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Placental Mesenchymal Dysplasia Clinically Diagnosed As Partial Hydatidiform Mole: Case Report

Year 2008, Volume: 15 Issue: 3, 207 - 210, 01.06.2008

Abstract

Placental mesenchymal dysplasia is a rare placental abnormality. Placenta is found to be enlarged with cystic villi and dilated thick vascular structures. Importance of this abnormality is the clinical and morphological similarity to the partial hydatidiform mole and presentation with Beckwith- Wiedemann syndrome. Our case was diagnosed as partial hydatidiform mole in her rutin pregnancy controls. This is the 20. case in literature that had not any extra-placental abnormality. Key words: Placental mesenchymal dysplasia, Partial hydatidiform mole

References

  • Sander CM. Angiomatous malformation of placental chorionic stem vessels and pseudo-partial molar placentas: report of five cases. Pediatr Pathol 1993;13(5):621–33.
  • Hojberg KE, Aagaard J, Henriques U, Sunde L. Placental vascular malformation with mesenchymal hyperplasia and a localized chorioangioma. A rarity simulating partial mole. Pathol Res Pract 1994;190(8):808–13.
  • Chen CP, Chern SR, Wang TY, Huang ZD, Huang MC, Chuang CY. Pregnancy with concomitant chorangioma and placental vascular malformation with mesenchymal hyperplasia. Hum Reprod 1997; 12(11):2553–56.
  • Mulc AD, Stallings SP, Salafia CM. Elevated maternal serum alpha-fetoprotein, umbilical vein varix, and mesenchymal dysplasia: are they related? Prenat Diagn 2006;26(8):659–61.
  • Pham T, Steele J, Stayboldt C, Chan L, Benirschke K. Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol 2006;126(1):67–78
  • Gibson BR, Muir-Padilla J, Champeaux A, Suarez ES. Mesenchymal dysplasia of the placenta. Placenta 2004; 25(7):671–2.
  • Takayama M, Soma H, Yaguchi S, Funayama H, Fujiwara K, Irie H, Yamabe S. Abnormally large placenta associated with Beckwith-Wiedemann syndrome. Gynecol Obstet Invest 1986;22(3):165–8.
  • Cohen MC, Roper EC, Sebire NJ, Stanek J, Anumba DO. Placental mesenchymal dysplasia associated with fetal aneuploidy. Prenat Diagn 2005; 25(3):187–92.
  • Benirschke K and Kaufmann P. Pathology of theHuman Placenta; Springer Verlag. New York: RN Baergen. 2005. ISBN 0-387-22089-5

Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu

Year 2008, Volume: 15 Issue: 3, 207 - 210, 01.06.2008

Abstract

Plasental mezenkimal displazi nadir görülen bir plasenta anomalisidir. Plasenta normalden büyük olup kistik villuslar ve genişlemiş kalın duvarlı damarlar mevcuttur. Bu anomalinin önemi klinik ve patolojik olarak parsiyel mol hidatiforma benzemesi ve genellikle Beckwith- Wiedemann sendromu ile birliktelik göstermesidir. Doğum öncesi rutin takiplerinde parsiyel mol hidatiform tanısı alan plasental mezenkimal displazi olgusu, plasenta dışında anomalisi olmayan 20. vaka olması ve nadir görülmesi nedeniyle sunulmuştur. Anahtar kelimeler: Plasental mezenkimal displazi, Parsiyel hidatiform mol

References

  • Sander CM. Angiomatous malformation of placental chorionic stem vessels and pseudo-partial molar placentas: report of five cases. Pediatr Pathol 1993;13(5):621–33.
  • Hojberg KE, Aagaard J, Henriques U, Sunde L. Placental vascular malformation with mesenchymal hyperplasia and a localized chorioangioma. A rarity simulating partial mole. Pathol Res Pract 1994;190(8):808–13.
  • Chen CP, Chern SR, Wang TY, Huang ZD, Huang MC, Chuang CY. Pregnancy with concomitant chorangioma and placental vascular malformation with mesenchymal hyperplasia. Hum Reprod 1997; 12(11):2553–56.
  • Mulc AD, Stallings SP, Salafia CM. Elevated maternal serum alpha-fetoprotein, umbilical vein varix, and mesenchymal dysplasia: are they related? Prenat Diagn 2006;26(8):659–61.
  • Pham T, Steele J, Stayboldt C, Chan L, Benirschke K. Placental mesenchymal dysplasia is associated with high rates of intrauterine growth restriction and fetal demise: A report of 11 new cases and a review of the literature. Am J Clin Pathol 2006;126(1):67–78
  • Gibson BR, Muir-Padilla J, Champeaux A, Suarez ES. Mesenchymal dysplasia of the placenta. Placenta 2004; 25(7):671–2.
  • Takayama M, Soma H, Yaguchi S, Funayama H, Fujiwara K, Irie H, Yamabe S. Abnormally large placenta associated with Beckwith-Wiedemann syndrome. Gynecol Obstet Invest 1986;22(3):165–8.
  • Cohen MC, Roper EC, Sebire NJ, Stanek J, Anumba DO. Placental mesenchymal dysplasia associated with fetal aneuploidy. Prenat Diagn 2005; 25(3):187–92.
  • Benirschke K and Kaufmann P. Pathology of theHuman Placenta; Springer Verlag. New York: RN Baergen. 2005. ISBN 0-387-22089-5
There are 9 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Nuray Başsüllü This is me

İlknur Türkmen This is me

Gülben Erdem Huq This is me

Övgü Aydın This is me

Zerrin Calay This is me

Herman İşçi This is me

Publication Date June 1, 2008
Published in Issue Year 2008 Volume: 15 Issue: 3

Cite

APA Başsüllü, N., Türkmen, İ., Huq, G. E., Aydın, Ö., et al. (2008). Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu. Journal of Turgut Ozal Medical Center, 15(3), 207-210.
AMA Başsüllü N, Türkmen İ, Huq GE, Aydın Ö, Calay Z, İşçi H. Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu. J Turgut Ozal Med Cent. June 2008;15(3):207-210.
Chicago Başsüllü, Nuray, İlknur Türkmen, Gülben Erdem Huq, Övgü Aydın, Zerrin Calay, and Herman İşçi. “Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu”. Journal of Turgut Ozal Medical Center 15, no. 3 (June 2008): 207-10.
EndNote Başsüllü N, Türkmen İ, Huq GE, Aydın Ö, Calay Z, İşçi H (June 1, 2008) Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu. Journal of Turgut Ozal Medical Center 15 3 207–210.
IEEE N. Başsüllü, İ. Türkmen, G. E. Huq, Ö. Aydın, Z. Calay, and H. İşçi, “Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu”, J Turgut Ozal Med Cent, vol. 15, no. 3, pp. 207–210, 2008.
ISNAD Başsüllü, Nuray et al. “Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu”. Journal of Turgut Ozal Medical Center 15/3 (June 2008), 207-210.
JAMA Başsüllü N, Türkmen İ, Huq GE, Aydın Ö, Calay Z, İşçi H. Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu. J Turgut Ozal Med Cent. 2008;15:207–210.
MLA Başsüllü, Nuray et al. “Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu”. Journal of Turgut Ozal Medical Center, vol. 15, no. 3, 2008, pp. 207-10.
Vancouver Başsüllü N, Türkmen İ, Huq GE, Aydın Ö, Calay Z, İşçi H. Klinikte Parsiyel Mol Hidatiform Tanısı Alan Plasental Mezenkimal Displazi: Olgu Sunumu. J Turgut Ozal Med Cent. 2008;15(3):207-10.