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Year 2025, Volume: 23 Issue: 2, 175 - 186, 09.08.2025

Abstract

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References

  • 1. Hugo J, Ganguli M. Dementia and cognitive impairment: epidemiology, diagnosis, and treatment. Clin Geriatr Med. 2014;30(3):421-442.
  • 2. Gale SA, Acar D, Daffner KR. Dementia. The American Journal of Medicine. 2018;131(10):1161-1169.
  • 3. WHO. Dementia. Geneva: WHO [online]. Available at https://www.who.int/news-room/fact-sheets/detail/ dementia on 31 March 2023. Accessed March 31, 2023.
  • 4. Livingston G, Sommerlad A, Orgeta V, et al. Dementia prevention, intervention, and care. Lancet. 2017;390(10113):2673-2734.
  • 5. Livingston G, Huntley J, Sommerlad A, et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission [published correction appears in Lancet. 2023 Sep 30;402(10408):1132]. Lancet. 2020;396(10248):413- 446.
  • 6. Sachdev PS, Blacker D, Blazer DG, et al. Classifying neurocognitive disorders: the DSM-5 approach. Nat Rev Neurol. 2014;10(11):634-642.
  • 7. Tampi RR, Jeste DV. Dementia Is More Than Memory Loss: Neuropsychiatric Symptoms of Dementia and Their Nonpharmacological and Pharmacological Management. Am J Psychiatry. 2022;179(8):528-543.
  • 8. GBD 2019 Dementia Forecasting Collaborators. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health. 2022;7(2):e105-e125.
  • 9. Türkiye İstatistik Kurumu (TUİK). Elderly Statistics, 2024 [online]. Available at https://data.tuik.gov.tr/Bulten/ Index?p=Elderly-Statistics-2024-54079. Accessed July 09, 2025.
  • 10. Gurvit H, Emre M, Tinaz S, et al. The prevalence of dementia in an urban Turkish population. Am J Alzheimers Dis Other Demen. 2008;23(1):67-76.
  • 11. Arslantaş D, Ozbabalik D, Metintaş S, et al. Prevalence of dementia and associated risk factors in Middle Anatolia, Turkey. J Clin Neurosci. 2009;16(11):1455-1459.
  • 12. Keskinoglu P, Giray H, Picakciefe M, Bilgic N, Ucku R. The prevalence and risk factors of dementia in the elderly population in a low socio-economic region of Izmir, Turkey. Arch Gerontol Geriatr. 2006;43(1):93-100.
  • 13. Şentürk İA, Başar HM, Soykök GU, et al. Prevalence of Dementia and Mild Cognitive Impairment in a Rural Area of Sivas, Turkey. Cureus. 2021;13(2):e13069.
  • 14. Güner M, Koca M, Ceylan S, et al. Prevalence and general characteristics of dementia: a nationwide population-based study of electronic health records in Türkiye. Turk J Med Sci. 2024;54(4):644-651.
  • 15. Harmanci H, Emre M, Gurvit H, et al. Risk factors for Alzheimer disease: a population-based case-control study in Istanbul, Turkey. Alzheimer Dis Assoc Disord. 2003;17(3):139-145.
  • 16. Türkiye İstatistik Kurumu (TUİK). Elderly Statistics, 2024 [online]. Available at https://data.tuik.gov.tr/Bulten/ Index?p=Elderly-Statistics-2024-54079. . Accessed July 09, 2025.
  • 17. Tsoi KK, Chan JY, Hirai HW, Wong SY, Kwok TC. Cognitive Tests to Detect Dementia: A Systematic Review and Meta-analysis. JAMA Internal Medicine. 2015;175(9):1450- 1458.
  • 18. Crawford S, Whitnall L, Robertson J, Evans JJ. A systematic review of the accuracy and clinical utility of the Addenbrooke's Cognitive Examination and the Addenbrooke's Cognitive Examination-Revised in the diagnosis of dementia. Int J Geriatr Psychiatry. 2012;27(7):659-669.
  • 19. Larner AJ, Mitchell AJ. A meta-analysis of the accuracy of the Addenbrooke's Cognitive Examination (ACE) and the Addenbrooke's Cognitive Examination-Revised (ACE-R) in the detection of dementia. Int Psychogeriatr. 2014;26(4):555-563.
  • 20. Siciliano M, Raimo S, Tufano D, et al. The Addenbrooke's Cognitive Examination Revised (ACE-R) and its sub-scores: normative values in an Italian population sample. Neurol Sci. 2016;37(3):385-392.
  • 21. Mihci E, Gurvit H, Bilgic B, et al. Validation of the Turkish version of the Addenbrooke’s Cognitive Examination in Turkey. Alzheimer’s & Dementia 2011;7:S162.
  • 22. Durmaz B, Soysal P, Ellidokuz H, et al. Validity and reliability of geriatric depression scale-15 (short form) in Turkish older adults. North Clin Istanb. 2018;5(3):216-220.
  • 23. Keskinoglu P, Ucku R, Yener G, et al. Reliability and validity of revised Turkish version of Mini Mental State Examination (rMMSE-T) in community-dwelling educated and uneducated elderly. Int J Geriatr Psychiatry. 2009;24(11):1242-1250.
  • 24. Türkiye Cumhuriyeti Resmi Gazetesi. Asgari Ücret Tespit Komisyonu Kararı. [online] Available at https://www. resmigazete.gov.tr/eskiler/2018/12/20181227-10.pdf . Accessed March 31, 2023.
  • 25. Beckert M, Loureiro F, Menta C, et al. Performance of low-educated elders with depression on Addenbrooke's Cognitive Examination-Revised (ace-r) test. Dement Neuropsycho. 2016;10(1):19-25.
  • 26. Mioshi E, Dawson K, Mitchell J, et al. The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening. Int J Geriatr Psychiatry. 2006;21(11):1078-1085.
  • 27. Orgeta V, Mukadam N, Sommerlad A, et al. The Lancet Commission on Dementia Prevention, Intervention, and Care: a call for action. Ir J Psychol Med. 2019;36(2):85-88.
  • 28. Taser S, Kutlu R, Karaoglu N. Effects of nutrition, depression symptoms and demographic characteristics on dementia in the elderly population. Marmara Medical Journal 2021;34(2):132-139.
  • 29. Alzheimer's Association. 2016 Alzheimer's disease facts and figures. Alzheimers Dement. 2016;12(4):459-509.
  • 30. Almeida OP, Flicker L. Association between hormone replacement therapy and dementia: is it time to forget?. Int Psychogeriatr. 2005;17(2):155-164.
  • 31. Langer RD, Hodis HN, Lobo RA, et al. Hormone replacement therapy - where are we now?. Climacteric. 2021;24(1):3-10.

