Abstract
Aim: Our aim of this retrospective study was to evaluate the demographic, histopathologic and radiological features of thyroid cancer patients. Material and Methods: In our study 129 thyroid cancer patients were divided into two groups: group 1 (tumor size <1cm) and group 2 (tumor size >1 cm). Parameters were age, gender, preoperative thyroid function test results, findings of nodule structure, nodule echogenicity and border features, presence of microcalcification and halo and anterioposterior diameter in preoperative thyroid ultrasonography, presence of radioactive iodine therapy, postoperative thyroglobulin values, postoperative diagnosis, histological type and size of the tumor, presence of multifocality and bilaterality, presence of invasion and recurrence after therapy. Results: 27 (20.9%) of the patients were male and the remaining 102 (79.1%) patients were female. The preoperative average age was 44.8±14.4 years. There were no significant differences between two groups when compared to their age, fT3, fT4, TSH, TG, anti-TPO, anti-TG, supplementary operation, postoperative aphonia, hypocalcemia symptoms, multifocality of the tumor, bilateral tumor presence, nodule halo, anterioposterior diameter, recurrence, results of thyroid fine needle aspiration biopsy, structure and echogeneity of the nodule and pre- and postoperative diagnostic features. Most common preoperative histopathological diagnosis was suspicious malignancy (39.6%), whereas the most common postoperative diagnosis was papillary carcinoma (88.5%). Conclusion: Extensive studies will enable the approaches with a result to minimize the disease related mortality and enable the early diagnosis of thyroid cancers. Key words: Thyroid Cancer; Patients; Demography; Histopathology; Epidemiology; Ultrasonography.
References
- Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States 1973-2002. JAMA 2006;295:2164—7.
- Hayat MJ, Howlader N, Reichman ME, Edwards BK. Cancer statistics, trends, and multiple primary cancer analyses from the surveillance, epidemiology, and end results (SEER) program. Oncologist 2007;12:20—37.
- Hay ID. Papillary thyroid carcinoma. Endocrinol Metab Clin North Am 1990;19:545—76.
- Bosetti C, Kolonel L, Negri E, Ron E, Franceschi S, Dal Maso L et al. A pooled analysis of case—control studies of thyroid cancer. VI. Fish and shellfish consumption. Cancer Causes Control 2001 ;1 2375-82.
- Shattuck TM, Westra WH, Ladenson PW, Arnold A.
- Hay ID, Thompson GB, Grant CS, Bergstralh EJ, Dvorak CE, 2005;352:2406—12.
- Gorman CA et al. Papillary thyroid carcinoma managed at
- the Mayo Clinic during six decades (1940—1999): temporal
- trends in initial therapy and long—term outcome in 2444
- consecutively treated patients. World J Surg 2002;26:879-85.
- Schlumberger M, De Vathaire F, Travagli JP, Vassal G,
- Lemerle J, Parmentier C et al. Differentiated thyroid
- Zimmerman D, Hay ID, Gough IR, Goellner JR, Ryan JJ,
- Grant CS et al. Papillary thyroid carcinoma in children and
- Watson RG, Brennan MD, Goellner JR, van Heerden JA, McConahey WM, Taylor WF. Invasive Hurthle cell carcinoma ofthe thyroid: natural history and management. Mayo Clin Proc1984;59:851-5.
- Henry M K, Shlomo Melmed, Kenneth S. Polonsky, P. Reed
- Larsen,. Williams Textbook of endocrinology,. Management
- Salvador Egea MP, Echegoyen Silanes AA, Layana Echezuri
- E, Anda Apinariz E, Puras Gil A, Menendez Torre E et al.
- Hundahl SA, Fleming ID, Fremgen AM, Menck HR. A
- National Cancer Data Base report on 53.856 cases of thyroid carcinoma treated in the US, 1985—1995. Cancer 1998;83:2638—48.
