The Frequency and Some Causes of Anemia in Patients with Diabetes Mellitus with Normal Renal Function

Abstract

Introduction: Diabetes Mellitus (DM) is one of the most common chronic diseases worldwide according to World Health Organization reports. Anemia is common in patients with DM and anemia is a common hematological disorder in diabetic patients. In our study, we aimed to determine the anemia prevalence and the causes that affect anemia in patients with DM with normal renal function. Materials and Methods: Patients with DM who applied to Eskişehir Osmangazi University Medical Faculty Hospital (the clinics of Family Medicine and Internal Medicine) was included in our study and 229 patients with DM who were not diagnosed with renal dysfunction were included in our study within the last 6 months examinations. Laboratory results that were reviewed in the last 6 months were retrospectively screened and recorded. The hemoglobin (Hb) limit values were evaluated as 12 grams/deciliter (g/dl) in females and 13 g/dl in males and patients with Hb levels below these values were accepted as anemia. The data obtained at the end of the study were analyzed by using SPSS package program. Results: DM patients with normal renal function were included in the study. %25.8 (n=59) of patients had anemia. While 20.3% of the anemia was microcytic anemia, 79.7% was non-microcytic anemia (macrocytic and normocytic anemia). Iron deficiency was found in 57.1% (n = 32), while B12 deficiency was found in 11.8% (n = 7) and folic acid deficiency was found in 3.3% (n = 2) of patients with anemia. Iron deficiency was found in 9.9% (n = 14) of DM patients without anemia. Conclusion: Iron deficiency is the most diagnosed reason of anemia in DM patients. As the clinicians, we can provide early diagnosis and treatment of anemia in diabetic patients especially iron deficiency and we can improve the quality of life of patients and decrease morbidity and mortality.

Keywords

• Anemia
• Diabetes mellitus
• diabetic complication

Böbrek Fonksiyonları Normal Olan Diyabetes Mellitus Hastalarında Anemi Sıklığı ve Bazı Nedenleri

Abstract

Giriş: Diyabetes Mellitus Dünya Sağlık Örgütü raporlarına göre tüm dünyada en sık rastlanan kronik hastalıkların başında gelmektedir. Diyabetes Mellitus’u olan hastalarda anemi yaygındır ve anemi, diyabetik hastalarda sık görülen hematolojik bozukluklardandır. Çalışmamızla, böbrek fonksiyonları normal olan Diyabetes Mellitus hastalarında anemi sıklığını ve anemiyi etkileyen sebepleri belirlemeyi amaçladık. Materyal ve Metot: Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi Aile Hekimliği ve İç Hastalıkları polikliniklerine başvuran DM hastaları çalışmamıza dahil edilmiş olup, son 6 ay içinde yapılan muayenelerinde ve tetkiklerinde böbrek fonksiyon bozukluğu saptanmayan 229 DM hastası çalışmamıza dahil edilmiştir. Son 6 ayda çalışılan laboratuvar sonuçları retrospektif olarak tarandı ve kaydedildi. Hemoglobin (Hb) sınır değerleri kadınlarda 12 gram / desilitre (g / dl), erkeklerde 13 g / dl olarak değerlendirildi ve bu değerlerin altında Hb seviyeleri olan hastalar anemi olarak kabul edildi. Çalışma sonunda elde edilen veriler SPSS paket programı kullanılarak analiz edilmiştir. Bulgular: Toplam 229 böbrek fonksiyonları normal olan DM hastası çalışmaya dahil edilmiştir. Anemilerin %20.3’ü mikrositer anemi iken, %79.7’si mikrositer olmayan anemiydi. Anemisi olan hastaların %57.1’inde (n=32) demir eksikliği saptanırken, %11.8’inde (n=7) B12 eksikliği, %3.3’ünde (n=2) folik asit eksikliği saptanmıştır. Anemi saptanmayan DM hastalarının da %9.9’unda (n=14) demir eksikliği olduğu belirlenmiştir. Sonuç: Demir eksikliği, DM hastalarında en sık teşhis edilen anemi nedenidir. Klinisyenler olarak, özellikle demir eksikliği olan diyabetik hastalarda erken dönemde anemi tanısı ve tedavisini sağlayabiliriz ve hastaların yaşam kalitesini iyileştirebilir, morbidite ve mortaliteyi azaltabiliriz.

Keywords

• Anemi
• Diabetes mellitus
• diabetik komplikasyon

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