Cognitive screening of elderly population: results from four primary healthcare centres in İstanbul, Türkiye

Year 2025, Volume: 23 Issue: 2, 175 - 186, 09.08.2025

Abstract

Objective: Our study aimed to perform cognitive screening in primary healthcare centers and examine the prevalence and
associated factors of possible cognitive impairment for İstanbul, Türkiye.
Methods: A total of 200 people (male =105, female =95) aged 65 years and older from four primary healthcare centres in
Istanbul were randomly selected and enrolled in the study. The study population was screened using a socio-demographic
survey, a validated Turkish version of the Addenbrooke’s Cognitive Examination (ACE-R) and Geriatric Depression
scale. Multilinear regression analysis was used to identify associated factors that contribute lower scores of ACE-R test.
Differences were considered statistically significant at p<0.05.
Results: Possible cognitive impairment prevalence was found 12.5% (n=25) in the study population, with females having
the higher proportion (n=20, 21.1% versus n=5, 4.8%, p<0.001). Based on multilinear regression model, high ACE-R
test scores correlated positively with more education in years (β=.462, p<0.001), negatively with living alone (β=-.286,
p=0.005), and low-income status (β=-.217, p=0.008) for male population. On the other hand, having more education in
years (β=.645, p<0.001) was the only positively correlated factor for high ACE-R test scores in the model for the female
population.
Conclusion: The study represents the most updated epidemiological information about cognitive screening at primary
heathcare level in İstanbul, Türkiye. More research is needed about cognitive decline at primary healthcare level to raise
awareness among the community.

Ethical Statement

All permissions for the study were obtained from the Yeditepe University Ethical Committee (ethics approval no: 953) and Provincial Directorate of Health in İstanbul. Informed consent forms were signed by all the study participants before data collection, and in case of the participants were unable to give the consent, written approval was sought from the legally authorized representatives who accompanied the participants in the primary healthcare centres.

