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Estetik Amaçlı Pigmente Lezyon Eksizyonu İçin Başvuran Hastaların Histopatolojik İnceleme Sonuçları ve Tedavi Yönetimi

Year 2020, Volume: 14 Issue: 3, 474 - 478, 20.09.2020
https://doi.org/10.21763/tjfmpc.693482

Abstract

Amaç: Pigmente cilt lezyonlarının birinci basamak sağlık kuruluşlarında çalışan hekimler tarafından tanınması ve eşlik edebilecek malign hastalıklar yönünden araştırılması büyük önem taşımaktadır. Özellikle baş ve boyun yerleşimli olan pigmente lezyonların kozmetik açıdan başarılı bir şekilde çıkarılması hastaların genel başvuru nedeni olmaktadır. Bu çalışmada kliniğimize estetik amaçlarla lezyonlarını aldırmak isteyen hastaların histopatolojik tanıları retrospektif olarak incelenmiş ve tedavi yönetimi irdelenmiştir. Gereç ve Yöntem: Çalışmaya kliniğimize Kasım 2018- Kasım 2019 tarihleri arasında pigmente lezyonlarını sadece estetik amaçlı aldırmak isteyen toplam 85 hasta dahil edildi. Tüm hastalar aynı cerrah tarafından opere edildi. Eksizyon sonrası tüm lezyonlar histopatolojik incelemeye gönderildi. Bulgular: Toplam 85 hastadan 129 lezyon çıkarıldı. Hastaların 37’si (%43,5) erkek; 48’i (%56,5) kadın idi. Hastaların ortalama yaşı 38,9 (14-94 yaş) idi. Lezyonların ortalama büyüklüğü 1,15 cm² (0,3-5,3 cm²) idi. Histopatolojik inceleme sonrası 11 değişik tipte pigmente lezyon patolojisi ortaya çıktı. İntradermal nevüs çıkarılan lezyonlar arasında görülen en sık patoloji sonucuydu (%38). Bunu sırasıyla Seboreik keratoz (%24) ve bazal hücreli karsinom (%22) izledi. Baş-boyun bölgesi çıkarılan tüm lezyonların en sık yerleşim yeri idi. İlk muayenede konan ön tanıyla lezyonların histopatolojik sonucu arasındaki uyumsuzluk toplam 5 hastada gözlenmiştir. Sonuç: Cilt lezyonları geniş bir yelpazede klinik pratiğimizde karşımıza çıkmaktadır. Hastanın ilk başvurusunda çıplak gözle muayene her zaman doğru sonuç vermese de ABCDE kriterlerinin bilinmesi bu aşamada kritik önemdedir. Çalışmamızda sadece kozmetik amaçlı başvuran hastaların dahil edildiği göz önünde bulundurulduğunda hastaların dörtte birinin malign deri kanseri teşhisi aldığını ve bu bağlamda bir halk sağlığı sorunu olarak deri kanseriyle ile ilgili kişilerin eğitiminin yaygınlaştırılması gerektiğini vurgulamak istiyoruz.

