Research Article

Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients

Volume: 52 July 8, 2026
EN TR

Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients

Abstract

This study aims to evaluate benign and malignant axillary lymph nodes (LN) in breast cancer using multiparametric ultrasound (US). The morphological characteristics, stiffness, and VI differences between 52 benign and malignant LNs were statistically evaluated using B-mode US, shear wave elastography (SWE), and superb microvascular imaging (SMI) before biopsy. Significant cutoff values were determined using receiver operating characteristic (ROC) curve analysis. Malignant lymph nodes had higher short-axis diameters (SD), lower long-axis diameter/short axis diameter ratios (LD/SD), and increased cortical thickness (p=0.026, p=0.044, p=0.004, p=0.000, respectively). A cortical thickness above 3.1 mm (AUC: 0.751, sensitivity: 94.1%, specificity: 51.4%, p=0.0003), SD greater than 8.4 mm (AUC: 0.692, sensitivity: 41.1%, specificity: 91.4%, p= 0.0141), LD/SD ≤2 (AUC: 0.664, sensitivity: 76.5%, specificity: 48.6%, p=0.0355) and, a mean elasticity value above 26.2 kPa (AUC: 0.861, sensitivity: 70.6%, specificity: 91.4%, p<0.0001) were identified as the best cutoff values for detecting metastasis. Since multiparametric ultrasound provides valuable information for detecting metastatic lymph nodes, we recommend multiparametric assessment rather than B-mode ultrasound alone.

Keywords

References

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Details

Primary Language

English

Subjects

Radiology and Organ Imaging

Journal Section

Research Article

Publication Date

July 8, 2026

Submission Date

March 9, 2026

Acceptance Date

June 1, 2026

Published in Issue

Year 2026 Volume: 52

APA
Erdemli Gürsel, B., Özpar, R., Ercan, İ., & Gökalp, G. (2026). Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients. Journal of Uludağ University Medical Faculty, 52. https://doi.org/10.32708/uutfd.1906063
AMA
1.Erdemli Gürsel B, Özpar R, Ercan İ, Gökalp G. Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients. Journal of Uludağ University Medical Faculty. 2026;52. doi:10.32708/uutfd.1906063
Chicago
Erdemli Gürsel, Başak, Rifat Özpar, İlker Ercan, and Gökhan Gökalp. 2026. “Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients”. Journal of Uludağ University Medical Faculty 52 (July). https://doi.org/10.32708/uutfd.1906063.
EndNote
Erdemli Gürsel B, Özpar R, Ercan İ, Gökalp G (July 1, 2026) Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients. Journal of Uludağ University Medical Faculty 52
IEEE
[1]B. Erdemli Gürsel, R. Özpar, İ. Ercan, and G. Gökalp, “Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients”, Journal of Uludağ University Medical Faculty, vol. 52, July 2026, doi: 10.32708/uutfd.1906063.
ISNAD
Erdemli Gürsel, Başak - Özpar, Rifat - Ercan, İlker - Gökalp, Gökhan. “Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients”. Journal of Uludağ University Medical Faculty 52 (July 1, 2026). https://doi.org/10.32708/uutfd.1906063.
JAMA
1.Erdemli Gürsel B, Özpar R, Ercan İ, Gökalp G. Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients. Journal of Uludağ University Medical Faculty. 2026;52. doi:10.32708/uutfd.1906063.
MLA
Erdemli Gürsel, Başak, et al. “Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients”. Journal of Uludağ University Medical Faculty, vol. 52, July 2026, doi:10.32708/uutfd.1906063.
Vancouver
1.Başak Erdemli Gürsel, Rifat Özpar, İlker Ercan, Gökhan Gökalp. Multiparametric Ultrasound Evaluation of Axillary Lymph Nodes in Breast Cancer Patients. Journal of Uludağ University Medical Faculty. 2026 Jul. 1;52. doi:10.32708/uutfd.1906063

ISSN: 1300-414X, e-ISSN: 2645-9027

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