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Year 2014, Volume: 16 Issue: 1, 25 - 31, 04.06.2014

Abstract

The Ghrelin is produced primarily by enteroendocrine cells in the gastric mucosa, and increases gastric emptying in normal subjects. The purpose of this study is to determine the differences in the Ghrelin level during different times along the day, and to assess the differences between the athletes and sedentary at the end of Ramadan fasting period of one month. The results indicated that there were no significant difference among the Ghrelin levels of athletes and sedentary during different times through the day (p>0.05). Significant differences were observed between pre- and post-tests mean Ghrelin scores of subjects (p<0.05) without making a separation as an athlete and sedentary. Also, the results indicated no significant difference between repeated Ghrelin measurements of athletes and sedentary (p>0.05). A significant and positive relationship was found in the middle level at the percentages of BMI and body fat of both groups. Moreover, there were significant differences among BMI scores (p<0.01) and body fat % (p<0.05) of the athletes and sedentary. Consequently, fasting during Ramadan did not cause any differentiation on the serum Ghrelin level of athletes and sedentary, but without group differentiation there was significant increase from the initial measurement to the last measurement of the serum Ghrelin level. There was a significant and positive relationship at middle level between BMI and body fat % of both groups of athletes and sedentary. There was a significant relationship, on the other hand, between BMI and repeated Ghrelin measurements of subjects

References

  • Adlouni A, Ghalim N, Benslimane A, Lacerf Jm, Saite R., Fasting During Ramadan Induces a Marked Increase in High- Density Lipoprotein Cholesterol and Decrease In Low-Density Lipoprotein Cholesterol. Ann Nutr Metab, 1997; 41: 242–249.
  • Arvat E, Di Vito L, Broglio F, Papotti M, Muccioli G, Dieguez C, Casanueva Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans. J Endocrinol Invest, 2000; 23: 493–495. E.
  • Nagaya N, Uematsu M, Kojima M, Date Y, Nakazato M, Okumura H, Hosoda H, Shimizu W, Yamagishi M, Oya H, Koh H, Yutani C, Kangawa K. Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: Relationships between ghrelin and anabolic/catabolic factors. Circulation, 2001; 104: 2034–2038.
  • Nakazato M, Murakami N, Date Y, Kojima M, Matsuo H, Kangawa K, Matsukura S. A role for ghrelin in the central regulation of feeding. Nature, 2001; 409: 194–198.
  • Shiiya T, Nakazato M, Mizuta A, Date Y, Mondal MS, Tanaka M, Nozoe SI, Hosada H, Kangawa K, Matsukura S: Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab, 2002; 87: 240-244.
  • Shintani M, Ogawa Y, Ebihara K, Aizawa-Abe M, Miyanaga F, Takaya K, Hayashi M, Kangawa K, Nakao K. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway. Diabetes 2001, 50, 227–232. G, Hosoda K, Kojima
  • Soriano-Guillen L, Barrios V, Campos-Barros A, Argente J. Ghrelin levels in obesity and anorexia nervosa: effect of weight reduction or recuperation. J Pediatr, 2004; 144: 36-42.
  • Souza MJD, Leidy HJ, O’Donnell E, Lasley B, Williams NI. Fasting ghrelin levels in physically active women: relationship with menstrual disturbances and metabolic hormones. The Journal of Clinical Endocrinology & Metabolism, 2004; 89(7): 3536–3542.
  • Tschop M, Smiley DL, Heiman ML: Ghrelin induces adiposity in rodents. Nature, 2000; 407: 908-913.
  • Tschop M, Wawarta R, Riepl RL, Friedrich S, Bidlingmaier M, Landgraf R, Folwaczny C: Post-prandial decrease of circulating human ghrelin levels. J Endocrinol Invest, 2001; 24: RC19- RC21.
  • Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR: Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab, 2001; 86: 5992-5995.
  • Wren AM, Small CJ, Abbott CR, Dhillo WS, Seal LJ, Cohen MA, Batterham RL, Taheri S, Stanley SA, Ghatei MA, Bloom SR: Ghrelin causes hyperphagia and obesity in rats. Diabetes, 2001; 50: 2540-2547.
  • Wren AM, Small CJ, Ward HL, Murphy KG, Dakin CL, Taheri S, Kennedy AR, Roberts GH, Morgan DGA, Ghatei MA, Bloom SR: The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology, 2000; 141: 4325-4328.
  • Zoladz JA, Konturek SJ, Duda K, Majerczak J, Sliwowski Z, Grandys M, Bielanski W. Effect of moderate incremental exercise, performed in fed and fasted state on cardio- respiratory variables and leptin and ghrelin concentrations in young. Healthy Men journal of Physiology and Pharmacology, 2005; 56(1): 63-85.

