MISSED DIAGNOSES AND THE SILENT ENEMY THREATENING OUR HEALTH: SOFT TISSUE RHEUMATIC DISEASES

Year 2025, Volume: 3 Issue: 1, 51 - 67, 27.10.2025

Muhammed Celal Eryilmaz

https://doi.org/10.5281/zenodo.17347000

Abstract

Soft tissue rheumatic diseases (STRD) encompass a wide variety of conditions characterized by inflammation and degeneration of connective tissues surrounding joints, including muscles, tendons, and ligaments. This review examines the epidemiology, pathophysiology, clinical presentation, diagnostic criteria, and management strategies associated with STRD. Epidemiological studies indicate that these diseases have a significant prevalence in various populations due to the influence of genetic, environmental, and lifestyle factors. Pathophysiological mechanisms involve immune dysregulation and chronic inflammation, which can lead to symptoms such as pain, swelling, and functional impairment. Accurate diagnosis is quite challenging due to overlapping symptoms with other rheumatic diseases. Clinical evaluations require a comprehensive approach integrating imaging and laboratory tests. Management strategies for STRD are multifaceted, combining pharmacological interventions such as NSAIDs and DMARDs with non-pharmacological approaches like physical therapy and lifestyle modifications. Despite advances in treatment, significant research gaps remain, particularly regarding the prevalence and pathophysiology of emerging soft tissue disorders. This review emphasizes the importance of a collaborative, team-based approach to improve patient care and outcomes for individuals affected by STRD.

Keywords

Fibromyalgia , Polymyalgia Rheumatica , Degenerative Diseases , Connective Tissues , Inflammation

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