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Mastektomi Sonrası Yara İyileşmesinde Kan Transfüzyonunun Rolü Var mı?

Year 2009, Volume: 3 Issue: 3, 141 - 144, 11.11.2009

Abstract

Çalışmamız perioperatif kan transfüzyonu yapılmasının; postoperatif yara iyileşmesinde rolü olup olmadığını incelemek amacı ile düzenlendi. Meme kanseri dolayısıyla modifiye radikal mastektomi ve Level 1-2-3 aksiller lenf nodu disseksiyonu yapılmış 126 hastada kan transfüzyonu ve yara iyileşmesi arasındaki muhtemel ilişki flep iskemi-nekrozu, yara yeri enfeksiyonu, total drenaj
miktarı ve total drenaj süresi parametreleriyle incelendi. Yara yeri enfeksiyonu insizyon hattında eritem-ödem-akıntı-pürülan dren getirisi göz önüne alınarak değerlendirildi. Flep iskemi ve nekrozu belirleme ve ölçmede saydam kağıt metodu kullanılmıştı. Hastalar kan transfüzyonu yapılmış (Grup 1: 72 hasta) ve kan transfüzyonu yapılmamış (Grup 2: 54 hasta) olarak 2 gruba ayrıldı. Bu iki
grup hasta dosyaları günlük takip kayıtları kullanılarak retrospektif olarak incelendi. Transfüzyon yapılan ve yapılmayan gruplar arasında yukarıdaki parametreler açısından anlamlı fark bulunmadı. Metabolik olarak kesin endikasyonu bulunan şartlar dışında kan transfüzyonu açısından rölatif endikasyonlar ortaya çıktığında, yara iyileşmesine katkıda bulunmayabileceği de göz önüne alınarak kan transfüzyonu yapılması açısından oldukça ihtiyatlı davranmanın hastalığın prognozuna olumlu katkı sağlayabileceği görüşündeyiz.

References

  • 1. Yang MT, Rong TH, Huang ZF et al, Clinical analysis of resectable breast cancer: a report of 6 263 cases. Ai Zheng 2005;24(3):327-31.
  • 2. Leinung S, Schönfelder M, Winzer KJ et al, Wound infection and infection-promoting factors in breast cancer surgery -- a prospective multicenter study on quality control. Zentralbl Chir 2005;130(1):16-20.
  • 3. Vitug AF, Newman LA, Complications in breast surgery. Surg Clin North Am 2007;87(2):431-51.
  • 4. Kompatscher P, von Planta A, Spicher I et al. Comparison of the incidence and predicted risk of early surgical site infections after breast reduction. Aesthetic Plast Surg 2003;27(4): 308-14.
  • 5. Barber GR, Miransky J, Brown AE et al. Direct observations of surgical wound infections at a comprehensive cancer center. Arch Surg 1995;130(10):1042-7.
  • 6. Sørensen LT, Hørby J, Friis E, Pilsgaard B, Jørgensen T. Smoking as a risk factor for wound healing and infection in breast cancer surgery. Eur J Surg Oncol 2003;29(5):482.
  • 7. Gamboa-Bobadilla GM, Killingsworth C. Large-volume reduction mammaplasty: the effect of body mass index on postoperative complications. Ann Plast Surg 2007;58(3):246-9.
  • 8. Nicolas P, Yazdan Y, Marie-Pierre C,et al. Prevention of surgical site infection after breast cancer surgery by targeted prophylaxis antibiotic in patients at high risk of surgical site infection. J Surg Oncol 2007;96(2):124-9.
  • 9. Lefebvre D, Penel N, Deberles MF, Fournier C. Incidence and surgical wound infection risk factors in breast cancer surgery. Presse Med 2000;29(35):1927-32.
  • 10. Denison U, Baumann J, Peters-Engl C,et al. Incidence of anaemia in breast cancer patients receiving adjuvant chemotherapy. Breast Cancer Res Treat 2003;79(3):347-53.
  • 11. Beale E, Zhu J, Chan L, Shulman I, Harwood R, Demetriades D. Blood transfusion in critically injured patients: a prospective study. Injury 2006;37(5):455-65.
  • 12. Levi N,Sandberg T. Blood transfusion and postoperative wound infection in intacapsuler femoral neck fractures. Bull Hosp Jt Dis 1998;57(2):69-73.
  • 13. Herman K, Kołodziejski L. Blood transfusion and survival after surgery for stage I and II breast cancer. Neoplasma 1993;40(2):117-25.
  • 14. Tartter PI, Burrows L, Papatestas AE, Lesnick G, Aufses AH Jr. Perioperative blood transfusion has prognostic significance for breast cancer. Surgery 1985;97(2):225-30.
  • 15. Pysz M. Blood transfusions in breast cancer patients undergoing mastectomy: possible importance of timing. J Surg Oncol 2000;75(4): 258-63.
  • 16. Shiba H, Ishida Y, Wakiyama S, et al. Negative impact of blood transfusion on recurrence and prognosis of hepatocellular carcinoma after hepatic resection.J Gastrointest Surg 2009;13(9):1636-42.
  • 17. Dionigi G, Boni L, Rovera F, et al. Effect of perioperative blood transfusion on clinical outcomes in hepatic surgery for cancer. World J Gastroenterol 2009;15(32):3976-83.
  • 18. Gerber B, Arndt M, Wesselburg C, Krause A. Responsibility for patient education and incidence of homologous blood transfusions in unilateral breast cancer operations. Geburtshilfe rauenheilkd 1995;55(10):572-6.
  • 19. Arndt M, Gerber B, Wesselburg C, Krause A, Benad G. Transfusion incidence and indications for homologous blood sparing measures in single stage breast carcinoma operations. Anaesthesiol Reanim 1995;20(6):153-6.
Year 2009, Volume: 3 Issue: 3, 141 - 144, 11.11.2009

