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Our Experience with Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients

Year 2015, Volume: 22 Issue: 3, 176 - 179, 14.12.2015

Abstract

Aim: Widely used in many indications in dermatology practice, narrow-band ultraviolet B is a kind of ultraviolet with a wavelength usually condensing at 312nm. Our aim in this study is to introduce our 15-year experience with narrow-band UVB on 205 patients.

Materials and Methods: Gender, diagnosis, distribution of lesions, beginning dose, maximum dose, number of sessions, and cumulative dose of patients treated with narrow band UVB were retrospectively studied.

Results: The mean age of patients was 37,2 years. 44,4% of the patients was males, 55,6% was females. 34,1% of the patients were diagnosed with psoriasis and 14,6% of the patients with mycosis fungoides. 73,7% of distribution of lesions was diffused, 28% was central, and 26% was peripheral. The mean number of sessions was 27,1 and the mean cumulative dose was 21070 mJ/cm2 in the first treatment. The mean starting dose was 125,4 mJ/cm2 and the mean maximum dose was 21070 mJ/cm2.

Conclusion: Differences between the means of the number of sessions, maximum doses, cumulative doses, and diseases were statistically significant.

Key Words: Mycosis Fungoides; Narrow Band UVB; Phototherapy; Psoriasis.

References

  • Dogra S, Kanwar AJ. Narrow band UVB phototherapy in dermatology. Indian J Dermatol Venereol Leprol 2004;70(4):205-9.
  • Roelandts R. The history of phototherapy: Something new under the sun? J Am Acad Dermatol 2002;46:926-30.
  • Hönigsmann H. Phototherapy for psoriasis. Clin Exp Dermatol 2001;26:343-50.
  • Ibbotson SH, Bilsland D, Cox NH, Dawe RS, Diffey B, Edwards C, et al. British association of dermatologists. An update and guidance on narrowband ultraviolet B phototherapy: a British photodermatology group workshop report. Br J Dermatol 2004;151(2):283-97.
  • El-Ghorr AA, Norval M. Biological effects of narrow-band (311nm TL01) UVB irradiation: a review. J Photochem Photobiol 1997;38:99-106.
  • Hjerppe M, Hasan T, Saksala I, Reunala T. Narrow-band UVB treatment in atopic dermatitis. Acta Derm Venereol 2001;8:439-40.
  • Dawe RS. A quantitative review of studies comparing the efficacy of narrow-band and broad-band ultraviolet B for psoriasis. Br J Dermatol 2003;149:669–72.
  • Molin L. Topical calcipotriol combined with phototherapy for psoriasis: the results of two randomized trials and a review of literatüre. Calcipotriol-UVB study group. Dermatology 1999;198:375-81.
  • George SA, Bilsland DJ, Johnson BE, Ferguson J. Narrow-band (TL-01) UVB air-conditioned phototherapy for chronic severe adult atopic dermatitis. Br J Dermatol 1993;128:49-56.
  • Pacifico A, Leone G. Photo(chemo)therapy for vitiligo. Photodermatol Photoimmunol Photomed 2011;27(5):261-77.
  • Lee E, Koo J, Berger T. UVB phototherapy and skin cancer risk: a review of the literature. Int J Dermatol 2005;44:355-60.
  • Friedland R, David M, Feinmesser M, Barzilai A, Hodak E. NB-UVB (311-312 nm)-induced lentigines in patients with mycosis fungoides: a new adverse effect of phototherapy. J Eur Acad Dermatol Venereol 2012;26(9):1158-62.

Journal of Turgut Ozal Medical Center

Year 2015, Volume: 22 Issue: 3, 176 - 179, 14.12.2015

Abstract

Amaç: Dermatoloji pratiğinde birçok endikasyonda kullanım alanı bulan dar bant ultraviyole B, dalga boyu genellikle 312nm’de yoğunlaşmış bir ultraviyole B türüdür. Bu çalışmadaki amacımız, 205 hastamızı içeren 15 yıllık dar bant UVB deneyimimizi ortaya koymaktır. Gereç ve Yöntem: Dar bant UVB tedavisi alan hastaların yaşı, cinsiyeti, tanısı, lezyonlarının yerleşim yeri, başlangıç dozu, maksimum dozu, seans sayısı ve toplamda aldığı doz retrospektif olarak değerlendirildi. Bulgular: Hastaların yaş ortalaması 37,2 yıldı. Hastaların %44,4’ü erkek, %55,6’sı kadındı. Hastaların %34,1’i psoriazis ve %14,6’sı mikozis fungoides tanısı almıştı. Lezyonların %73,7’si diffüz, %28’i santral, %26’sı ise periferik yerleşim gösteriyordu. İlk tedavi periyodundaki ortalama seans sayısı 27,1, toplam doz ortalaması ise 21070 mJ/cm2 idi. Başlangıç dozu ortalaması 125,4 mJ/cm2, maksimum doz ortalaması 1463mJ/cm2 olarak saptandı. Sonuç: Hastalıklar ile ortalama seans sayıları, maksimum doz ve toplam doz arasındaki farklar istatiksel olarak anlamlıydı

