Research Article

IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN

Volume: 30 Number: 2 August 20, 2025
TR EN

IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN

Abstract

Vertebral compression fractures are common conditions, particularly in the aging population, often linked to osteoporosis and other degenerative diseases. Non-traumatic vertebral compression fractures (VCFs) can be difficult to identify from medical images, especially those that do not show signs of trauma. This has led to a demand for more effective and automated detection methods. This study proposes a hybrid deep learning approach that uses DenseNet and Generative Adversarial Networks (GANs) to detect nontraumatic VCFs from computed tomography (CT) images. A dataset consisting of patient CT scans was used, including 101 images with confirmed fractures and 99 images without fractures. Our hybrid model demonstrated superior accuracy to conventional methods, showing promising results in distinguishing between fractured and non-fractured vertebrae. This automated method could aid radiologists in early diagnosis and treatment planning by decreasing the time needed for manual image analysis and improving diagnostic accuracy. The combination of DenseNet and GANs demonstrates the effectiveness of using advanced deep-learning techniques for medical image classification, opening the door for future applications in automated medical diagnosis.

Keywords

Ethical Statement

This research was conducted in accordance with the ethical guidelines outlined in the Declaration of Helsinki and was approved by the Ethics Committee of Istanbul University-Cerrahpasa (Approval No: 409356, Date: 20.06.2022).

References

  1. Alsaidi, M., Jan, M. T., Altaher, A., Zhuang, H., & Zhu, X. (2024). Tackling the class imbalanced dermoscopic image classification using data augmentation and GAN. Multimedia Tools and Applications, 83(16), 49121-49147. doi.org/10.1007/s11042-023-17067-1
  2. Atasever, S., Azginoglu, N., Terzi, D. S., & Terzi, R. (2023). A comprehensive survey of deep learning research on medical image analysis with focus on transfer learning. Clinical imaging, 94, 18-41. doi.org/10.1016/j.clinimag.2022.11.003
  3. Bahrami, A., Karimian, A., & Arabi, H. (2021). Comparison of different deep learning architectures for synthetic CT generation from MR images. Physica Medica, 90, 99-107. doi.org/10.1016/j.ejmp.2021.09.006
  4. Bastidas-Rodriguez, M. X., Polania, L., Gruson, A., & Prieto-Ortiz, F. (2020). Deep Learning for fractographic classification in metallic materials. Engineering Failure Analysis, 113, 104532. oi.org/10.1016/j.engfailanal.2020.104532
  5. Ding, Z., Li, H., Guo, Y., Zhou, D., Liu, Y., & Xie, S. (2023). M4fnet: Multimodal medical image fusion network via multi-receptive-field and multi-scale feature integration. Computers in Biology and Medicine, 159, 106923. doi.org/10.1016/j.compbiomed.2023.106923
  6. Faiella, E., Pacella, G., Altomare, C., Bernetti, C., Sarli, M., Cea, L., ... & Grasso, R. F. (2022). Percutaneous vertebroplasty: A minimally invasive procedure for the management of vertebral compression fractures. Osteology, 2(4), 139-151. doi.org/10.3390/osteology2040017
  7. Ferdousi, R., Yang, C., Hossain, M. A., Laamarti, F., Hossain, M. S., & Saddik, A. E. (2024). Generative Model-Driven Synthetic Training Image Generation: An Approach to Cognition in Railway Defect Detection. Cognitive Computation, 1-16. doi.org/10.1007/s12559-024-10283-3
  8. Fei, R., Yao, Q., Zhu, Y., Xu, Q., Li, A., Wu, H., & Hu, B. (2020). Deep Learning Structure for Cross‐Domain Sentiment Classification Based on Improved Cross Entropy and Weight. Scientific Programming, 2020(1), 3810261. doi.org/10.1155/2020/3810261

Details

Primary Language

English

Subjects

Software Engineering (Other)

Journal Section

Research Article

Early Pub Date

July 30, 2025

Publication Date

August 20, 2025

Submission Date

September 27, 2024

Acceptance Date

March 11, 2025

Published in Issue

Year 2025 Volume: 30 Number: 2

APA
Türkmen, M., & Orman, Z. (2025). IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN. Uludağ Üniversitesi Mühendislik Fakültesi Dergisi, 30(2), 339-354. https://doi.org/10.17482/uumfd.1557032
AMA
1.Türkmen M, Orman Z. IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN. UUJFE. 2025;30(2):339-354. doi:10.17482/uumfd.1557032
Chicago
Türkmen, Murat, and Zeynep Orman. 2025. “IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN”. Uludağ Üniversitesi Mühendislik Fakültesi Dergisi 30 (2): 339-54. https://doi.org/10.17482/uumfd.1557032.
EndNote
Türkmen M, Orman Z (August 1, 2025) IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN. Uludağ Üniversitesi Mühendislik Fakültesi Dergisi 30 2 339–354.
IEEE
[1]M. Türkmen and Z. Orman, “IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN”, UUJFE, vol. 30, no. 2, pp. 339–354, Aug. 2025, doi: 10.17482/uumfd.1557032.
ISNAD
Türkmen, Murat - Orman, Zeynep. “IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN”. Uludağ Üniversitesi Mühendislik Fakültesi Dergisi 30/2 (August 1, 2025): 339-354. https://doi.org/10.17482/uumfd.1557032.
JAMA
1.Türkmen M, Orman Z. IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN. UUJFE. 2025;30:339–354.
MLA
Türkmen, Murat, and Zeynep Orman. “IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN”. Uludağ Üniversitesi Mühendislik Fakültesi Dergisi, vol. 30, no. 2, Aug. 2025, pp. 339-54, doi:10.17482/uumfd.1557032.
Vancouver
1.Murat Türkmen, Zeynep Orman. IDENTIFICATION OF NON-TRAUMATIC VERTEBRAL COMPRESSION FRACTURES IN CT IMAGES USING A HYBRID DEEP LEARNING MODEL COMBINING DENSENET AND GAN. UUJFE. 2025 Aug. 1;30(2):339-54. doi:10.17482/uumfd.1557032

Announcements:

30.03.2021-Beginning with our April 2021 (26/1) issue, in accordance with the new criteria of TR-Dizin, the Declaration of Conflict of Interest and the Declaration of Author Contribution forms fulfilled and signed by all authors are required as well as the Copyright form during the initial submission of the manuscript. Furthermore two new sections, i.e. ‘Conflict of Interest’ and ‘Author Contribution’, should be added to the manuscript. Links of those forms that should be submitted with the initial manuscript can be found in our 'Author Guidelines' and 'Submission Procedure' pages. The manuscript template is also updated. For articles reviewed and accepted for publication in our 2021 and ongoing issues and for articles currently under review process, those forms should also be fulfilled, signed and uploaded to the system by authors.