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Year 2019, Volume: 21 Issue: 1, 96 - 109, 30.04.2019
https://doi.org/10.15314/tsed.542914

Abstract

References

  • REFERENCES
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Bipolar disorder and leisure-time physical activity: results from a national survey of Canadians. Ment. Health Phys. Act. 2, 65–70. Doi:10.1016/j.mhpa.2009.09.003Carek, P. J., Laibstain, S. E., Carek S. M. (2011). Exercise for the treatment of depression and anxiety. Int. J. Psychiatry Med. 41, 15–28. Doi:10.2190/PM.41.1.c Cooper, S.J., Reynolds, G.P., Barnes, T., England, E., Haddad, P.M., Heald, A., Holt, R., Lingford-Hughes, A., Osborn, D., McGowan, O., Patel, M..X., Paton, C., Reid, P., Shiers, D., Smith, J. (2016). BAP guidelines on the management of weight gain, metabolic disturbances and cardiovascular risk associated with psychosis and antipsychotic drug treatment. J Psychopharmacol. 30(8):717–748. Doi: 10.1177/ 0269881116645254. Creta, E., Fabbri, C., Serretti, A. (2015). Genetics of second-generation antipsychotic and mood stabilizer-induced weight gain in bipolar disorder: common and specific effects of key regulators of fat-mass homoeostasis genes. Pharmacogenet Genomics. 2015 Jul;25(7): 354-62. Doi: 10.1097/FPC.0000000000000144.Crump, C., Sundquist, K., Winkleby, M.A., Sundquist, J. (2013). Comorbidities and mortality in bipolar disorder: a Swedish national cohort study. JAMA Psychiatry 70, 931–939. Doi:10.1001/jamapsychiatry.2013.1394 Daumit, G. L., Dickerson, F. B., Wang, N. Y., Dalcin, A., Jerome, G. J., Anderson, C. A. M, Young, D. R., Frick, K. D., Yu, A., Gennusa, J. V., Oefinger, M., Crum, R. M., Charleston, J., Casagrande, S. S., Eliseo Guallar, E., Goldberg, R. W., Campbell, L. M., Lawrence J. Appel, L. J. (2013). A behavioral weight-loss intervention in persons with serious mental illness. N. Engl. J. Med. 368, 1594–1602. Doi:10.1056/NEJMoa1214530De Hert, M., Detraux, J., Van Winkel, R., Yu, W., Correll, C.U. (2011). Metabolic and cardiovascular adverse effects associated with antipsychotic drugs. Nat Rev Endocrinol. 8(2):114–126. Doi: 10.1038/nrendo.2011.156.De Hert, M., Yu, W., Detraux, J., Sweers, K., Van Winkel, R., Correll, C.U. (2012). Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis. CNS Drugs. 26(9):733–759. Doi: 10.2165/11634500-000000000-00000.Detke, H.C., DelBello, M.P., Landry, J., Hoffmann, V.P., Heinloth, A., Dittman, R.W. (2016). A 52-Week Study of Olanzapine with a Randomized Behavioral Weight Counseling Intervention in Adolescents with Schizophrenia or Bipolar I Disorder. J Child Adolesc Psychopharmacol. 2016 Dec;26(10):922-934. Epub 2016 Sep 27. Doi:10.1089 /cap. 2016.0010Dodd, S., Brnabic, A. J., Berk, L., Fitzgerald, P. B., De Castella, A. R., Filia, S., Filia, K., Kelin, K., Smith, M., Montgomery, W., Kulkarni, J., Berk, M. (2010). A prospective study of the impact of smoking on outcomes in bipolar and schizoaffective disorder. Compr. Psychiatry 51, 504–509. Doi:10.1016/ j.comppsych. 2009.12.001 Dome, P., Gonda, X., Rihmer, Z. (2012). Effects of smoking on health outcomes in bipolar disorder with a special focus on suicidal behavior. Neuropsychiatry 2, 429–441 Doi: 10.2217/npy.12.51Fang, F., Wang, Z., Wu, R., Calabrese, J.R., Gao, K. (2017). Is there a 'weight neutral' second-generation antipsychotic for bipolar disorder?. Expert Rev Neurother. 2017 Apr; 17(4): 407-418. Doi: 10.1080/14737175.2016.1276284. Fleischhacker, W.W., Heikkinen, M.E., Olie, J. P., Landsberg, W., Dewaele, P., McQuade, R. D., Loze, J. Y., Hennicken, D., Kerselaers, W. (2010). Effects of adjunc-tive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial. Int J Neuro-psychopharmacol. 13(8): 1115–1125. Doi: 10.1017/S1461145710000490.Goldberg, J. (2017). Antipsychotic Medication for Bipolar Disorder; Side Effects of Antipsychotic Drugs. WebMD Medical Reference. https://www.webmd.com/bipolar-disorder/ guide/ antipsychotic-medication#1-2.Gonçalves, P., Araujo, J. R., Martel, F. (2015). Antipsychotics-induced metabolic alterations: focus on adipose tissue and molecular mechanisms. Eur Neuropsychopharmacol. 25(1): 1–16. Doi: 10.1016/j.euroneuro.2014.11.008.Grohol, J. (2018). Atypical Antipsychotics for Bipolar Disorder. Psych Central. https://psychcentral.com/lib/atypical-antipsychotics-for-bipolar-disorder/.Henderson, D. C., Vincenzi, B., Andrea, N. V., Ulloa, M., Copeland, P. M. (2015). Pathophysiological mechanisms of increased cardiometabolic risk in people with schizophrenia and other severe mental illnesses. Lancet Psychiatry. 2(5):452–464. Doi: 10.1016/S2215-0366(15)00115-7.Janney, C. A., Fagiolini, A., Swartz, H. A., Jakicic, J. M., Holleman, R. G., Richardson, C. R. (2014). Are adults with bipolar disorder active? Objectively measured physical activity and sedentary behavior using accelerometry. J. Affect. Disord. 152–154, 498–504. Doi: 10.1016/j.jad.2013.09.009Kilbourne, A. M., Morden, N. E., Austin, K., Ilgen, M., Mccarthy, J. F., Dalack, G., Blow, F. C. (2009). Excess heart-disease-related mortality in a national study of patients with mental disorders: identifying modifiable risk factors. Gen. Hosp. Psychiatry 31, 555–563. Doi:10.1016/j.genhosppsych.2009.07.008 Lasikiewicz, N., Myrissa, K., Hoyland, A., Lawton, C.L. (2014). Psychological benefits of weight loss following behavioural and/or dietary weight loss interventions. A systematic research review. Appetite. 72: 123–137. Doi: 10.1016/j.appet.2013.09.017Leucht, S., Cipriani, A., Spineli, L., Mavridis, D., Orey, D., Richter, F., Samara, M., Barbui, C., Engel, R. R., Geddes, J. R., Kissling, W., Stapf, M. P., Lässig, B., Salanti, G., Davis, J. M. (2013). 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The role of exercıse ın reducıng the sıde effects of antıpsıcotıcs used ın the treatment of bıpolar dısorders

