OR 1.92), number of previous operations (OR 1.64–2.86), an upper-instrumented vertebra at T10 or above (OR 1.78), and pedicle screw fixation (OR 2.84) were independent risk factors for increasing the risk of developing PJK/PJF.
Conclusion: This study indicates that the use of bilateral hooks reduces the risk of proximal junctional kyphosis and proximal junctional fracture in elderly high-risk patients after spinal fusion compared with pedicle screw fixation alone. Bilateral-hook placement was associated with lower complication rates and better clinical outcomes in terms of pain reduction, functional improvement, and return to daily activities.

Ethical Statement

This study was approved by the Ethics Committee of Eskişehir City Hospital (Date: 29.12.2023, No: KU.FR.08.04).

References

  • Onafowokan OO, Lafage R, Tretiakov P, et al. Comparative Analysis of Outcomes in Adult Spinal Deformity Patients with Proximal Junctional Kyphosis or Failure Initially Fused to Upper Versus Lower Thoracic Spine. Journal of clinical medicine. 2024;13(24):7722.
  • Hyun SJ, Lee BH, Park JH, Kim KJ, Jahng TA, and Kim HJ. Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery. Korean J Spine. 2017;14(4):126-32.
  • Nguyen NL, Kong CY, and Hart RA. Proximal junctional kyphosis and failure-diagnosis, prevention, and treatment. Curr Rev Musculoskelet Med. 2016;9(3):299-308.
  • Lu Z, Wang T, Wei W, Liu J, Ji X, and Zhao Y. Risk Factors of Proximal Junctional Failure After Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis. World Neurosurg. 2025;193:1-7.
  • Denis F, Sun EC, and Winter RB. Incidence and risk factors for proximal and distal junctional kyphosis following surgical treatment for Scheuermann kyphosis: minimum five-year follow-up. Spine (Phila Pa 1976). 2009;34(20):E729-34.
  • Lee J and Park YS. Proximal Junctional Kyphosis: Diagnosis, Pathogenesis, and Treatment. Asian Spine J. 2016;10(3):593-600.
  • Hart RA, McCarthy I, Ames CP, Shaffrey CI, Hamilton DK, and Hostin R. Proximal junctional kyphosis and proximal junctional failure. Neurosurg Clin N Am. 2013;24(2):213-8.
  • Bae J, Theologis AA, Strom R, et al. Comparative analysis of 3 surgical strategies for adult spinal deformity with mild to moderate sagittal imbalance. J Neurosurg Spine. 2018;28(1):40-49.
  • Han S, Hyun SJ, Kim KJ, Jahng TA, and Kim HJ. Comparative Study Between Cobalt Chrome and Titanium Alloy Rods for Multilevel Spinal Fusion: Proximal Junctional Kyphosis More Frequently Occurred in Patients Having Cobalt Chrome Rods. World Neurosurg. 2017;103:404-09.
  • Kim HJ, Lenke LG, Shaffrey CI, Van Alstyne EM, and Skelly AC. Proximal junctional kyphosis as a distinct form of adjacent segment pathology after spinal deformity surgery: a systematic review. Spine (Phila Pa 1976). 2012;37(22 Suppl):S144-64.
  • Yagi M, Yamanouchi K, Fujita N, Funao H, and Ebata S. Proximal Junctional Failure in Adult Spinal Deformity Surgery: An In-depth Review. Neurospine. 2023;20(3):876-89.
  • Anand N, Agrawal A, Ravinsky R, Khanderhoo B, Kahwaty S, and Chung A. The prevalence of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) in patients undergoing circumferential minimally invasive surgical (cMIS) correction for adult spinal deformity: long-term 2- to 13-year follow-up. Spine Deform. 2021;9(5):1433-41.
  • Doodkorte RJP, Vercoulen TFG, Roth AK, de Bie RA, and Willems PC. Instrumentation techniques to prevent proximal junctional kyphosis and proximal junctional failure in adult spinal deformity correction-a systematic review of biomechanical studies. Spine J. 2021;21(5):842-54.
  • Reames DL, Kasliwal MK, Smith JS, Hamilton DK, Arlet V, and Shaffrey CI. Time to development, clinical and radiographic characteristics, and management of proximal junctional kyphosis following adult thoracolumbar instrumented fusion for spinal deformity. J Spinal Disord Tech. 2015;28(2):E106-14.
  • Nabiuni M, Hatam J, and Haghbin S. Protective factors of preventing proximal junctional kyphosis as the most common complication of adult spinal deformity surgery. Iranian Journal of Neurosurgery. 2023;9:0-0.
  • Rabinovich EP, Snyder MH, McClure JJ, et al. Posterior Polyethylene Tethers Reduce Occurrence of Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity: A Retrospective Analysis. Neurosurgery. 2021;89(2):227-35.
  • Kaufmann A, Claus C, Tong D, et al. Multilevel Stabilization Screws Prevent Proximal Junctional Failure and Kyphosis in Adult Spinal Deformity Surgery: A Comparative Cohort Study. Oper Neurosurg. 2022;22(3):150-57.
  • Vercoulen TFG, Doodkorte RJP, Roth A, de Bie R, and Willems PC. Instrumentation Techniques to Prevent Proximal Junctional Kyphosis and Proximal Junctional Failure in Adult Spinal Deformity Correction: A Systematic Review of Clinical Studies. Global Spine J. 2022;12(6):1282-96.
  • Safaee MM, Osorio JA, Verma K, et al. Proximal Junctional Kyphosis Prevention Strategies: A Video Technique Guide. Oper Neurosurg. 2017;13(5):581-85.
  • Helgeson MD, Shah SA, Newton PO, et al. Evaluation of proximal junctional kyphosis in adolescent idiopathic scoliosis following pedicle screw, hook, or hybrid instrumentation. Spine (Phila Pa 1976). 2010;35(2):177-81.
  • Katayanagi J, Konuma H, Yanase T, et al. Independent Risk Factors of Proximal Junctional Kyphosis with Vertebral Fracture After Spinal Long Fusion: Survivorship Analysis of Adult Spinal Deformity Surgery Patients. World Neurosurg. 2024;188:e597-e605.
  • Han X and Ren J. Risk factors for proximal junctional kyphosis in adult spinal deformity after correction surgery: A systematic review and meta-analysis. Acta Orthop Traumatol Turc. 2022;56(3):158-65.
  • Sakuma T, Kotani T, Akazawa T, et al. Incidence, Risk Factors, and Prevention Strategy for Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery. Spine Surg Relat Res. 2021;5(2):75-80.
  • Cammarata M, Aubin CE, Wang X, and Mac-Thiong JM. Biomechanical risk factors for proximal junctional kyphosis: a detailed numerical analysis of surgical instrumentation variables. Spine (Phila Pa 1976). 2014;39(8):E500-7.
  • Solomon E, Bronheim RS, and Hassanzadeh H. Prevention of Proximal Junctional Kyphosis Using Proximal Fixation Techniques. Int J Spine Surg. 2023;17(S2):S47-S57.

