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Adjuvant Chemotherapy in Locally Advanced Bladder Cancer: Retrospective Analysis of 32 Cases

Year 2011, Volume: 37 Issue: 3, 123 - 125, 01.09.2011

Abstract

In this study, patients who received adjuvant chemotherapy for locally advanced bladder cancer were retrospectively analyzed. A total of 32 patients received gemcitabine (%18.8), cisplatin plus gemcitabine (%50), carboplatin plus gemcitabine (%15,6) or MVAC (Methotrexate, vinblastine, doxorubicin, and cisplatin). The most common adverse effect was myelosuppression during chemotherapy administration. Treatment-related died was not observed. The median overall and disease-free survival was 23 months (range, 18.7-27.4) and 17.8 months (range, 12.7-22.9), respectively. We concluded that our results were comparable to those in the literature.

Lokal İleri Mesane Kanserinde Adjuvan Kemoterapi: 32 Ol-gunun Retrospektif Analizi

Year 2011, Volume: 37 Issue: 3, 123 - 125, 01.09.2011

Abstract

Bu çalışmada, lokal ileri mesane kanseri nedeniyle adjuvant kemoterapi alan hastalar retrospektif olarak analiz edildi. Toplam 32 hasta gemsitabin (%18.8), sisplatin+gemsitabin (%50), carboplatin+gemsitabin (%15.6) veya MVAC (Metotreksat, vinblastin, doksorubisin ve sisplatin) (%15.6) tedavisi aldı. Tedaviler sırasında en sık görülen yan etki kemik iliği toksisitesi idi. Tedaviye bağlı ölüm gözlenmedi. Medyan genel ve hastalıksız sağkalım süreleri sırasıyla 23 ay (18.7-27.4) ve 17.8 ay (12.7-22.9) idi. Verilerimizin literatür ile uyumlu olduğu sonucuna varıldı.

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Details

Other ID JA34BH84VP
Authors

Erdem Çubukçu This is me

Mustafa Canhoroz This is me

Ömer Fatih Ölmez This is me

Nilüfer Avcı This is me

Sinem Çubukçu This is me

Ünsal Akçalı This is me

Mustafa Sakallı This is me

Muharrem Bayrak This is me

Özkan Kanat This is me

Ender Kurt This is me

Türkkan Evrensel This is me

Osman Manavoğlu This is me

Publication Date September 1, 2011
Published in Issue Year 2011 Volume: 37 Issue: 3

Cite

AMA Çubukçu E, Canhoroz M, Ölmez ÖF, et al. Adjuvant Chemotherapy in Locally Advanced Bladder Cancer: Retrospective Analysis of 32 Cases. Journal of Uludağ University Medical Faculty. September 2011;37(3):123-125.

ISSN: 1300-414X, e-ISSN: 2645-9027

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