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Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats
Abstract
The bitter almond has been used for a long time by diabetes patients due to some important anti-diabetic effects.
In this study, we aimed to determine protective effects of bitter almond extract on the lipid-soluble vitamins,
cholesterol, glutathione (GSH), total protein, malondialdehyde (MDA), fatty acid levels of liver and kidney
tissues of streptozotocin-induced diabetic rats. According to our findings, in kidney tissue, GSH and total protein
were decreased in the Diabetes (D) and Diabetes + Bitter Almond (D+A) groups. Again MDA was increased in
the D group, but not changed in the D+A group. Our results indicated that bitter almond extract might have a
positively effect on postprandial blood glucose levels, as well as, on the GSH and MDA levels in the kidney
tissue. The decrease of postprandial glucose level and these positive results can be attributed to bitter almond
extract in the kidney tissue. The bitter almond and streptozotocin (STZ) administrations affected amount of some
important fatty acids in the liver and kidney tissues, which substrates in fatty acid metabolism on duty enzymes.
Keywords
Details
Primary Language
English
Subjects
-
Journal Section
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Publication Date
March 1, 2015
Submission Date
March 1, 2015
Acceptance Date
-
Published in Issue
Year 2015 Volume: 10 Number: 1
APA
Demır, E., Keser, S., & Yılmaz, Ö. (2015). Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats. Turkish Journal of Science and Technology, 10(1), 31-42. https://izlik.org/JA99NF46ZJ
AMA
1.Demır E, Keser S, Yılmaz Ö. Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats. TJST. 2015;10(1):31-42. https://izlik.org/JA99NF46ZJ
Chicago
Demır, E., S. Keser, and Ö. Yılmaz. 2015. “Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats”. Turkish Journal of Science and Technology 10 (1): 31-42. https://izlik.org/JA99NF46ZJ.
EndNote
Demır E, Keser S, Yılmaz Ö (March 1, 2015) Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats. Turkish Journal of Science and Technology 10 1 31–42.
IEEE
[1]E. Demır, S. Keser, and Ö. Yılmaz, “Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats”, TJST, vol. 10, no. 1, pp. 31–42, Mar. 2015, [Online]. Available: https://izlik.org/JA99NF46ZJ
ISNAD
Demır, E. - Keser, S. - Yılmaz, Ö. “Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats”. Turkish Journal of Science and Technology 10/1 (March 1, 2015): 31-42. https://izlik.org/JA99NF46ZJ.
JAMA
1.Demır E, Keser S, Yılmaz Ö. Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats. TJST. 2015;10:31–42.
MLA
Demır, E., et al. “Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats”. Turkish Journal of Science and Technology, vol. 10, no. 1, Mar. 2015, pp. 31-42, https://izlik.org/JA99NF46ZJ.
Vancouver
1.E. Demır, S. Keser, Ö. Yılmaz. Protective Effects of Bitter Almond Kernel Extract on Liver and Kidney Tissues in Streptozotocin-Induced Diabetic Rats. TJST [Internet]. 2015 Mar. 1;10(1):31-42. Available from: https://izlik.org/JA99NF46ZJ