The Effects of Type II Diabetes Mellitus on Renal Parameters with Hypertensive Patients: Comparative Study

Year 2017, , 88 - 92, 20.06.2017

Hamza Aslanhan Ahmet Yılmaz

https://doi.org/10.21763/tjfmpc.317779

Abstract

Objective:
Hypertension and diabetes mellitus are two groups of diseases common in society
and increase the morbidity and mortality by affecting many systems. The aim of
this study is to research renal functions of patients diagnosed with
hypertension and type 2 diabetes mellitus in addition to hypertension and to
evaluate by comparing the effects of these diseases on kidney.  Method: The 85 hypertension patients and
85 diabetes mellitus and hypertension patients, totally 170 patients, between
35-70 ages involved in this study by retrospectively screening the archive
files of internal medicine and diabetes outpatient clinics. Clinical findings
and demographic features have been noted by screening the patient files in both
groups. Results: The rate of albuminuria was significantly higher in
diabetes mellitus and hypertension group (30.6%) than hypertension group
(16.5%) (p=0.047). In terms of the prevalence of cases whose glomerular
filtration rate <60mL/min/1.73m2, there was no significant difference
between HT group (2.4%) and diabetes mellitus and hypertension group (5.9%),
(p=0.44).  Conclusion: Type 2
diabetes mellitus; increases albuminuria in patients with hypertension. This
situation may be predictor of rapid progression to renal failure.

Amaç: Diabetes
mellitus ve hipertansiyon, toplumda yaygın olarak görülen iki hastalık grubu
olup bir çok sistemi etkileyerek, mortalite ve morbiditeyi arttırmaktadır. Bu
çalışmanın amacı, hipertansiyon ile hipertansiyona ek olarak Tip 2 diabetes mellitus
tanısı olan hastaların, renal fonksiyonlarının incelenmesi ve bu hastalıkların
böbrek üzerindeki etkilerinin karşılaştırılarak değerlendirilmesidir. Yöntem:
Çalışmaya, İstanbul Eğitim Araştırma Hastanesi dahiliye ve diyabet
polikliniklerinde ayaktan takip edilen, 35-70 yaşları arasında 85
hipertansiyon, 85 Tip 2 diabetes mellitus ve hipertansiyon tanılı, toplam 170
adet hasta arşiv dosyaları retrospektif olarak taranarak dahil edildi. Her iki
gruptan, klinik bulgular ve demografik özellikler taranarak kayıt edildi. Bulgular:
Tip 2 diabetes mellitus ve hipertansiyon grubunda, albüminüri oranı (%30,6),
hipertansiyon grubundan (%16,5) anlamlı olarak daha yüksekti (p=0,047).
Glomerüler filtrasyon hızı <60 mL/dk/1,73m² olanların oranı
açısından hipertansiyon grubu ile (% 2,4) Tip 2 diabetes mellitus ve
hipertansiyon grubu (%5,9) arasında anlamlı farklılık yoktu (p=0,44). Sonuç:
Tip 2 diabetes mellitus; hipertansiyon hastalarında albüminüriyi
arttırmaktadır. Bu durum, böbrek yetmezliğine hızlı gidişin bir görüntüsü
olabilir.

Keywords

Hypertension, Type 2 diabetes mellitus, Kidney disease

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