Geriatrik hastalarda spinal enstrümantasyon sonrası erken katastrofik proksimal junksiyonel kırık

Year 2025, Volume: 16 Issue: 3, 586 - 592, 30.09.2025
https://doi.org/10.18663/tjcl.1783563

Abstract

Amaç: Bu araştırmanın amacı, yüksek riskli yaşlı hastalarda proksimal junksiyonel kifoz (PJK) ve proksimal junksiyonel yetmezlik/fraktür (PJF) gelişiminin önlenmesinde pedikül vida fiksasyonu ve bilateral kanca desteğinin etkinliğini değerlendirmekti.
Gereç ve Yöntem: Bu retrospektif çalışmaya 2021–2024 yılları arasında uzun-segment spinal enstrümantasyon ve füzyon uygulanan 56 yüksek riskli yaşlı hasta dahil edildi. Grup A, pedikül vida fiksasyonu uygulanan 26 hastadan; Grup B ise cerrahi sırasında bilateral kanca yerleştirilmesi uygulanan 30 hastadan oluşmaktaydı. Birincil sonuçlar PJK ve PJF gelişimiydi. Hastaların preoperatif ve postoperatif dönemlerde Görsel Analog Skala (VAS), fonksiyon için Oswestry Engellilik İndeksi (ODI) ve yaşam kalitesi için 36 Maddelik Kısa Form Sağlık Anketi (SF-36); değerlendirmeleri hasta dosyalarından toplandı.
Bulgular: Pedikül vida grubunda (Grup A) PJK %26,9 oranında görülürken, bu oran bilateral-kanca grubunda (Grup B) %6,7 idi. PJF oranları ise sırasıyla %19,2 ve %3,3 olarak saptandı (p < 0,05). Nörolojik defisit gelişimi Grup A’da %11,5, Grup B’de %3,3 idi (p = 0,044). Her iki grupta da postoperatif VAS, ODI ve SF-36 skorlarında anlamlı iyileşmeler gözlendi; bununla birlikte Grup B daha iyi sonuçlar gösterdi (p < 0,001). Yetmiş yaş üstü olmak (OR: 1,68–2,24), T-skorunun ≤ −2,5 olması (OR: 1,92), geçirilmiş operasyon sayısı (OR: 1,64–2,86), üst enstrümante vertebranın T10 veya daha üst seviyede olması (OR: 1,78) ve pedikül vida fiksasyonu (OR: 2,84) PJK/PJF geliştirme riskini artıran faktörlerdi.
Sonuçlar: Bu çalışma, bilateral kanca kullanımının, yalnız pedikül vida fiksasyonuna kıyasla, spinal füzyon sonrası yüksek riskli yaşlı hastalarda PJK ve PJF riskini azalttığını göstermektedir. Bilateral-kanca yerleştirilmesi; ağrının azaltılması, fonksiyonel iyileşme ve günlük aktivitelere dönüş açısından daha düşük komplikasyon oranları ve daha iyi klinik sonuçlar ile ilişkiliydi.