References

  • 1. Tanrıverdi MH, Turan E. Birinci Basamakta Epidermal Prekanseröz Lezyonlara Yaklaşım. Konuralp Tıp Dergisi 2010;2(1):53-56
  • 2. Trost JG, Applebaum DS, Orengo I. Common Adult Skin and Soft Tissue Lesions. Semin Plast Surg 2016; 30:98-107
  • 3. Yavuz GO, Yavuz IH. Melanositik Nevüsler. Van Tıp Dergisi 2014; 21(4):259-268
  • 4. Usatine RP, Smith MA, Mayeaux EJ Jr, Chumley HS. The Color Atlas and Synopsis of Familiy Medicine, 3e. McGraw Hill Education. 2019:168; 1038-45
  • 5. Lee EH, Nehal KS, Disa JJ. Benign and premalignant skin lesions. Plast Reconstr Surg. 2010;125(5):188e–198e
  • 6. Hafner C, Vogt T.Seborrheic keratosis. J Dtsch Dermatol Ges. 2008; 6:664–677
  • 7. Frerich, B., Prall, F. Basalzellkarzinom der Gesichts- und Kopfhaut. MKG-Chirurg.2018; 11, 49–63
  • 8. Agadayı E, Alsancak AD, Ustunal D et.al. Aile Hekimliği Polikliniğine Başvuran Hastalarda Malign Melanom Risk Faktörlerinin Değerlendirlmesi ve Güneşten Korunma Hakkında Tutumları. Konuralp Tıp Dergisi. 2017;9(3):1-6
  • 9. Ersen, B., Akin, S., Saki, M.C. et al. Clinical and histopathological analysis of 152 pigmented skin lesion excisions apart from melanocytic nevus due to cosmetic reasons. Eur J Plast Surg . 2015; 38, 273–78 (2015)
  • 10. Ersen, B., Akin, S., Sahin, A. et al. Clinical and histopathological analysis of 790 naevi excised from 509 patients due to cosmetic reasons. Eur J Plast Surg. 2015;38, 133–138
  • 11. Nazer MR, Hajihoseini M, Hatkehlouei MB,et al. Prevelance of pigmented Nevus in Sari, North of Iran. A retrospective Study on 719 Patients. Int J Sci Stud. 2017;5(7):217-20
  • 12. Rivers JK, MacLennan R, Kelly JW, et al. The eastern Australian childhood nevus study: prevalence of atypical nevi, congenital nevus-like nevi, and other pigmented lesions. Journal of the American Academy of Dermatology 1995; 32(6):957-63.
  • 13. Gallagher RP, Rivers JK, Yang CP et al. Melanocytic nevus density in Asian, Indo-Pakistani, and white children: the Vancouver Mole Study. Journal of the American Academy of Dermatology 1991; 25(3):507-12.
  • 14. Har-Shai Y, Hai N, Taran A, et al. Sensitivity and positive predictive values of presurgical clinical diagnosis of excised benign and malignant skin tumors: a prospective study of 835 lesions in 778 patients. Plast Reconstr Surg. 2001;108(7):1982–1989.
  • 15. Hallock GG, Lutz DA. Prospective study of the accuracy of the surgeon's diagnosis in 2000 excised skin tumors. Plast Reconstr Surg. 1998;101(5):1255–1261.

Histopathological Examination Results and Treatment Modalities of Patients After Pigmented Lesion Excision For Cosmetic Reasons

Year 2020, Volume: 14 Issue: 3, 474 - 478, 20.09.2020
https://doi.org/10.21763/tjfmpc.693482

Abstract

Objective: It is very important to recognize the pigmented skin lesions and accompanied malignant skin diseases by physicians working in primary health care facilities. The successful removal of pigmented lesions, especially in the head and neck region, is the general reason for patients admitted to aesthetic surgery clinics. In this study, histopathological diagnoses of the lesions removed for aesthetic purposes are examined retrospectively and treatment management is reviewed. Material and Methods: A total of 85 patients who wanted to remove their pigmented lesions for only aesthetic purposes between November 2018 and November 2019 were included in this study. All patients were operated by the same surgeon. After excisional biopsy, all lesions were examined histopathologically. Results: 129 lesions were removed from 85 patients. 37 (43.5%) of the patients were male; 48 (56.5%) were women. The mean age of the patients was 38.9 (14-94 years). The average size of the lesions was 1.15 cm² (0.3-5.3 cm²). After histopathological examination, 11 different types of pigmented lesion pathology were obtained. Intradermal nevus was the most common pathology result among the lesions (38%). This was followed by Seborrheic keratosis (24%) and basal cell carcinoma (22%), respectively. The head and neck region was the most common location of all lesions that was removed. Incompatibility between the preliminary diagnosis and the histopathological results of the lesions was observed in 5 patients. Conclusion: Patients consult with a wide range of skin lesions in our clinical practice. Although the examination with the naked eye does not always give correct results at the first application of the patient, knowing the ABCDE criteria is critical at this stage. Considering the patients who refers for only cosmetic purposes are included in our study, we want to emphasize that one fourth of patients are diagnosed with malignant skin cancer and the education of people with skin cancer should be expanded as a public health problem.

