Neurological Involvement in Behçet’s Disease

Abstract

Behçet's Disease is an episodic disorder of unknown aetiology or pathogenesis, characterized by recurrent oral and genital ulceration and panuveitis. Neurological involvement is well described in Behçet Disease, with prevalance rates of 2.2-50%. Neurological involvement most commonly is reported to manifest as brainstem or corticospinal tract syndromes, increased intracranial pressure mostly related to venous sinus thrombosis or aseptic meningitis, isolated behavioral symptoms, or isolated headache. The aim of this study was to report Neuro-Behçet Disease, describe their various characteristics and attempt to categorize the neurological presentations into characteristics clinical patterns. Key words: Behçet's Disease, Neurological involvement, Neuroimaging.

Keywords

• Behçet's Disease, Neurological involvement, Neuroimaging.

Behçet Hastalığında Nörolojik Tutulum

Öz

Behçet hastalığı, heterojen, epizodik, patojenezi ve etiyolojisi tam olarak bilinmeyen bir multisistem inflamatuar hastalıktır. Tekrarlayan oral ve genital ülserler ve panüveit ile karakterizedir. Behçet Hastalığında nörolojik etkilenme iyi tanımlanmıştır ve prevalansı %2.2 ile %50 oranında bildirilir. Nörolojik tutulum olarak sıklıkla beyinsapı veya kortikospinal yol sendromları, çoğunlukla venöz sinus trombosu veya aseptik menenjite bağlı olarak gelişen artmış kafaiçi basıncı, davranışsal bozukluklar veya izole başağrısı tanımlanmıştır. Sunulan çalışmada akut nörolojik tutulumla Nöroloji Servisi'ne başvuran Behçet hastalığı olan hastalarda, nörolojik tutulum bulguları literatür eşliğinde gözden geçirildi. Anahtar kelimeler: Behçet Hastalığı, Nörolojik tutulum, Nörogörüntüleme.

Anahtar Kelimeler

• Behçet Hastalığı, Nörolojik tutulum, Nörogörüntüleme.

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