Tiroid Kanserli Hastaların Demografik, Histopatolojik ve Radyolojik Özellliklerinin Değerlendirilmesi
Abstract
Amaç: Bu retrospektif çalışmada tiroid kanserli hastaların demografik, histopatolojik ve radyolojik özellikleri değerlendirildi. Gereç ve Yöntemler: Tiroid kanserli 129 hastanın alındığı çalışmada hastalar 2 gruba ayrıldı: grup 1 tümör boyutu 1 cm'den küçük olan hastalar ve grup 2 tümör boyutu bir cm'den büyük olan hastalar. Yaş, cinsiyet, preoperatif tiroid fonksiyon test sonuçları, tiroid ultrasonografisinde nodül yapısı, nodül ekosu ve kenar özelliği, mikrokalsifikasyon ve halo varlığı, anteroposterior çapı, hastanın radyoaktif iyot tedavisi alıp almadığı, postoperatif tiroglobulin değerleri, postoperatif tanı, tümörün histolojik tipi, boyutu, multifokalite ve bilateralite durumu, invazyon varlığı ve tedavi sonrası nüks varlığı değerlendirildi. Bulgular: Hastaların 27'si (%20.9) erkek ve 102'si (%79.1) kadındı. Hastaların preoperatif yaş ortalaması 44.8±14.4 yıl olarak saptandı. Her iki grup arasında yaş, fT3, fT4, TSH, TG, anti-TPO, anti-TG, tamamlayıcı operasyon, postoperatif ses kısıklığı ve hipokalsemi belirtileri, tümörün multifokal olması, tümörün bilateral yerleşimi, nodül halosu, nodül anteroposterior çapı, nüks, tiroid ince iğne aspirasyon biyopsi sonuçları, nodül yapısı ve nodül ekosu, bakımından anlamlı fark saptanmadı. En sık görülen preoperatif histopatolojik tanı şüpheli malignite (%39.6) iken, postoperatif en sık tanı papiller karsinom (%88.5) olarak rapor edildi. Sonuç: Geniş çaplı araştırmalar tiroid kanserlerinin erken tanıları ve hastalığa bağlı mortalitelerini en az düzeye indirebilecek tedavi yaklaşımlarının gelişmesine imkan sağlayacaktır. Anahtar kelimeler: Tiroid Kanseri; Hastalar; Demografi; Histopatoloji; Epidemiyoloji; Ultrasonografi.
References
- Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States 1973-2002. JAMA 2006;295:2164—7.
- Hayat MJ, Howlader N, Reichman ME, Edwards BK. Cancer statistics, trends, and multiple primary cancer analyses from the surveillance, epidemiology, and end results (SEER) program. Oncologist 2007;12:20—37.
- Hay ID. Papillary thyroid carcinoma. Endocrinol Metab Clin North Am 1990;19:545—76.
- Bosetti C, Kolonel L, Negri E, Ron E, Franceschi S, Dal Maso L et al. A pooled analysis of case—control studies of thyroid cancer. VI. Fish and shellfish consumption. Cancer Causes Control 2001 ;1 2375-82.
- Shattuck TM, Westra WH, Ladenson PW, Arnold A.
- Hay ID, Thompson GB, Grant CS, Bergstralh EJ, Dvorak CE, 2005;352:2406—12.
- Gorman CA et al. Papillary thyroid carcinoma managed at
- the Mayo Clinic during six decades (1940—1999): temporal
- trends in initial therapy and long—term outcome in 2444
- consecutively treated patients. World J Surg 2002;26:879-85.
- Schlumberger M, De Vathaire F, Travagli JP, Vassal G,
- Lemerle J, Parmentier C et al. Differentiated thyroid
- Zimmerman D, Hay ID, Gough IR, Goellner JR, Ryan JJ,
- Grant CS et al. Papillary thyroid carcinoma in children and
- Watson RG, Brennan MD, Goellner JR, van Heerden JA, McConahey WM, Taylor WF. Invasive Hurthle cell carcinoma ofthe thyroid: natural history and management. Mayo Clin Proc1984;59:851-5.
- Henry M K, Shlomo Melmed, Kenneth S. Polonsky, P. Reed
- Larsen,. Williams Textbook of endocrinology,. Management
- Salvador Egea MP, Echegoyen Silanes AA, Layana Echezuri
- E, Anda Apinariz E, Puras Gil A, Menendez Torre E et al.
- Hundahl SA, Fleming ID, Fremgen AM, Menck HR. A
- National Cancer Data Base report on 53.856 cases of thyroid carcinoma treated in the US, 1985—1995. Cancer 1998;83:2638—48.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | June 1, 2013 |
| Published in Issue | Year 2013 Volume: 20 Issue: 3 |