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Helical Tomotherapy with Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports

Year 2015, Volume: 22 Issue: 2, 103 - 105, 09.12.2015

Abstract

Abstract

Inoperable malignant tumours of the skull base have poor prognosis. The aim of treatment is commonly to provide a better quality of life with the local control of the disease. This paper presents the case of 2 patients with skull base tumours who were admitted to our clinic and treated with intensity modulated radiotherapy with tomotherapy. In both cases, subjective side effects and complaints decreased through the application of an average dose of 54Gy. Our article concludes with an evaluation of the effectiveness of helical tomotherapy with references to the lietrature.

Key Words: Radiotherapy; skull base tumours; tomotherapy

References

  • Schuller DE, Hart MC, Goodman JH: The surgery of benign and malign neoplasms adjacent to or involving the skullbase. Am J Otolaryngol 1989;10:305-13.
  • Yorulmaz İ, Küçük B, Özgürsoy OB. Malign Kafa Tabanı Tümörlerinin Tedavisinde Prognoz Ve Yaşam Kalitesi. KBB-Forum 2002;1(2).
  • Ivan ME, J Han S, Aghi MK. Tumors of the anterior skull base. Expert Rev Neurother 2014;4:425-38.
  • Hug EB1, Slater JD. Proton radiation therapy for chordomas and chondrosarcomas of the skull base.. Neurosurg Clin N Am 2000;4:627-38.
  • Jambhekar NA, Rekhi B, Thorat K, Dikshit R, Agrawal M, Puri A. Revisiting chordoma with brachyury, a "new age" marker: analysis of a validation study on 51 cases. Arch Pathol Lab Med 2010;8:1181-7.
  • Chen AM, Cheng S, Farwell DG, Luu Q, Donald PJ, Boggan J et al. Utility of daily image guidance with intensity-modulated radiotherapy for tumors of the base of skull. Head Neck 2012;6:763-70.
  • Combs SE, Adeberg S, Dittmar JO, Welzel T, Rieken S, Habermehl D, Huber PE, Debus J. Skull base meningiomas: Long-term results and patient self-reported outcome in 507 patients treated with fractionated stereotactic radiotherapy (FSRT) or intensity modulated radiotherapy (IMRT). Radiother Oncol 2013;2:186-91.
  • Ernst-Stecken A, Lambrecht U, Ganslandt O, Mueller R, Fahlbusch R, Sauer R, et al. Radiosurgery of small skull-base lesions. No advantage for intensitymodulated stereotactic radiosurgery versus conformal arc technique. Strahlenther Onkol 2005;181:336–44.

Journal Of Turgut Ozal Medical Center

Year 2015, Volume: 22 Issue: 2, 103 - 105, 09.12.2015

Abstract

Kafa tabanı tümörlerinde cerrahi uygulanmazsa prognoz kötüdür ve tedavi çoğunlukla primer hastalığı kontrol altına alıp hasta için tatminkar yaşam kalitesi sağlamayı amaçlar. Kliniğimize başvuran 2 kafa tabanı tümörüne helikal tomoterapi ile uygulanan yoğunluk ayarlı radyoterapi sonuçları tartışılmıştır. Her iki hastamızda da subjektif yakınmalarda azalma görülmüştür. Hastalarımıza ortalama 54 Gy radyoterapi uygulanmıştır Bu makalede kafa tabanı tümörü nedeniyle cerrahi rezeksiyon uygulanamayan 2 hastada helikal tomoterapinin etkinliği tartışılmaya çalışılmıştır

References

  • Schuller DE, Hart MC, Goodman JH: The surgery of benign and malign neoplasms adjacent to or involving the skullbase. Am J Otolaryngol 1989;10:305-13.
  • Yorulmaz İ, Küçük B, Özgürsoy OB. Malign Kafa Tabanı Tümörlerinin Tedavisinde Prognoz Ve Yaşam Kalitesi. KBB-Forum 2002;1(2).
  • Ivan ME, J Han S, Aghi MK. Tumors of the anterior skull base. Expert Rev Neurother 2014;4:425-38.
  • Hug EB1, Slater JD. Proton radiation therapy for chordomas and chondrosarcomas of the skull base.. Neurosurg Clin N Am 2000;4:627-38.
  • Jambhekar NA, Rekhi B, Thorat K, Dikshit R, Agrawal M, Puri A. Revisiting chordoma with brachyury, a "new age" marker: analysis of a validation study on 51 cases. Arch Pathol Lab Med 2010;8:1181-7.
  • Chen AM, Cheng S, Farwell DG, Luu Q, Donald PJ, Boggan J et al. Utility of daily image guidance with intensity-modulated radiotherapy for tumors of the base of skull. Head Neck 2012;6:763-70.
  • Combs SE, Adeberg S, Dittmar JO, Welzel T, Rieken S, Habermehl D, Huber PE, Debus J. Skull base meningiomas: Long-term results and patient self-reported outcome in 507 patients treated with fractionated stereotactic radiotherapy (FSRT) or intensity modulated radiotherapy (IMRT). Radiother Oncol 2013;2:186-91.
  • Ernst-Stecken A, Lambrecht U, Ganslandt O, Mueller R, Fahlbusch R, Sauer R, et al. Radiosurgery of small skull-base lesions. No advantage for intensitymodulated stereotactic radiosurgery versus conformal arc technique. Strahlenther Onkol 2005;181:336–44.
There are 8 citations in total.

Details

Primary Language ingilizce
Journal Section Articles
Authors

Kemal Ekici This is me

Öztun Temelli This is me

Cemal Ekici This is me

Akif Durak This is me

Publication Date December 9, 2015
Published in Issue Year 2015 Volume: 22 Issue: 2

Cite

APA Ekici, K., Temelli, Ö., Ekici, C., Durak, A. (2015). Helical Tomotherapy with Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports. Journal of Turgut Ozal Medical Center, 22(2), 103-105.
AMA Ekici K, Temelli Ö, Ekici C, Durak A. Helical Tomotherapy with Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports. J Turgut Ozal Med Cent. December 2015;22(2):103-105.
Chicago Ekici, Kemal, Öztun Temelli, Cemal Ekici, and Akif Durak. “Helical Tomotherapy With Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports”. Journal of Turgut Ozal Medical Center 22, no. 2 (December 2015): 103-5.
EndNote Ekici K, Temelli Ö, Ekici C, Durak A (December 1, 2015) Helical Tomotherapy with Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports. Journal of Turgut Ozal Medical Center 22 2 103–105.
IEEE K. Ekici, Ö. Temelli, C. Ekici, and A. Durak, “Helical Tomotherapy with Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports”, J Turgut Ozal Med Cent, vol. 22, no. 2, pp. 103–105, 2015.
ISNAD Ekici, Kemal et al. “Helical Tomotherapy With Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports”. Journal of Turgut Ozal Medical Center 22/2 (December 2015), 103-105.
JAMA Ekici K, Temelli Ö, Ekici C, Durak A. Helical Tomotherapy with Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports. J Turgut Ozal Med Cent. 2015;22:103–105.
MLA Ekici, Kemal et al. “Helical Tomotherapy With Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports”. Journal of Turgut Ozal Medical Center, vol. 22, no. 2, 2015, pp. 103-5.
Vancouver Ekici K, Temelli Ö, Ekici C, Durak A. Helical Tomotherapy with Intensity Modulated and Image Guided Radiotherapy in Skull Base Tumors: Two Case Reports. J Turgut Ozal Med Cent. 2015;22(2):103-5.