Eskişehir’deki Psikiyatrik Hastalarda Folat ve B12 Vitamin Seviyelerinin Değerlendirilmesi

Year 2018, Volume: 3 Issue: 1, 210 - 213, 29.06.2018

Fatih Kar Ceyhan Hacıoğlu Zeynep Küskü Kiraz Sema Uslu Güngör Kanbak

Abstract

Majör depresif bozukluk, kişinin sosyal işlevlerini ve
günlük yaşama dair etkinliklerini rahatsız edecek dereceye ulaşmış üzüntü,
melankoli veya keder durumudur. İlaç ile tedavisi ise özellikle kişilerin
tedaviye olumlu yanıt vermesi noktasında yetersiz ve iyileşme sürecinden uzakta
kalmaktadır. Son zamanlarda yapılan çalışmalar insanlarda meydana çıkan bu
depresif bozukluklarda beslenmede yer alan vitamin ve minerallerin önemli bir
rolü olduğuna yönelik kanıtlar ortaya koymaktadır. Merkezi sinir sistemi üzerindeki
etkileri sonucu Folat ve B12 vitamini bu noktada çalışmaların odağı olmaktadır.
Çalışmamızda Eskişehir Osmangazi Üniversitesi psikiyatri servisine başvuran
ayakta tedavi edilen hastaların Folat ve B12 vitamin düzeyleri incelendi. Bu
amaçla 2016 yılında psikiyatri servisine başvuran, B12 vitamin düzeyleri
ölçülen 343 hastanın ve Folat düzeyleri ölçülen 250 hastanın verileri
retrospektif olarak belirlendi. Elde edilen tüm veriler, SPSS 21 paket programı
ile istatistiksel olarak değerlendirildi. Değerlendirme sonucunda, Folat
eksikliğinin prevelansı %15,6, B12 vitamin eksikliğinin pravelansı ise %15,45
olarak bulunmuştur. Literatür ile uyumlu çıkan sonuçlarımız için majör depresif
bozukluk tanı ve tedavi sürecinde rutin olarak B12 vitamininin ve Folat düzeylerinin
takip edilmesi gerektiği söylenebilir. Özellikle antidepresan kullanımının
kısıtlanması ve semptomların giderilmesi noktasında yapılacak vitamin
takviyeleri ile olumlu sonuçlar alınabileceği yorumu yapılabilir.

Keywords

B12, Depresyon, Folat, Psikolojik bozukluklar

Evaluation of Folate and B12 Vitamin Levels in Psychiatric Patients in Eskişehir

Abstract

Major depressive disorder is sadness, melancholy, or
grief, which has reached a degree of disturbance for one's social functions and
activities of daily living. Drug treatment is inadequate at the situation where
people respond positively to treatment, and is far from the recovery process.
Recent studies have shown evidence that vitamins and minerals in the diet play
an important role in these depressive disorders that occur in humans. The
effects on the central nervous system are the resultant Folate and B12
vitamins. In our study, Folate and vitamin B12 levels of outpatients treated
with Eskişehir Osmangazi University psychiatric department were examined. For
this purpose, 343 patients with vitamin B12 levels and 250 patients with Folate
levels who were referred to a psychiatric service in 2016 were retrospectively
determined. All the data obtained were evaluated statistically by SPSS 21
package program. As a result of the evaluation, the prevalence of folate
deficiency was found to be 15.6% and that of vitamin B12 deficiency was found
to be 15.45%. For our results consistent with the literature, it can be said
that vitamin B12 and folate levels should be routinely monitored during the
diagnosis and treatment of major depressive disorder. Especially, antidepressant
use restriction and relieving symptoms can be interpreted as positive results
with vitamin supplements.

Keywords

B12, Depression, Folate, Psychological disorders

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