Abstract
Endocrine
disruptors are mixtures of exogenous substances or substances that alter the
development and function of the endocrine system. These substances effect on
hormone production, release, attachment, transport, activity, destruction and
body excretion.
Compounds with endocrine disrupting effect can be examined in three groups.
1. Synthetic endocrine disruptors are found in some products used in the
industry, agriculture and at home. Diethylstilbestrol(DES) is the most known.
2. Natural endocrine disruptors do not usually cause significant side effects
because they are excreted in the body without accumulating in the tissues.
3. Environmental endocrine disruptors are chemicals and various environmental
pollutants developed for use in the industrial field. Enviromental pollutants
developed of the mineralization of biocides, intecticides, herbicides,
fungicides, industrial chemicals (bisphenol A, polyvinyl carbon ) and other
chemicals get involved in this group.
The studies show that endocrine disruptors have different effect mechanisms and
pathogenesis on many periods of women’s life, from puberty to menopause.
(Diamanti-Kandarakis et al.,2010)
Endocrine disruptors in women can lead to early/late puberty, polycystic ovary
syndrome, decreased fertility, infertility, endometriosis, early ovary
insufficiency, uterine tumors, aneuploidia, pregnancy complications, breast
tumors and endometrial tumors. (Diamanti-Kandarakis et al.,2009)
The studies show that endocrine disruptors can be lead to infertility, decline
in sperm quality, urogenital tumors (hypospadias, cryptorchidism) and
testicular germ cell tumors.(Sharpe and Skakkabaek et al.,2003)
Many studies have shown that endocrine disruptors have health-damaging effects.
Many endocrine disruptors have the ability to accumulate in our body as they
can be stored in the fat tissue. Today, it is impossible to be completely
protect against endocrine disrupting agents. For this reason, lifestyle changes
become important in order to minimize the effects of endocrine disruptors on
our health.
Adequate and balanced nutritional habits should be developed to protect against
the effects of endocrine disruptors.
Keywords:
Endocrine,
Disruptors, Reproductive System
References
- Onur Acar, Muhsin Akbaba, Burak Kurt Çukurova University Faculty of Medicine Department of Public Health
Abstract
References
- Onur Acar, Muhsin Akbaba, Burak Kurt Çukurova University Faculty of Medicine Department of Public Health
Details
| Journal Section | Articles |
|---|---|
| Authors | |
| Publication Date | November 1, 2017 |
| Published in Issue | Year 2017 Volume 2, Issue 1(4) |