Year 2019, Volume: 21 Issue: 1, 96 - 109, 30.04.2019
https://doi.org/10.15314/tsed.542914

Abstract

ABSTRACT

The study is a systematic evaluation of quantitative studies showing the relationship between drug use and physical activity in investigating the side effects of antipsychotics used in patients who have bipolar disorder.

Bipolar disorder is usually treated with medicine and the side effects of the drugs which are used to increase the body mass index of patients and this causes obesity. This study mainly aims to examine the role of exercise in reducing the side effects of antipsychotics which are used by individuals who have bipolar disorder with using the high-level evidence which was acquired from published systematic reviews and meta-analyzes.

Most antipsychotics cause weight gain; olanzapine and clozapine are seen as the antipsychotics which have highest risk. In the first period after taking antipsychotics, the weight is increasing rapidly, and patients continue to gain weight in the long term. One of the best strategies to prevent this situation is to adapt antipsychotics according to individual needs and to check over weight and other metabolic parameters closely.

The researches which were done and current information in the last 10 years were included in the study. Recent studies have shown that in the patients who have bipolar disorder, physical activity programs can play a significant role in supporting of mental and physical health. We hope that adding exercise to treatment plans for individuals with bipolar disorder may provide side benefits and be guidance for clinical practice, policy and future research.

