Abstract
Febrile seizure is the most common, age-dependant, benign, and fever-related convulsion of childhood. Its pathogenesis is still not clear. Fever causing febrile seizures is usually associated with viral infections, mostly upper respiratory tract infections, otitis media, tonsillitis, or urinary tract infections. The incidence of febrile convulsions during gastroenteritis is lower and gastroenteritis is thought to exert a protective feature in febril seizures. Although the most common pathogen in gastroeneritis is the rotavirus, adenovirus and small round viruses are also frequently reported. We aim to review the pathogenesis of febrile seizures and discuss vaccination in selected groups with known pathogens while discussing a patient with febrile seizures during adenovirus gastroenteritis.
Key Words: Adenovirus Gastroenteritis; Febrile Seizure; Pathogenesis.
Keywords
References
- Millichap JG, Millichap JJ. Role of viral infections in the etiology of febril seizures. Ped Neuro 2006;35:165-72.
- Shinnar S, Glauser TA. Febril Seizures. J Child Neurol 2002;17:44-52.
- Caul EO. Viral gatroenteritis: small round structured viruses, caliciviruses and astroviruses. Part 2. The epidemiological perspective. J Clin Pathol 1996;49:959-64.
- Commission on Epidemiology and Prognosis. International League Against Epilepsy Guidelines for epidemiologic studies on epilepsy. Epilepsia 1993;34:592-6.
- Shinnar S. Febril Seizures. In: Harvey S. Singer, Erich H Kossoff, Adam L Hartman, Thomas O Crawford. Treatment of Pediatric Neurologic Dsisorders. Taylor-Francis Group, Boca Raton 2005;73-8.
- Nakayama J. Progress in serching for the febrile seizure susceptibility genes. Brain Dev 2009;31:359-65.
- Shinnar S. Febril Seizures. In: Kenneth Swaiman, Stephen Ashwal, Dona M. Ferreiro. Pediatric Neurology Principles and Practice. Fourth ed. Mosby Comp. Philadelphia 2006;1079-89.
- Baulac S, Gourfinkel-An I, Nabbout R, Huberfeld G, Serratosa J, Leguem E, et al. Fever, genes and epilepsy. Lancet Neurol 2004;3:421-30.
- Lee WL, Ong HT. A febrile seizures associated with minor infections: comparison with febrile seizures and unprovoked seizures. Ped Neurol 2004;31:157-64.
- Huang YC, Huang SL, Chen SP, Huang YL, Huang CG, Tsao KC, et al. Adenovirus infection associated with central nervous system dysfunction in children. J of Clin Virol 2013;57:300-4.
- Andrew RD. Seizure and acute osmotic change: clinical and neurophysiological aspect. J Neurol Sci 1991;101:7-18.
Abstract
Febril konvülziyon, çocukluk çağının en sık görülen, yaşa bağımlı, benign ve ateşle ortaya çıkan konvülziyonudur. Patogenezi halen çok iyi aydınlatılamamıştır. Febril konvülziyonda ateş genellikle viral enfeksiyonlarla ilişkilidir ve sıklıkla üst solunum yolu enfeksiyonları, otitis media, tonsillit, idrar yolu enfeksiyonlarından kaynaklanır.Gastroenterit sırasında febril konvülziyon insidansı düşük bulunmuştur ve gastroenteritin febril konvülziyondan koruyucu özellik gösterdiği düşünülmektedir. Gastroeneritlerde en sık görülen etken rotavirüs olsa da adenovirüs ve küçük yuvarlak yapılı virüsler de sık bildirilen patojenlerdir. Adenovirüs gastroenteriti sırasında nöbet geçiren bir hastayı tartışırken, febril konvülziyon patogenezini gözden geçirmek, ateşli nöbete sebep olan patojenleri saptayarak seçilmiş gruplara aşı uygulamasını tartışmak istedik
References
- Millichap JG, Millichap JJ. Role of viral infections in the etiology of febril seizures. Ped Neuro 2006;35:165-72.
- Shinnar S, Glauser TA. Febril Seizures. J Child Neurol 2002;17:44-52.
- Caul EO. Viral gatroenteritis: small round structured viruses, caliciviruses and astroviruses. Part 2. The epidemiological perspective. J Clin Pathol 1996;49:959-64.
- Commission on Epidemiology and Prognosis. International League Against Epilepsy Guidelines for epidemiologic studies on epilepsy. Epilepsia 1993;34:592-6.
- Shinnar S. Febril Seizures. In: Harvey S. Singer, Erich H Kossoff, Adam L Hartman, Thomas O Crawford. Treatment of Pediatric Neurologic Dsisorders. Taylor-Francis Group, Boca Raton 2005;73-8.
- Nakayama J. Progress in serching for the febrile seizure susceptibility genes. Brain Dev 2009;31:359-65.
- Shinnar S. Febril Seizures. In: Kenneth Swaiman, Stephen Ashwal, Dona M. Ferreiro. Pediatric Neurology Principles and Practice. Fourth ed. Mosby Comp. Philadelphia 2006;1079-89.
- Baulac S, Gourfinkel-An I, Nabbout R, Huberfeld G, Serratosa J, Leguem E, et al. Fever, genes and epilepsy. Lancet Neurol 2004;3:421-30.
- Lee WL, Ong HT. A febrile seizures associated with minor infections: comparison with febrile seizures and unprovoked seizures. Ped Neurol 2004;31:157-64.
- Huang YC, Huang SL, Chen SP, Huang YL, Huang CG, Tsao KC, et al. Adenovirus infection associated with central nervous system dysfunction in children. J of Clin Virol 2013;57:300-4.
- Andrew RD. Seizure and acute osmotic change: clinical and neurophysiological aspect. J Neurol Sci 1991;101:7-18.
Details
| Primary Language | Tr |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | December 11, 2015 |
| Published in Issue | Year 2015 Volume: 22 Issue: 2 |
