Determination of the effects of glucomannan supplementation into probiotic & enzyme combination on performance, some blood parameters and oxidative stress index in broilers

Objective: This trial investigated the effects of adding plant-derived glucomannan to diets containing a probiotic and enzyme complex (PEx) on the performance and certain blood and oxidative stress parameters in broilers. Materials and Methods: A total of 150-day-old male broiler chicks were used in the study, and three main groups were formed (one control (C), two experimental (named PE and PEG) groups). Two TMR feed formulations were prepared for the broiler starter and grower periods. The complete diets were administered to the C group without any additives, to the PE group with 0.1% PEx added, and to the PEG group with both 0.1% PEx and additional plant glucomannan (Konjac gum) included. Results: According to the statistical data obtained at the end of the trial, it was determined that there were significant differences between the performance parameters BW, BWG, FI, and carcass weight values of the groups (P<0.05). These values were higher in the PEG group compared to the other two groups. However, it was observed that the FCR, EPEF, carcass yield and data for heart, liver, pancreas, spleen and gizzard organs of the groups were similar between the groups (P>0.05), but a trend towards change was observed in the data for the bursa of Fabricius, and it was found to be higher in the PE and PEG groups compared to the control. There were statistically significant differences between the groups in globulin, albumin and HDL cholesterol levels among the biochemical parameters (P<0.05). Globulin and HDL cholesterol levels were higher in the PE and PEG groups fed with supplemental diets, while albumin levels were lower. However, there were no significant differences between the groups in other biochemical parameters and oxidative stress (OS) indicators (TAS, TOS, and OS index) (P>0.05). Conclusion: It is thought that the combined use of PEx and glucomannan supplements at 0.1% levels in the diet produces notably positive effects, particularly on live performance parameters in broilers, and that these supplements have the potential for synergistic interaction. Additionally, it appears to contribute positively to organism health, particularly through its effects on increasing serum HDL cholesterol levels among biochemical parameters. However, more targeted studies are necessary to assess both the positive and potential negative effects on the immune system.