References

  • Dogra S, Kanwar AJ. Narrow band UVB phototherapy in dermatology. Indian J Dermatol Venereol Leprol 2004;70(4):205-9.
  • Roelandts R. The history of phototherapy: Something new under the sun? J Am Acad Dermatol 2002;46:926-30.
  • Hönigsmann H. Phototherapy for psoriasis. Clin Exp Dermatol 2001;26:343-50.
  • Ibbotson SH, Bilsland D, Cox NH, Dawe RS, Diffey B, Edwards C, et al. British association of dermatologists. An update and guidance on narrowband ultraviolet B phototherapy: a British photodermatology group workshop report. Br J Dermatol 2004;151(2):283-97.
  • El-Ghorr AA, Norval M. Biological effects of narrow-band (311nm TL01) UVB irradiation: a review. J Photochem Photobiol 1997;38:99-106.
  • Hjerppe M, Hasan T, Saksala I, Reunala T. Narrow-band UVB treatment in atopic dermatitis. Acta Derm Venereol 2001;8:439-40.
  • Dawe RS. A quantitative review of studies comparing the efficacy of narrow-band and broad-band ultraviolet B for psoriasis. Br J Dermatol 2003;149:669–72.
  • Molin L. Topical calcipotriol combined with phototherapy for psoriasis: the results of two randomized trials and a review of literatüre. Calcipotriol-UVB study group. Dermatology 1999;198:375-81.
  • George SA, Bilsland DJ, Johnson BE, Ferguson J. Narrow-band (TL-01) UVB air-conditioned phototherapy for chronic severe adult atopic dermatitis. Br J Dermatol 1993;128:49-56.
  • Pacifico A, Leone G. Photo(chemo)therapy for vitiligo. Photodermatol Photoimmunol Photomed 2011;27(5):261-77.
  • Lee E, Koo J, Berger T. UVB phototherapy and skin cancer risk: a review of the literature. Int J Dermatol 2005;44:355-60.
  • Friedland R, David M, Feinmesser M, Barzilai A, Hodak E. NB-UVB (311-312 nm)-induced lentigines in patients with mycosis fungoides: a new adverse effect of phototherapy. J Eur Acad Dermatol Venereol 2012;26(9):1158-62.
There are 12 citations in total.

Details

Primary Language Tr
Journal Section Articles
Authors

Okan Kızılyel This is me

Ömer Faruk Elmas

Mahmut Sami Metin This is me

Akın Aktaş This is me

Publication Date December 14, 2015
Published in Issue Year 2015 Volume: 22 Issue: 3

Cite

APA Kızılyel, O., Elmas, Ö. F., Metin, M. S., Aktaş, A. (2015). Our Experience with Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients. Journal of Turgut Ozal Medical Center, 22(3), 176-179.
AMA Kızılyel O, Elmas ÖF, Metin MS, Aktaş A. Our Experience with Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients. J Turgut Ozal Med Cent. December 2015;22(3):176-179.
Chicago Kızılyel, Okan, Ömer Faruk Elmas, Mahmut Sami Metin, and Akın Aktaş. “Our Experience With Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients”. Journal of Turgut Ozal Medical Center 22, no. 3 (December 2015): 176-79.
EndNote Kızılyel O, Elmas ÖF, Metin MS, Aktaş A (December 1, 2015) Our Experience with Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients. Journal of Turgut Ozal Medical Center 22 3 176–179.
IEEE O. Kızılyel, Ö. F. Elmas, M. S. Metin, and A. Aktaş, “Our Experience with Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients”, J Turgut Ozal Med Cent, vol. 22, no. 3, pp. 176–179, 2015.
ISNAD Kızılyel, Okan et al. “Our Experience With Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients”. Journal of Turgut Ozal Medical Center 22/3 (December 2015), 176-179.
JAMA Kızılyel O, Elmas ÖF, Metin MS, Aktaş A. Our Experience with Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients. J Turgut Ozal Med Cent. 2015;22:176–179.
MLA Kızılyel, Okan et al. “Our Experience With Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients”. Journal of Turgut Ozal Medical Center, vol. 22, no. 3, 2015, pp. 176-9.
Vancouver Kızılyel O, Elmas ÖF, Metin MS, Aktaş A. Our Experience with Narrow-Band UVB for 15 Years: A Retrospective Study of 205 Patients. J Turgut Ozal Med Cent. 2015;22(3):176-9.