References

  • Onafowokan OO, Lafage R, Tretiakov P, et al. Comparative Analysis of Outcomes in Adult Spinal Deformity Patients with Proximal Junctional Kyphosis or Failure Initially Fused to Upper Versus Lower Thoracic Spine. Journal of clinical medicine. 2024;13(24):7722.
  • Hyun SJ, Lee BH, Park JH, Kim KJ, Jahng TA, and Kim HJ. Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery. Korean J Spine. 2017;14(4):126-32.
  • Nguyen NL, Kong CY, and Hart RA. Proximal junctional kyphosis and failure-diagnosis, prevention, and treatment. Curr Rev Musculoskelet Med. 2016;9(3):299-308.
  • Lu Z, Wang T, Wei W, Liu J, Ji X, and Zhao Y. Risk Factors of Proximal Junctional Failure After Adult Spinal Deformity Surgery: A Systematic Review and Meta-Analysis. World Neurosurg. 2025;193:1-7.
  • Denis F, Sun EC, and Winter RB. Incidence and risk factors for proximal and distal junctional kyphosis following surgical treatment for Scheuermann kyphosis: minimum five-year follow-up. Spine (Phila Pa 1976). 2009;34(20):E729-34.
  • Lee J and Park YS. Proximal Junctional Kyphosis: Diagnosis, Pathogenesis, and Treatment. Asian Spine J. 2016;10(3):593-600.
  • Hart RA, McCarthy I, Ames CP, Shaffrey CI, Hamilton DK, and Hostin R. Proximal junctional kyphosis and proximal junctional failure. Neurosurg Clin N Am. 2013;24(2):213-8.
  • Bae J, Theologis AA, Strom R, et al. Comparative analysis of 3 surgical strategies for adult spinal deformity with mild to moderate sagittal imbalance. J Neurosurg Spine. 2018;28(1):40-49.
  • Han S, Hyun SJ, Kim KJ, Jahng TA, and Kim HJ. Comparative Study Between Cobalt Chrome and Titanium Alloy Rods for Multilevel Spinal Fusion: Proximal Junctional Kyphosis More Frequently Occurred in Patients Having Cobalt Chrome Rods. World Neurosurg. 2017;103:404-09.
  • Kim HJ, Lenke LG, Shaffrey CI, Van Alstyne EM, and Skelly AC. Proximal junctional kyphosis as a distinct form of adjacent segment pathology after spinal deformity surgery: a systematic review. Spine (Phila Pa 1976). 2012;37(22 Suppl):S144-64.
  • Yagi M, Yamanouchi K, Fujita N, Funao H, and Ebata S. Proximal Junctional Failure in Adult Spinal Deformity Surgery: An In-depth Review. Neurospine. 2023;20(3):876-89.
  • Anand N, Agrawal A, Ravinsky R, Khanderhoo B, Kahwaty S, and Chung A. The prevalence of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) in patients undergoing circumferential minimally invasive surgical (cMIS) correction for adult spinal deformity: long-term 2- to 13-year follow-up. Spine Deform. 2021;9(5):1433-41.
  • Doodkorte RJP, Vercoulen TFG, Roth AK, de Bie RA, and Willems PC. Instrumentation techniques to prevent proximal junctional kyphosis and proximal junctional failure in adult spinal deformity correction-a systematic review of biomechanical studies. Spine J. 2021;21(5):842-54.
  • Reames DL, Kasliwal MK, Smith JS, Hamilton DK, Arlet V, and Shaffrey CI. Time to development, clinical and radiographic characteristics, and management of proximal junctional kyphosis following adult thoracolumbar instrumented fusion for spinal deformity. J Spinal Disord Tech. 2015;28(2):E106-14.
  • Nabiuni M, Hatam J, and Haghbin S. Protective factors of preventing proximal junctional kyphosis as the most common complication of adult spinal deformity surgery. Iranian Journal of Neurosurgery. 2023;9:0-0.
  • Rabinovich EP, Snyder MH, McClure JJ, et al. Posterior Polyethylene Tethers Reduce Occurrence of Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity: A Retrospective Analysis. Neurosurgery. 2021;89(2):227-35.
  • Kaufmann A, Claus C, Tong D, et al. Multilevel Stabilization Screws Prevent Proximal Junctional Failure and Kyphosis in Adult Spinal Deformity Surgery: A Comparative Cohort Study. Oper Neurosurg. 2022;22(3):150-57.
  • Vercoulen TFG, Doodkorte RJP, Roth A, de Bie R, and Willems PC. Instrumentation Techniques to Prevent Proximal Junctional Kyphosis and Proximal Junctional Failure in Adult Spinal Deformity Correction: A Systematic Review of Clinical Studies. Global Spine J. 2022;12(6):1282-96.
  • Safaee MM, Osorio JA, Verma K, et al. Proximal Junctional Kyphosis Prevention Strategies: A Video Technique Guide. Oper Neurosurg. 2017;13(5):581-85.
  • Helgeson MD, Shah SA, Newton PO, et al. Evaluation of proximal junctional kyphosis in adolescent idiopathic scoliosis following pedicle screw, hook, or hybrid instrumentation. Spine (Phila Pa 1976). 2010;35(2):177-81.
  • Katayanagi J, Konuma H, Yanase T, et al. Independent Risk Factors of Proximal Junctional Kyphosis with Vertebral Fracture After Spinal Long Fusion: Survivorship Analysis of Adult Spinal Deformity Surgery Patients. World Neurosurg. 2024;188:e597-e605.
  • Han X and Ren J. Risk factors for proximal junctional kyphosis in adult spinal deformity after correction surgery: A systematic review and meta-analysis. Acta Orthop Traumatol Turc. 2022;56(3):158-65.
  • Sakuma T, Kotani T, Akazawa T, et al. Incidence, Risk Factors, and Prevention Strategy for Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery. Spine Surg Relat Res. 2021;5(2):75-80.
  • Cammarata M, Aubin CE, Wang X, and Mac-Thiong JM. Biomechanical risk factors for proximal junctional kyphosis: a detailed numerical analysis of surgical instrumentation variables. Spine (Phila Pa 1976). 2014;39(8):E500-7.
  • Solomon E, Bronheim RS, and Hassanzadeh H. Prevention of Proximal Junctional Kyphosis Using Proximal Fixation Techniques. Int J Spine Surg. 2023;17(S2):S47-S57.
There are 25 citations in total.