References

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Pharmacogenet Genomics. 2015 Jul;25(7): 354-62. Doi: 10.1097/FPC.0000000000000144.Crump, C., Sundquist, K., Winkleby, M.A., Sundquist, J. (2013). Comorbidities and mortality in bipolar disorder: a Swedish national cohort study. JAMA Psychiatry 70, 931–939. Doi:10.1001/jamapsychiatry.2013.1394 Daumit, G. L., Dickerson, F. B., Wang, N. Y., Dalcin, A., Jerome, G. J., Anderson, C. A. M, Young, D. R., Frick, K. D., Yu, A., Gennusa, J. V., Oefinger, M., Crum, R. M., Charleston, J., Casagrande, S. S., Eliseo Guallar, E., Goldberg, R. W., Campbell, L. M., Lawrence J. Appel, L. J. (2013). A behavioral weight-loss intervention in persons with serious mental illness. N. Engl. J. Med. 368, 1594–1602. Doi:10.1056/NEJMoa1214530De Hert, M., Detraux, J., Van Winkel, R., Yu, W., Correll, C.U. (2011). Metabolic and cardiovascular adverse effects associated with antipsychotic drugs. Nat Rev Endocrinol. 8(2):114–126. 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Psychiatry 51, 504–509. Doi:10.1016/ j.comppsych. 2009.12.001 Dome, P., Gonda, X., Rihmer, Z. (2012). Effects of smoking on health outcomes in bipolar disorder with a special focus on suicidal behavior. Neuropsychiatry 2, 429–441 Doi: 10.2217/npy.12.51Fang, F., Wang, Z., Wu, R., Calabrese, J.R., Gao, K. (2017). Is there a 'weight neutral' second-generation antipsychotic for bipolar disorder?. Expert Rev Neurother. 2017 Apr; 17(4): 407-418. Doi: 10.1080/14737175.2016.1276284. Fleischhacker, W.W., Heikkinen, M.E., Olie, J. P., Landsberg, W., Dewaele, P., McQuade, R. D., Loze, J. Y., Hennicken, D., Kerselaers, W. (2010). Effects of adjunc-tive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial. Int J Neuro-psychopharmacol. 13(8): 1115–1125. Doi: 10.1017/S1461145710000490.Goldberg, J. (2017). 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There are 3 citations in total.

Details

Primary Language English
Subjects Sports Medicine
Journal Section Articles
Authors

Hatice Toy

ERKUT Tutkun

ITIR Tarı Cömert

Publication Date April 30, 2019
Acceptance Date April 1, 2019
Published in Issue Year 2019 Volume: 21 Issue: 1

Cite

APA Toy, H., Tutkun, E., & Tarı Cömert, I. (2019). The role of exercıse ın reducıng the sıde effects of antıpsıcotıcs used ın the treatment of bıpolar dısorders. Turkish Journal of Sport and Exercise, 21(1), 96-109. https://doi.org/10.15314/tsed.542914
AMA Toy H, Tutkun E, Tarı Cömert I. The role of exercıse ın reducıng the sıde effects of antıpsıcotıcs used ın the treatment of bıpolar dısorders. Turk J Sport Exe. April 2019;21(1):96-109. doi:10.15314/tsed.542914
Chicago Toy, Hatice, ERKUT Tutkun, and ITIR Tarı Cömert. “The Role of exercıse ın reducıng the sıde Effects of antıpsıcotıcs Used ın the Treatment of bıpolar dısorders”. Turkish Journal of Sport and Exercise 21, no. 1 (April 2019): 96-109. https://doi.org/10.15314/tsed.542914.
EndNote Toy H, Tutkun E, Tarı Cömert I (April 1, 2019) The role of exercıse ın reducıng the sıde effects of antıpsıcotıcs used ın the treatment of bıpolar dısorders. Turkish Journal of Sport and Exercise 21 1 96–109.
IEEE H. Toy, E. Tutkun, and I. Tarı Cömert, “The role of exercıse ın reducıng the sıde effects of antıpsıcotıcs used ın the treatment of bıpolar dısorders”, Turk J Sport Exe, vol. 21, no. 1, pp. 96–109, 2019, doi: 10.15314/tsed.542914.
ISNAD Toy, Hatice et al. “The Role of exercıse ın reducıng the sıde Effects of antıpsıcotıcs Used ın the Treatment of bıpolar dısorders”. Turkish Journal of Sport and Exercise 21/1 (April 2019), 96-109. https://doi.org/10.15314/tsed.542914.
JAMA Toy H, Tutkun E, Tarı Cömert I. The role of exercıse ın reducıng the sıde effects of antıpsıcotıcs used ın the treatment of bıpolar dısorders. Turk J Sport Exe. 2019;21:96–109.
MLA Toy, Hatice et al. “The Role of exercıse ın reducıng the sıde Effects of antıpsıcotıcs Used ın the Treatment of bıpolar dısorders”. Turkish Journal of Sport and Exercise, vol. 21, no. 1, 2019, pp. 96-109, doi:10.15314/tsed.542914.
Vancouver Toy H, Tutkun E, Tarı Cömert I. The role of exercıse ın reducıng the sıde effects of antıpsıcotıcs used ın the treatment of bıpolar dısorders. Turk J Sport Exe. 2019;21(1):96-109.

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