References

  • 1. Tanrıverdi MH, Turan E. Birinci Basamakta Epidermal Prekanseröz Lezyonlara Yaklaşım. Konuralp Tıp Dergisi 2010;2(1):53-56
  • 2. Trost JG, Applebaum DS, Orengo I. Common Adult Skin and Soft Tissue Lesions. Semin Plast Surg 2016; 30:98-107
  • 3. Yavuz GO, Yavuz IH. Melanositik Nevüsler. Van Tıp Dergisi 2014; 21(4):259-268
  • 4. Usatine RP, Smith MA, Mayeaux EJ Jr, Chumley HS. The Color Atlas and Synopsis of Familiy Medicine, 3e. McGraw Hill Education. 2019:168; 1038-45
  • 5. Lee EH, Nehal KS, Disa JJ. Benign and premalignant skin lesions. Plast Reconstr Surg. 2010;125(5):188e–198e
  • 6. Hafner C, Vogt T.Seborrheic keratosis. J Dtsch Dermatol Ges. 2008; 6:664–677
  • 7. Frerich, B., Prall, F. Basalzellkarzinom der Gesichts- und Kopfhaut. MKG-Chirurg.2018; 11, 49–63
  • 8. Agadayı E, Alsancak AD, Ustunal D et.al. Aile Hekimliği Polikliniğine Başvuran Hastalarda Malign Melanom Risk Faktörlerinin Değerlendirlmesi ve Güneşten Korunma Hakkında Tutumları. Konuralp Tıp Dergisi. 2017;9(3):1-6
  • 9. Ersen, B., Akin, S., Saki, M.C. et al. Clinical and histopathological analysis of 152 pigmented skin lesion excisions apart from melanocytic nevus due to cosmetic reasons. Eur J Plast Surg . 2015; 38, 273–78 (2015)
  • 10. Ersen, B., Akin, S., Sahin, A. et al. Clinical and histopathological analysis of 790 naevi excised from 509 patients due to cosmetic reasons. Eur J Plast Surg. 2015;38, 133–138
  • 11. Nazer MR, Hajihoseini M, Hatkehlouei MB,et al. Prevelance of pigmented Nevus in Sari, North of Iran. A retrospective Study on 719 Patients. Int J Sci Stud. 2017;5(7):217-20
  • 12. Rivers JK, MacLennan R, Kelly JW, et al. The eastern Australian childhood nevus study: prevalence of atypical nevi, congenital nevus-like nevi, and other pigmented lesions. Journal of the American Academy of Dermatology 1995; 32(6):957-63.
  • 13. Gallagher RP, Rivers JK, Yang CP et al. Melanocytic nevus density in Asian, Indo-Pakistani, and white children: the Vancouver Mole Study. Journal of the American Academy of Dermatology 1991; 25(3):507-12.
  • 14. Har-Shai Y, Hai N, Taran A, et al. Sensitivity and positive predictive values of presurgical clinical diagnosis of excised benign and malignant skin tumors: a prospective study of 835 lesions in 778 patients. Plast Reconstr Surg. 2001;108(7):1982–1989.
  • 15. Hallock GG, Lutz DA. Prospective study of the accuracy of the surgeon's diagnosis in 2000 excised skin tumors. Plast Reconstr Surg. 1998;101(5):1255–1261.
There are 15 citations in total.

Details

Primary Language Turkish
Subjects Public Health, Environmental Health
Journal Section Orijinal Articles
Authors

Mehmet Can Şakı 0000-0001-9046-0710

Publication Date September 20, 2020
Submission Date February 24, 2020
Published in Issue Year 2020 Volume: 14 Issue: 3

Cite

Vancouver Şakı MC. Estetik Amaçlı Pigmente Lezyon Eksizyonu İçin Başvuran Hastaların Histopatolojik İnceleme Sonuçları ve Tedavi Yönetimi. TJFMPC. 2020;14(3):474-8.

English or Turkish manuscripts from authors with new knowledge to contribute to understanding and improving health and primary care are welcome. 


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