Details

Primary Language English
Subjects Brain and Nerve Surgery (Neurosurgery)
Journal Section Research Article
Authors

Celal Özbek Çakır 0000-0002-3618-6033

Murat Baloglu 0000-0001-7727-1982

Publication Date September 30, 2025
Submission Date September 13, 2025
Acceptance Date September 28, 2025
Published in Issue Year 2025 Volume: 16 Issue: 3

Cite

APA Çakır, C. Ö., & Baloglu, M. (2025). Early catastrophic proximal junctional fracture after spinal instrumentation in geriatric patients. Turkish Journal of Clinics and Laboratory, 16(3), 586-592. https://doi.org/10.18663/tjcl.1783563
AMA Çakır CÖ, Baloglu M. Early catastrophic proximal junctional fracture after spinal instrumentation in geriatric patients. TJCL. September 2025;16(3):586-592. doi:10.18663/tjcl.1783563
Chicago Çakır, Celal Özbek, and Murat Baloglu. “Early Catastrophic Proximal Junctional Fracture After Spinal Instrumentation in Geriatric Patients”. Turkish Journal of Clinics and Laboratory 16, no. 3 (September 2025): 586-92. https://doi.org/10.18663/tjcl.1783563.
EndNote Çakır CÖ, Baloglu M (September 1, 2025) Early catastrophic proximal junctional fracture after spinal instrumentation in geriatric patients. Turkish Journal of Clinics and Laboratory 16 3 586–592.
IEEE C. Ö. Çakır and M. Baloglu, “Early catastrophic proximal junctional fracture after spinal instrumentation in geriatric patients”, TJCL, vol. 16, no. 3, pp. 586–592, 2025, doi: 10.18663/tjcl.1783563.
ISNAD Çakır, Celal Özbek - Baloglu, Murat. “Early Catastrophic Proximal Junctional Fracture After Spinal Instrumentation in Geriatric Patients”. Turkish Journal of Clinics and Laboratory 16/3 (September2025), 586-592. https://doi.org/10.18663/tjcl.1783563.
JAMA Çakır CÖ, Baloglu M. Early catastrophic proximal junctional fracture after spinal instrumentation in geriatric patients. TJCL. 2025;16:586–592.
MLA Çakır, Celal Özbek and Murat Baloglu. “Early Catastrophic Proximal Junctional Fracture After Spinal Instrumentation in Geriatric Patients”. Turkish Journal of Clinics and Laboratory, vol. 16, no. 3, 2025, pp. 586-92, doi:10.18663/tjcl.1783563.
Vancouver Çakır CÖ, Baloglu M. Early catastrophic proximal junctional fracture after spinal instrumentation in geriatric patients. TJCL. 2025;16(3):586-92.