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Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy

Year 2019, Volume: 29 Issue: 2, 61 - 66, 03.06.2019

Abstract

Objectives: This study aims to evaluate volumetric and morphological changes following CyberKnife radiotherapy of vestibular schwannomas. Patients and Methods: Between March 2011 and December 2013, a total of 39 patients 15 males, 24 females; mean age 52 years; range, 19 to 86 years who underwent CyberKnife hypofractionated radiotherapy were retrospectively analyzed. Tumor volume calculations were done by manual segmentation. Tumor morphology was classified by arbitrary cystic scaling. Local tumor control, tumor progression, transient swelling rates, and changes in tumor morphology were evaluated. Results: Local tumor control and transient swelling rates were 87% and 46%, respectively. Cystic tumors responded better than solid tumors to treatment as evidenced by volume reduction rates 87% vs. 58% , although local control rates were not significantly different 93% vs. 83% . Transient swelling rates were significantly higher in cystic tumors than in solid tumors 67% vs. 29% . Post-treatment volume changes were not correlated with gender, age group, or pre-procedural tumor volume. Conclusion: CyberKnife radiotherapy is an effective way of achieving local tumor control in patients with vestibular schwannomas. Although higher rates of volumetric regression would be expected in more cystic tumors than more solid tumors, local control rates are similar.

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There are 19 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Engin Uğur Yardımcı This is me

Melda Apaydın This is me

Fazıl Gelal This is me

Fatih Dağ This is me

Ali Özmezoğlu This is me

Ali Fırat Sarp This is me

Publication Date June 3, 2019
Published in Issue Year 2019 Volume: 29 Issue: 2

Cite

APA Yardımcı, E. U., Apaydın, M., Gelal, F., Dağ, F., et al. (2019). Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. The Turkish Journal of Ear Nose and Throat, 29(2), 61-66.
AMA Yardımcı EU, Apaydın M, Gelal F, Dağ F, Özmezoğlu A, Sarp AF. Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. Tr-ENT. June 2019;29(2):61-66.
Chicago Yardımcı, Engin Uğur, Melda Apaydın, Fazıl Gelal, Fatih Dağ, Ali Özmezoğlu, and Ali Fırat Sarp. “Evaluation of Volumetric and Morphological Changes of Vestibular Schwannomas Following CyberKnife Therapy”. The Turkish Journal of Ear Nose and Throat 29, no. 2 (June 2019): 61-66.
EndNote Yardımcı EU, Apaydın M, Gelal F, Dağ F, Özmezoğlu A, Sarp AF (June 1, 2019) Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. The Turkish Journal of Ear Nose and Throat 29 2 61–66.
IEEE E. U. Yardımcı, M. Apaydın, F. Gelal, F. Dağ, A. Özmezoğlu, and A. F. Sarp, “Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy”, Tr-ENT, vol. 29, no. 2, pp. 61–66, 2019.
ISNAD Yardımcı, Engin Uğur et al. “Evaluation of Volumetric and Morphological Changes of Vestibular Schwannomas Following CyberKnife Therapy”. The Turkish Journal of Ear Nose and Throat 29/2 (June 2019), 61-66.
JAMA Yardımcı EU, Apaydın M, Gelal F, Dağ F, Özmezoğlu A, Sarp AF. Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. Tr-ENT. 2019;29:61–66.
MLA Yardımcı, Engin Uğur et al. “Evaluation of Volumetric and Morphological Changes of Vestibular Schwannomas Following CyberKnife Therapy”. The Turkish Journal of Ear Nose and Throat, vol. 29, no. 2, 2019, pp. 61-66.
Vancouver Yardımcı EU, Apaydın M, Gelal F, Dağ F, Özmezoğlu A, Sarp AF. Evaluation of volumetric and morphological changes of vestibular schwannomas following CyberKnife therapy. Tr-ENT. 2019;29(2):61-6.