Abstract

References

  • 1. Yang MT, Rong TH, Huang ZF et al, Clinical analysis of resectable breast cancer: a report of 6 263 cases. Ai Zheng 2005;24(3):327-31.
  • 2. Leinung S, Schönfelder M, Winzer KJ et al, Wound infection and infection-promoting factors in breast cancer surgery -- a prospective multicenter study on quality control. Zentralbl Chir 2005;130(1):16-20.
  • 3. Vitug AF, Newman LA, Complications in breast surgery. Surg Clin North Am 2007;87(2):431-51.
  • 4. Kompatscher P, von Planta A, Spicher I et al. Comparison of the incidence and predicted risk of early surgical site infections after breast reduction. Aesthetic Plast Surg 2003;27(4): 308-14.
  • 5. Barber GR, Miransky J, Brown AE et al. Direct observations of surgical wound infections at a comprehensive cancer center. Arch Surg 1995;130(10):1042-7.
  • 6. Sørensen LT, Hørby J, Friis E, Pilsgaard B, Jørgensen T. Smoking as a risk factor for wound healing and infection in breast cancer surgery. Eur J Surg Oncol 2003;29(5):482.
  • 7. Gamboa-Bobadilla GM, Killingsworth C. Large-volume reduction mammaplasty: the effect of body mass index on postoperative complications. Ann Plast Surg 2007;58(3):246-9.
  • 8. Nicolas P, Yazdan Y, Marie-Pierre C,et al. Prevention of surgical site infection after breast cancer surgery by targeted prophylaxis antibiotic in patients at high risk of surgical site infection. J Surg Oncol 2007;96(2):124-9.
  • 9. Lefebvre D, Penel N, Deberles MF, Fournier C. Incidence and surgical wound infection risk factors in breast cancer surgery. Presse Med 2000;29(35):1927-32.
  • 10. Denison U, Baumann J, Peters-Engl C,et al. Incidence of anaemia in breast cancer patients receiving adjuvant chemotherapy. Breast Cancer Res Treat 2003;79(3):347-53.
  • 11. Beale E, Zhu J, Chan L, Shulman I, Harwood R, Demetriades D. Blood transfusion in critically injured patients: a prospective study. Injury 2006;37(5):455-65.
  • 12. Levi N,Sandberg T. Blood transfusion and postoperative wound infection in intacapsuler femoral neck fractures. Bull Hosp Jt Dis 1998;57(2):69-73.
  • 13. Herman K, Kołodziejski L. Blood transfusion and survival after surgery for stage I and II breast cancer. Neoplasma 1993;40(2):117-25.
  • 14. Tartter PI, Burrows L, Papatestas AE, Lesnick G, Aufses AH Jr. Perioperative blood transfusion has prognostic significance for breast cancer. Surgery 1985;97(2):225-30.
  • 15. Pysz M. Blood transfusions in breast cancer patients undergoing mastectomy: possible importance of timing. J Surg Oncol 2000;75(4): 258-63.
  • 16. Shiba H, Ishida Y, Wakiyama S, et al. Negative impact of blood transfusion on recurrence and prognosis of hepatocellular carcinoma after hepatic resection.J Gastrointest Surg 2009;13(9):1636-42.
  • 17. Dionigi G, Boni L, Rovera F, et al. Effect of perioperative blood transfusion on clinical outcomes in hepatic surgery for cancer. World J Gastroenterol 2009;15(32):3976-83.
  • 18. Gerber B, Arndt M, Wesselburg C, Krause A. Responsibility for patient education and incidence of homologous blood transfusions in unilateral breast cancer operations. Geburtshilfe rauenheilkd 1995;55(10):572-6.
  • 19. Arndt M, Gerber B, Wesselburg C, Krause A, Benad G. Transfusion incidence and indications for homologous blood sparing measures in single stage breast carcinoma operations. Anaesthesiol Reanim 1995;20(6):153-6.
There are 19 citations in total.

Details

Primary Language Turkish
Subjects General Surgery
Journal Section Research Article
Authors

Ahmet Ay This is me

Publication Date November 11, 2009
Published in Issue Year 2009 Volume: 3 Issue: 3

Cite

APA Ay, A. (2009). Mastektomi Sonrası Yara İyileşmesinde Kan Transfüzyonunun Rolü Var mı?. Türk Tıp Dergisi, 3(3), 141-144.

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