AN EVALUATION OF ENDOSCOPIC FINDINGS AND ENDOSCOPIC BIOPSY RESULTS OF THE PATIENTS WITH CHRONIC DIARRHEA

Year 2010, Volume: 4 Issue: 3, 115 - 119, 22.11.2010

Reyhan Ersoy

Abstract

In our study, we aimed to evaluate the endoscopic imaging findings of upper gastrointestinal tract to determine the etiology of chronic diarrhea and the histopathological results of biopsy materials conducted on the duodenal mucosa.

Forty five patients of our clinic who underwent upper gastrointestinal tract endoscopy due to chronic diarrhea were included in the study. The data about laboratory parameters, endoscopic examination and pathology reports were obtained from the electronic databases of our hospital, retrospectively.
Twenty five (55.6 %) of the patients were male and twenty of them were female; as the mean age of all was 37,5 ± 16,1 years (18-68). Histopathological examination demonstrated duodenitis (varying from nonspecific to chronic) in 34 (75.6 %) patients and Giardiazis in 8 (17.8 %) patients. There were no abnormal histopathologic findings in 3 (6.7 %) patients.

Through such regions like our country parasitic infections are so common, it would be useful to perform upper gastrointestinal tract endoscopy to patients who have chronic diarrhea even if no parasites were detected by direct microscopy of the faeces and carry out histopathological examination although the duodenum seems to be normal endoscopically in order to identify G. Lamblia infections.

Keywords

Chronic diarrhea, endoscopy, histopathology

KRONİK İSHAL NEDENİYLE BAŞVURAN HASTALARDA ENDOSKOPİ VE ENDOSKOPİK BİYOPSİ SONUÇLARININ DEĞERLENDİRİLMESİ

Abstract

Çalışmamızda kronik ishal etyolojisini belirlemede üst gastrointestinal sistemin endoskopik görüntüleme bulgularını ve duodenum mukozasından alınan biyopsi materyallerinin histopatolojik sonuçlarını değerlendirmeyi amaçladık.

Kliniğimizde kronik ishal nedeni ile üst gastrointestinal sistem endoskopisi yapılan 45 hasta çalışmaya alındı. Çalışmaya alınan tüm hastaların laboratuar parametreleri, endoskopik inceleme ve patoloji sonuçları hastane elektronik veritabanından geriye dönük tarama ile elde edildi.

Çalışmaya alınan 45 hastanın 25’i (%55,6) erkek ve 20’si (%44,4) kadın olup yaş ortalaması 37,5 ±16,1 yıl (18-68) idi. Duodenal biyopsilerin histopatolojik değerlendirilmesinde 34 hastada (%75,6) duodenit (non spesifik duodenitten kronik duodenite kadar değişen) ve 8 hastada (% 17,8) Giardia tespit edildi. Üç hastada (%6,7) normal histopatolojik bulgular saptandı.
Ülkemiz gibi paraziter enfeksiyonların sık rastlanıldığı bölgelerde gaita direk incelemesinde parazit saptanamayan kronik ishalli hastalara üst gastrointestinal sistem endoskopisi yapılması, duodenumun endoskopik görünümü normal olsa bile histopatolojik değerlendirmesi G. Lamblia enfeksiyonunun saptanmasında yararlı olacaktır.

Dr. Atilla AYBAR
Dr. Tuncer KILIÇ
Dr. Ünal KILIÇ
Dr. Aydan KILIÇARSLAN
Dr. Fatma Ebru AKIN
Dr. Reyhan ERSOY
Dr. Osman ERSOY
Dr. Bekir ÇAKIR

Keywords

Kronik ishal, endoskopi, histopatoloji

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