Studying the serum ghrelin levels of the elite athletes and sedentary controls fasting at the time of Ramadan

Year 2014, Volume: 16 Issue: 1, 25 - 31, 04.06.2014

Abstract

The Ghrelin is produced primarily by enteroendocrine cellsin the gastric mucosa, and increases gastric emptying in normal subjects.The purpose of this study is to determine the differences in the Ghrelin level during different times along the day, and to assess the differences between the athletes and sedentary at the end of Ramadan fasting period of one month. The results indicated that there were no significant difference among the Ghrelin levels of athletes and sedentary during different times through the day (p>0.05). Significant differences were observed between pre- and post-tests mean Ghrelin scores of subjects (p<0.05) without making a separation as an athlete and sedentary. Also, the results indicated no significant difference between repeated Ghrelin measurements of athletes and sedentary (p>0.05). A significant and positive relationship was found in the middle level at the percentages of BMI and body fat of both groups. Moreover, there were significant differences among BMI scores (p<0.01) and body fat % (p<0.05) of the athletes and sedentary. Consequently, fasting during Ramadan did not cause any differentiation on the serum Ghrelin level of athletes and sedentary, but without group differentiation there was significant increase from the initial measurement to the last measurement of the serum Ghrelin level. There was a significant and positive relationship at middle level between BMI and body fat % of both groups of athletes and sedentary. There was a significant relationship, on the other hand, between BMI and repeated Ghrelin measurements of subjects.

References

  • Adlouni A, Ghalim N, Benslimane A, Lacerf Jm, Saite R., Fasting During Ramadan Induces a Marked Increase in High- Density Lipoprotein Cholesterol and Decrease In Low-Density Lipoprotein Cholesterol. Ann Nutr Metab, 1997; 41: 242–249.
  • Arvat E, Di Vito L, Broglio F, Papotti M, Muccioli G, Dieguez C, Casanueva Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans. J Endocrinol Invest, 2000; 23: 493–495. E.
  • Nagaya N, Uematsu M, Kojima M, Date Y, Nakazato M, Okumura H, Hosoda H, Shimizu W, Yamagishi M, Oya H, Koh H, Yutani C, Kangawa K. Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: Relationships between ghrelin and anabolic/catabolic factors. Circulation, 2001; 104: 2034–2038.
  • Nakazato M, Murakami N, Date Y, Kojima M, Matsuo H, Kangawa K, Matsukura S. A role for ghrelin in the central regulation of feeding. Nature, 2001; 409: 194–198.
  • Shiiya T, Nakazato M, Mizuta A, Date Y, Mondal MS, Tanaka M, Nozoe SI, Hosada H, Kangawa K, Matsukura S: Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab, 2002; 87: 240-244.
  • Shintani M, Ogawa Y, Ebihara K, Aizawa-Abe M, Miyanaga F, Takaya K, Hayashi M, Kangawa K, Nakao K. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway. Diabetes 2001, 50, 227–232. G, Hosoda K, Kojima
  • Soriano-Guillen L, Barrios V, Campos-Barros A, Argente J. Ghrelin levels in obesity and anorexia nervosa: effect of weight reduction or recuperation. J Pediatr, 2004; 144: 36-42.
  • Souza MJD, Leidy HJ, O’Donnell E, Lasley B, Williams NI. Fasting ghrelin levels in physically active women: relationship with menstrual disturbances and metabolic hormones. The Journal of Clinical Endocrinology & Metabolism, 2004; 89(7): 3536–3542.
  • Tschop M, Smiley DL, Heiman ML: Ghrelin induces adiposity in rodents. Nature, 2000; 407: 908-913.
  • Tschop M, Wawarta R, Riepl RL, Friedrich S, Bidlingmaier M, Landgraf R, Folwaczny C: Post-prandial decrease of circulating human ghrelin levels. J Endocrinol Invest, 2001; 24: RC19- RC21.
  • Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR: Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab, 2001; 86: 5992-5995.
  • Wren AM, Small CJ, Abbott CR, Dhillo WS, Seal LJ, Cohen MA, Batterham RL, Taheri S, Stanley SA, Ghatei MA, Bloom SR: Ghrelin causes hyperphagia and obesity in rats. Diabetes, 2001; 50: 2540-2547.
  • Wren AM, Small CJ, Ward HL, Murphy KG, Dakin CL, Taheri S, Kennedy AR, Roberts GH, Morgan DGA, Ghatei MA, Bloom SR: The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology, 2000; 141: 4325-4328.
  • Zoladz JA, Konturek SJ, Duda K, Majerczak J, Sliwowski Z, Grandys M, Bielanski W. Effect of moderate incremental exercise, performed in fed and fasted state on cardio- respiratory variables and leptin and ghrelin concentrations in young. Healthy Men journal of Physiology and Pharmacology, 2005; 56(1): 63-85.
There are 14 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Hasan Eker

