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Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats

Year 2013, Volume: 3 Issue: 3, 164 - 170, 23.07.2016

Abstract

The potency of aqueous white grubs extract was assessed in the cure of carbon tetrachloride (CCl4) – induced lipoperoxidation in rats. The three different dosages were administered (1g/kg, 2g/kg and 8g/kg) daily to different groups of rats for up to 9 days after induced with lipoperoxidation using CCl4 at a dose of 120mg/kg. the serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) activities as well as levels of serum malondialdehyde (MDA), total protein (TP) and albumin (ALB) of the rats after 9 days of white grubs administration were found to be similar to those of control rats (not CCl4 – treated). This shows possible curative effects of the white grubs extract, which was found to be depend on both the dose administered and the duration of treatment

References

  • Ahmed, I., Agil, F. and Owais M. (2006). Modern Phytomedicine. Turning Medicinal Plant into Drugs. John Wiley and Sons, West – Sussex England. Pp. 2-24.
  • Aiken, G., McKnight, D. and Wershaw, R. (1985). Humic Substances in Soil, Sediment, and Water. Vol. 1.Jon Wiley: New York.
  • Alhassan, A. J., Sule, M. S., Hassan, J. A., Baba, B. A. and Aliyu, M. D. (2009a).
  • Proximate and elemental composition of white grubs. Bayero Journal of Pure and Applied Sciences 2(2): 188 – 190.
  • Alhassan, A. J., Sule, M. S., Hassan, J. A., Baba, B. A. and Aliyu, M. D. (2009b).
  • Ideal Hepathotoxicity Model in Rats using Carbon tetrachloride (CCl4). Bayero Journal of Pure and Applied Sciences 2(2): 185 – 187.
  • Alhassan, A. J. (2010). Medicinal and Toxicological Effect of Aqueous of White Grubs and Characterization of its Protein and Lipid Contents. Unpublished manuscript, PhD Thesis Department of Biochemistry, Bayero University, Kano.
  • Burtis C. A., Ashwood E.R. and Boder B. G., (2001). Tietz Fundamentals of Clinical
Year 2013, Volume: 3 Issue: 3, 164 - 170, 23.07.2016

Abstract

References

  • Ahmed, I., Agil, F. and Owais M. (2006). Modern Phytomedicine. Turning Medicinal Plant into Drugs. John Wiley and Sons, West – Sussex England. Pp. 2-24.
  • Aiken, G., McKnight, D. and Wershaw, R. (1985). Humic Substances in Soil, Sediment, and Water. Vol. 1.Jon Wiley: New York.
  • Alhassan, A. J., Sule, M. S., Hassan, J. A., Baba, B. A. and Aliyu, M. D. (2009a).
  • Proximate and elemental composition of white grubs. Bayero Journal of Pure and Applied Sciences 2(2): 188 – 190.
  • Alhassan, A. J., Sule, M. S., Hassan, J. A., Baba, B. A. and Aliyu, M. D. (2009b).
  • Ideal Hepathotoxicity Model in Rats using Carbon tetrachloride (CCl4). Bayero Journal of Pure and Applied Sciences 2(2): 185 – 187.
  • Alhassan, A. J. (2010). Medicinal and Toxicological Effect of Aqueous of White Grubs and Characterization of its Protein and Lipid Contents. Unpublished manuscript, PhD Thesis Department of Biochemistry, Bayero University, Kano.
  • Burtis C. A., Ashwood E.R. and Boder B. G., (2001). Tietz Fundamentals of Clinical
There are 8 citations in total.

Details

Other ID JA56MA64EG
Journal Section Articles
Authors

M. S. Sule This is me

A. J. Alhassan This is me

Y. Abdulmumuni This is me

Publication Date July 23, 2016
Published in Issue Year 2013 Volume: 3 Issue: 3

Cite

APA Sule, M. S., Alhassan, A. J., & Abdulmumuni, Y. (2016). Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats. TOJSAT, 3(3), 164-170.
AMA Sule MS, Alhassan AJ, Abdulmumuni Y. Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats. TOJSAT. July 2016;3(3):164-170.
Chicago Sule, M. S., A. J. Alhassan, and Y. Abdulmumuni. “Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats”. TOJSAT 3, no. 3 (July 2016): 164-70.
EndNote Sule MS, Alhassan AJ, Abdulmumuni Y (July 1, 2016) Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats. TOJSAT 3 3 164–170.
IEEE M. S. Sule, A. J. Alhassan, and Y. Abdulmumuni, “Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats”, TOJSAT, vol. 3, no. 3, pp. 164–170, 2016.
ISNAD Sule, M. S. et al. “Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats”. TOJSAT 3/3 (July 2016), 164-170.
JAMA Sule MS, Alhassan AJ, Abdulmumuni Y. Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats. TOJSAT. 2016;3:164–170.
MLA Sule, M. S. et al. “Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats”. TOJSAT, vol. 3, no. 3, 2016, pp. 164-70.
Vancouver Sule MS, Alhassan AJ, Abdulmumuni Y. Potency of Aqueous White Grubs Extract Against CCl4 Induced Liver Diseases in Rats. TOJSAT. 2016;3(3):164-70.