Cystic neuroblastoma in a newborn: A case report

Year 2008, Volume: 15 Issue: 1, 39 - 41, 01.02.2008

Sema Uğuralp Ahmet Sığırcı Neşe Karadağ

Abstract

An abdominal cystic mass with a 2.5x1.8 cm diameter was diagnosed in a 28 week- gestation female fetus using antenatal ultrasonography (US). Postnatal US confirmed a cystic mass in the right adrenal region. The abdominal computed tomography revealed a hypodense, thick walled cyst which pushed the right kidney to the lower side. Intraoperatively, the mass appeared to be within the right adrenal gland, and a right adrenalectomy was performed. Histology confirmed a poorly differentiated neuroblastoma. Cystic neuroblastoma (CNB) should be considered in the differential diagnosis of suprarenal cystic masses. It can be suggested that any cystic adrenal mass with characteristic US sign (thick wall) in a neonate must be removed since there is a probability of malignancy. Key words: Neuroblastoma, Neonate, Cystic, Prenatal

Keywords

Neuroblastoma, Neonate, Cystic, Prenatal

Bir Yenidoğanda Kistik Nöroblastoma: Olgu Sunumu

Abstract

Yirmisekiz haftalık kız fetüste antenatal ultrasonografide (US) 2.5x1.8 cm çaplı abdominal kistik kitle saptandı. Postnatal yapılan US de kistik kitlenin sağ adrenal bölgede olduğu görüldü. Abdominal kompüterize tomografide hipodens, sağ böbreği aşağı iten kalın duvarlı kist mevcuttu. Ameliyatta kitlenin sağ adrenal glandda olduğu görüldü ve sağ adrenalektomi yapıldı. Histolojik olarak kitle az diferensiye nöroblastoma olarak değerlendirildi. Suprarenal kistik kitlelerin ayırıcı tanısında kistik nöroblastoma (CNB) düşünülmelidir. US de karakteristik olarak kalın duvarlı kistik kitlesi olan bir yenidoğanda kitlenin malign olabilme ihtimaline karşı çıkarılmasını öneriyoruz. Anahtar kelimeler: Nöroblastoma, Yenidoğan, Kist, Prenatal

Keywords

Nöroblastoma, Yenidoğan, Kist, Prenatal

References

• Petit T, Lagausie P, Ghoneimi A, et al. Postnatal management of cystic neuroblastoma. Eur J Pediatr Surg 2001; 11: 411-4
• Richards ML, Gundersen AE, Williams MS (1995). Cystic neuroblastoma of infancy. J Pediatr Surg 30: 1354-7.
• Sauvat F, Sarnacki S, Brisse H, et al. Outcome of suprarenal localized masses diagnosed during the perinatal period: a retrospective multicenter study. Cancer ; 94: 2474-80
• Koksal Y, Varan A, Kale G, et al. Bilateral cystic adrenal neuroblastoma with hepatic and splenic involvement in a newborn. J Pediatr Hematol Oncol 2005; 27: 1
• Giulian BB, Chang CCN, Yoss BS. Prenatal ultrasonographic diagnosis of fetal adrenal neuroblastoma. J Clin Ultrasound 1986; 14: 225-27
• Yamagiwa I, Obata K, Saito H. Prenatally detected cystic neuroblastoma. Pediatr Surg Int 1998; 13: 215-7
• Fang SB, Lee HC, Sheu JC, et al. Prenatal sonographic detection of adrenal hemorrhage confirmed by postnatal surgery. J Clin Ultrasound 1999; 27: 206-209
• Nuchtern Jed G. Perinatal neuroblastoma. Semin Pediatr Surg 2006; 15: 10-6.
• Hartman GE, Shochat SJ. Abdominal mass lesions in the newborn: diagnosis and treatment. Clin Perinatol 1989; 16: 123-35
• Japanese Society of Pediatric Surgeons’ Malignant Tumor Committee. The total amount of registered cases with pediatric surgical malignant tumor in 1987. J Jpn Soc Pediatr Surg 1989; 25: 124-7. Correspondence to : Doç.Dr Sema UĞURALP
• Department of Pediatric Surgery, Turgut Ozal Medical Center, Inonu University, Faculty of Medicine, 44069 Malatya, Turkey. Phone :[phone] Fax : [phone]
• E-mail : [e-mail]