Supporting Institution

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Project Number

N/A

Thanks

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References

  • 1. Hugo J, Ganguli M. Dementia and cognitive impairment: epidemiology, diagnosis, and treatment. Clin Geriatr Med. 2014;30(3):421-442.
  • 2. Gale SA, Acar D, Daffner KR. Dementia. The American Journal of Medicine. 2018;131(10):1161-1169.
  • 3. WHO. Dementia. Geneva: WHO [online]. Available at https://www.who.int/news-room/fact-sheets/detail/ dementia on 31 March 2023. Accessed March 31, 2023.
  • 4. Livingston G, Sommerlad A, Orgeta V, et al. Dementia prevention, intervention, and care. Lancet. 2017;390(10113):2673-2734.
  • 5. Livingston G, Huntley J, Sommerlad A, et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission [published correction appears in Lancet. 2023 Sep 30;402(10408):1132]. Lancet. 2020;396(10248):413- 446.
  • 6. Sachdev PS, Blacker D, Blazer DG, et al. Classifying neurocognitive disorders: the DSM-5 approach. Nat Rev Neurol. 2014;10(11):634-642.
  • 7. Tampi RR, Jeste DV. Dementia Is More Than Memory Loss: Neuropsychiatric Symptoms of Dementia and Their Nonpharmacological and Pharmacological Management. Am J Psychiatry. 2022;179(8):528-543.
  • 8. GBD 2019 Dementia Forecasting Collaborators. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health. 2022;7(2):e105-e125.
  • 9. Türkiye İstatistik Kurumu (TUİK). Elderly Statistics, 2024 [online]. Available at https://data.tuik.gov.tr/Bulten/ Index?p=Elderly-Statistics-2024-54079. Accessed July 09, 2025.
  • 10. Gurvit H, Emre M, Tinaz S, et al. The prevalence of dementia in an urban Turkish population. Am J Alzheimers Dis Other Demen. 2008;23(1):67-76.
  • 11. Arslantaş D, Ozbabalik D, Metintaş S, et al. Prevalence of dementia and associated risk factors in Middle Anatolia, Turkey. J Clin Neurosci. 2009;16(11):1455-1459.
  • 12. Keskinoglu P, Giray H, Picakciefe M, Bilgic N, Ucku R. The prevalence and risk factors of dementia in the elderly population in a low socio-economic region of Izmir, Turkey. Arch Gerontol Geriatr. 2006;43(1):93-100.
  • 13. Şentürk İA, Başar HM, Soykök GU, et al. Prevalence of Dementia and Mild Cognitive Impairment in a Rural Area of Sivas, Turkey. Cureus. 2021;13(2):e13069.
  • 14. Güner M, Koca M, Ceylan S, et al. Prevalence and general characteristics of dementia: a nationwide population-based study of electronic health records in Türkiye. Turk J Med Sci. 2024;54(4):644-651.
  • 15. Harmanci H, Emre M, Gurvit H, et al. Risk factors for Alzheimer disease: a population-based case-control study in Istanbul, Turkey. Alzheimer Dis Assoc Disord. 2003;17(3):139-145.
  • 16. Türkiye İstatistik Kurumu (TUİK). Elderly Statistics, 2024 [online]. Available at https://data.tuik.gov.tr/Bulten/ Index?p=Elderly-Statistics-2024-54079. . Accessed July 09, 2025.
  • 17. Tsoi KK, Chan JY, Hirai HW, Wong SY, Kwok TC. Cognitive Tests to Detect Dementia: A Systematic Review and Meta-analysis. JAMA Internal Medicine. 2015;175(9):1450- 1458.
  • 18. Crawford S, Whitnall L, Robertson J, Evans JJ. A systematic review of the accuracy and clinical utility of the Addenbrooke's Cognitive Examination and the Addenbrooke's Cognitive Examination-Revised in the diagnosis of dementia. Int J Geriatr Psychiatry. 2012;27(7):659-669.
  • 19. Larner AJ, Mitchell AJ. A meta-analysis of the accuracy of the Addenbrooke's Cognitive Examination (ACE) and the Addenbrooke's Cognitive Examination-Revised (ACE-R) in the detection of dementia. Int Psychogeriatr. 2014;26(4):555-563.
  • 20. Siciliano M, Raimo S, Tufano D, et al. The Addenbrooke's Cognitive Examination Revised (ACE-R) and its sub-scores: normative values in an Italian population sample. Neurol Sci. 2016;37(3):385-392.
  • 21. Mihci E, Gurvit H, Bilgic B, et al. Validation of the Turkish version of the Addenbrooke’s Cognitive Examination in Turkey. Alzheimer’s & Dementia 2011;7:S162.
  • 22. Durmaz B, Soysal P, Ellidokuz H, et al. Validity and reliability of geriatric depression scale-15 (short form) in Turkish older adults. North Clin Istanb. 2018;5(3):216-220.
  • 23. Keskinoglu P, Ucku R, Yener G, et al. Reliability and validity of revised Turkish version of Mini Mental State Examination (rMMSE-T) in community-dwelling educated and uneducated elderly. Int J Geriatr Psychiatry. 2009;24(11):1242-1250.
  • 24. Türkiye Cumhuriyeti Resmi Gazetesi. Asgari Ücret Tespit Komisyonu Kararı. [online] Available at https://www. resmigazete.gov.tr/eskiler/2018/12/20181227-10.pdf . Accessed March 31, 2023.
  • 25. Beckert M, Loureiro F, Menta C, et al. Performance of low-educated elders with depression on Addenbrooke's Cognitive Examination-Revised (ace-r) test. Dement Neuropsycho. 2016;10(1):19-25.
  • 26. Mioshi E, Dawson K, Mitchell J, et al. The Addenbrooke's Cognitive Examination Revised (ACE-R): a brief cognitive test battery for dementia screening. Int J Geriatr Psychiatry. 2006;21(11):1078-1085.
  • 27. Orgeta V, Mukadam N, Sommerlad A, et al. The Lancet Commission on Dementia Prevention, Intervention, and Care: a call for action. Ir J Psychol Med. 2019;36(2):85-88.
  • 28. Taser S, Kutlu R, Karaoglu N. Effects of nutrition, depression symptoms and demographic characteristics on dementia in the elderly population. Marmara Medical Journal 2021;34(2):132-139.
  • 29. Alzheimer's Association. 2016 Alzheimer's disease facts and figures. Alzheimers Dement. 2016;12(4):459-509.
  • 30. Almeida OP, Flicker L. Association between hormone replacement therapy and dementia: is it time to forget?. Int Psychogeriatr. 2005;17(2):155-164.
  • 31. Langer RD, Hodis HN, Lobo RA, et al. Hormone replacement therapy - where are we now?. Climacteric. 2021;24(1):3-10.
There are 31 citations in total.

