Comparison of Antimicrobial Activity in the Skin Secretion of Same Anurans from Turkey

Year 2017, Volume: 1 Issue: 2, 85 - 94, 01.12.2017

Uğur Cengiz Erişmiş Safiye Elif Korcan

Abstract

Membrane-active cationic antimicrobial peptides (CAMPs) are a new class of antibiotics produced by
amphibian skin. In this study, Frog (Bombina bombina, Rana dalmatina, Rana macrocnemis, Bufo bufo, Bufo
viridis, Bufo verrocosmisscus, Pelodytes caucasicus, Pelophylax ridibunda, Pelophylax caralitana) skin
secretion was obtained from the dorsal skin using gentle transdermal electrical stimulation. Antimicrobial
effects of prepared extracts on the tested microorganisms were determined by using different solvents. In
vitro antimicrobial activity studies were carried out by Agar-Disc Diffusion Method. Antibacterial and
antiyeast potential of different extracts were obtained from the skin secretions were assessed in terms of
zone of inhibition of bacterial growth. According to our findings, all the extracts of skin secretion were
obtained from different anurans, exhibit antimicrobial activity

Keywords

CAMP , Frog , antimicrobial