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Melatoninin Superoksit Yakalama Kapasitesinin In Vitro incelenmesi

Year 2000, Volume: 7 Issue: 3, - , 01.06.2000

Abstract

Aim: In vitro assay of superoxide scavenging capacity of melatonin. Materials and methods: Scavenging capacity of melatonin for superoxide radicals produced by xanthine-xanthine oxidase system was Investigated by using Fridovich I. method. Results and discussion: Melatonin exhibited superoxide scavenging activity ¡n a dose-dependent manner up to 45 pg/mL and activity was calculated to be 0.046 ±0.009 SOD equivalent units / pg of melatonin (n=9). A concentration of approximately 18 pg / mL melatonin served as one unit of superoxide dismutase enzyme. Key words: Melatonin, superoxide scavenging activity, oxidative stress, antioxidant.

AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN

Year 2000, Volume: 7 Issue: 3, - , 01.06.2000

Abstract

Amaç: Melatoninln radikal süpürücü kapasitesinin in vitro koşullarda İncelenmesi amaçlandı. Materyal ve metot: Ksantin-ksantin oksidaz sisteminde oluşturulan superoksit radikallerinin melatonin tarafından süpürüldüğü sitokrom c kullanılarak Fridovich I. yöntemi He araştırıldı. Bulgular ve sonuç: Çalışma bulgularımız melatoninln in vitro koşullarda da superoksit radikallerine karşı anlamlı ölçüde temizleyici etkiyi gösterdiği yönündedir. Anahtar kelimeler:Melatonln,superoksit,süpürücü aktivlte, oksldatifstres,antloksidan

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Details

Primary Language Turkish
Journal Section Articles
Authors

Kadir Batçıoglu This is me

A. Alev Karagözler This is me

İ. Çetin Öztürk This is me

Aysun Bay This is me

M. Engin Gözükara This is me

Publication Date June 1, 2000
Published in Issue Year 2000 Volume: 7 Issue: 3

Cite

APA Batçıoglu, K., Karagözler, A. A., Öztürk, İ. Ç., Bay, A., et al. (2000). AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN. Journal of Turgut Ozal Medical Center, 7(3).
AMA Batçıoglu K, Karagözler AA, Öztürk İÇ, Bay A, Gözükara ME. AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN. J Turgut Ozal Med Cent. June 2000;7(3).
Chicago Batçıoglu, Kadir, A. Alev Karagözler, İ. Çetin Öztürk, Aysun Bay, and M. Engin Gözükara. “AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN”. Journal of Turgut Ozal Medical Center 7, no. 3 (June 2000).
EndNote Batçıoglu K, Karagözler AA, Öztürk İÇ, Bay A, Gözükara ME (June 1, 2000) AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN. Journal of Turgut Ozal Medical Center 7 3
IEEE K. Batçıoglu, A. A. Karagözler, İ. Ç. Öztürk, A. Bay, and M. E. Gözükara, “AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN”, J Turgut Ozal Med Cent, vol. 7, no. 3, 2000.
ISNAD Batçıoglu, Kadir et al. “AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN”. Journal of Turgut Ozal Medical Center 7/3 (June 2000).
JAMA Batçıoglu K, Karagözler AA, Öztürk İÇ, Bay A, Gözükara ME. AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN. J Turgut Ozal Med Cent. 2000;7.
MLA Batçıoglu, Kadir et al. “AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN”. Journal of Turgut Ozal Medical Center, vol. 7, no. 3, 2000.
Vancouver Batçıoglu K, Karagözler AA, Öztürk İÇ, Bay A, Gözükara ME. AN ASSAY FOR THE IN VITRO DEMONSTRATION OF SUPEROXIDE SCAVENGING CAPACITY OF MELATONIN. J Turgut Ozal Med Cent. 2000;7(3).