Details

Primary Language English
Subjects Preventative Health Care
Journal Section Original Research
Authors

Tuba Yavuz 0009-0001-3693-8784

Hale Arık Taşyıkan 0000-0003-4298-4952

Project Number N/A
Early Pub Date August 6, 2025
Publication Date August 9, 2025
Submission Date February 17, 2025
Acceptance Date July 14, 2025
Published in Issue Year 2025 Volume: 23 Issue: 2

Cite

APA Yavuz, T., & Arık Taşyıkan, H. (2025). Cognitive screening of elderly population: results from four primary healthcare centres in İstanbul, Türkiye. Turkish Journal of Public Health, 23(2), 175-186. https://doi.org/10.20518/tjph.1641031
AMA Yavuz T, Arık Taşyıkan H. Cognitive screening of elderly population: results from four primary healthcare centres in İstanbul, Türkiye. TJPH. August 2025;23(2):175-186. doi:10.20518/tjph.1641031
Chicago Yavuz, Tuba, and Hale Arık Taşyıkan. “Cognitive Screening of Elderly Population: Results from Four Primary Healthcare Centres in İstanbul, Türkiye”. Turkish Journal of Public Health 23, no. 2 (August 2025): 175-86. https://doi.org/10.20518/tjph.1641031.
EndNote Yavuz T, Arık Taşyıkan H (August 1, 2025) Cognitive screening of elderly population: results from four primary healthcare centres in İstanbul, Türkiye. Turkish Journal of Public Health 23 2 175–186.
IEEE T. Yavuz and H. Arık Taşyıkan, “Cognitive screening of elderly population: results from four primary healthcare centres in İstanbul, Türkiye”, TJPH, vol. 23, no. 2, pp. 175–186, 2025, doi: 10.20518/tjph.1641031.
ISNAD Yavuz, Tuba - Arık Taşyıkan, Hale. “Cognitive Screening of Elderly Population: Results from Four Primary Healthcare Centres in İstanbul, Türkiye”. Turkish Journal of Public Health 23/2 (August2025), 175-186. https://doi.org/10.20518/tjph.1641031.
JAMA Yavuz T, Arık Taşyıkan H. Cognitive screening of elderly population: results from four primary healthcare centres in İstanbul, Türkiye. TJPH. 2025;23:175–186.
MLA Yavuz, Tuba and Hale Arık Taşyıkan. “Cognitive Screening of Elderly Population: Results from Four Primary Healthcare Centres in İstanbul, Türkiye”. Turkish Journal of Public Health, vol. 23, no. 2, 2025, pp. 175-86, doi:10.20518/tjph.1641031.
Vancouver Yavuz T, Arık Taşyıkan H. Cognitive screening of elderly population: results from four primary healthcare centres in İstanbul, Türkiye. TJPH. 2025;23(2):175-86.

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