İbrahim Cıcıoglu This is me

İlhan Yetkın This is me

Ozlem Gulbahar This is me

C. Berkan Alpay This is me

Publication Date June 4, 2014
Published in Issue Year 2014 Volume: 16 Issue: 1

Cite

APA Eker, H., Cıcıoglu, İ., Yetkın, İ., Gulbahar, O., et al. (2014). Studying the serum ghrelin levels of the elite athletes and sedentary controls fasting at the time of Ramadan. Turkish Journal of Sport and Exercise, 16(1), 25-31. https://doi.org/10.15314/tjse.19612
AMA Eker H, Cıcıoglu İ, Yetkın İ, Gulbahar O, Alpay CB. Studying the serum ghrelin levels of the elite athletes and sedentary controls fasting at the time of Ramadan. Turk J Sport Exe. June 2014;16(1):25-31. doi:10.15314/tjse.19612
Chicago Eker, Hasan, İbrahim Cıcıoglu, İlhan Yetkın, Ozlem Gulbahar, and C. Berkan Alpay. “Studying the Serum Ghrelin Levels of the Elite Athletes and Sedentary Controls Fasting at the Time of Ramadan”. Turkish Journal of Sport and Exercise 16, no. 1 (June 2014): 25-31. https://doi.org/10.15314/tjse.19612.
EndNote Eker H, Cıcıoglu İ, Yetkın İ, Gulbahar O, Alpay CB (June 1, 2014) Studying the serum ghrelin levels of the elite athletes and sedentary controls fasting at the time of Ramadan. Turkish Journal of Sport and Exercise 16 1 25–31.
IEEE H. Eker, İ. Cıcıoglu, İ. Yetkın, O. Gulbahar, and C. B. Alpay, “Studying the serum ghrelin levels of the elite athletes and sedentary controls fasting at the time of Ramadan”, Turk J Sport Exe, vol. 16, no. 1, pp. 25–31, 2014, doi: 10.15314/tjse.19612.
ISNAD Eker, Hasan et al. “Studying the Serum Ghrelin Levels of the Elite Athletes and Sedentary Controls Fasting at the Time of Ramadan”. Turkish Journal of Sport and Exercise 16/1 (June 2014), 25-31. https://doi.org/10.15314/tjse.19612.
JAMA Eker H, Cıcıoglu İ, Yetkın İ, Gulbahar O, Alpay CB. Studying the serum ghrelin levels of the elite athletes and sedentary controls fasting at the time of Ramadan. Turk J Sport Exe. 2014;16:25–31.
MLA Eker, Hasan et al. “Studying the Serum Ghrelin Levels of the Elite Athletes and Sedentary Controls Fasting at the Time of Ramadan”. Turkish Journal of Sport and Exercise, vol. 16, no. 1, 2014, pp. 25-31, doi:10.15314/tjse.19612.
Vancouver Eker H, Cıcıoglu İ, Yetkın İ, Gulbahar O, Alpay CB. Studying the serum ghrelin levels of the elite athletes and sedentary controls fasting at the time of Ramadan. Turk J Sport Exe. 2014;16(1):25-31.

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