Primary Nasopharyngeal Hodgkins Disease: A Case Report

Abstract

Primary nasopharyngeal Hodgkin's disease occurs in less than %1 of all Hodgkin's disease cases. With appropriate treatment, the prognosis for this particular type of Hodgkin's Lenfoma is favorable. Most documented cases of Hodgkin's Lenfoma are either stage 1 or 2 patients. A 53-year-old male patient presented with bilateral nasal obstruction. Endoscopic examination of the nasal cavity revealed a mass arising from the nasopharynx. After the excision histopatological study reported the case to be classic Hodgkin's Lenfoma, of a nodular sclerosis type. Bone marrow core biopsy, scanning of chest, abdomen and neck were normal. Further positron emission tomographic scan also showed no abnormalities. The patient was considered to have stage 1EA nasopharyngeal Hodgkin's Lenfoma and was treated with radiotherapy and 6 cycles of chemothreapy. We aim to present this uncommon case of Hodgkin's Lenfoma confined to the nasopharynx with a review of the literature. Key words: Hodgkin's disease; Nasopharynx; Prognosis.

Keywords

• Hodgkin's disease; Nasopharynx; Prognosis.

Primer Nazofarengeal Hodgkin Lenfoma: Olgu Sunumu

Öz

Hodgkin lenfomaların yaklaşık olarak %1'inden azını primer nazofarengeal tutulum oluşturur. Bu bölgedeki Hodgkin lenfomaların uygun tedavi ile prognozları oldukça iyidir. Bildirilen Hodgkin vakalarının birçoğu evre 1 veya 2' de saptanmıştır. Bilateral burun tıkanıklığı şikayetiyle polikliniğimize başvuran 53 yaşındaki erkek hastanın yapılan endoskopik bakısında nazofarenkste kitlesi saptandı. Hastanın eksizyon sonrası patoloji sonucu ‘klasik tip Hodgkin Lenfoma–nodüler sklerozan' şeklinde raporlandı. Kemik iliği biyopsisi, toraks, abdomen ve boyun bilgisayarlı tomografi (BT) sonuçları normal izlendi. Yapılan Pozitron Emisyon Tomografi (PET) normal sınırlardaydı. Evre 1EA olarak değerlendirilen bu hastaya ardışık radyoterapi ve 6 kür kemoterapi uygulandı. Biz de bu olgunun tanı ve tedavi sürecini literatür eşliğinde sunmayı amaçladık. Anahtar kelimeler: Hodgkin Lenfoma; Nazofarenks; Prognoz.

Anahtar Kelimeler

• Hodgkin Lenfoma; Nazofarenks; Prognoz.

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